Results 81 to 90 of about 11,198,861 (420)
Differential elasticity in lineage segregation of embryonic stem cells [PDF]
arXiv, 2022 The question of what guides lineage segregation is central to development, where cellular differentiation leads to segregated cell populations destined for specialized functions. Here, using optical tweezers measurements of mouse embryonic stem cells (mESCs), we reveal a mechanical mechanism based on differential elasticity in the second lineage ...
arxiv
Violation of cell lineage restriction compartments in the chick hindbrain [PDF]
, 1994 Previous cell lineage studies indicate that the repeated neuromeres of the chick hindbrain, the rhombomeres, are cell lineage restriction compartments. We have extended these results and tested if the restrictions are absolute. Two different cell marking
Birgbauer, Eric, Fraser, Scott E.
core
Human natural killer cell committed thymocytes and their relation to the T cell lineage. [PDF]
, 1993 Recent studies have demonstrated that mature natural killer (NK) cells can be grown from human triple negative (TN; CD3-, CD4-, CD8-) thymocytes, suggesting that a common NK/T cell precursor exists within the thymus that can give rise to both NK cells ...
Lanier, LL +3 more
core +1 more source
Cell RegenerationThe COVID-19 pandemic has caused a global health crisis and significant social economic burden. While most individuals experience mild or non-specific symptoms, elderly individuals are at a higher risk of developing severe symptoms and life-threatening ...
Yuan Yu +7 more
doaj +1 more source
eLife, 2020 Clones of excitatory neurons derived from a common progenitor have been proposed to serve as elementary information processing modules in the neocortex.
Cathryn R Cadwell +16 more
doaj +1 more source
Cell types as species: Exploring a metaphor
Frontiers in Plant Science, 2022 The concept of “cell type,” though fundamental to cell biology, is controversial. Cells have historically been classified into types based on morphology, physiology, or location.
Jeff J. Doyle
doaj +1 more source
Insights into the Development of the Adult Leydig Cell Lineage from Stem Leydig Cells
Frontiers in Physiology, 2017 Adult Leydig cells (ALCs) are the steroidogenic cells in the testes that produce testosterone. ALCs develop postnatally from a pool of stem cells, referred to as stem Leydig cells (SLCs). SLCs are spindle-shaped cells that lack steroidogenic cell markers,
Leping Ye +4 more
semanticscholar +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain [PDF]
, 2020 Chromatin remodelling and transcription factors play important roles in lineage commitment and development through control of gene expression. Activation of selected lineage-specific genes and repression of alternative lineage-affiliated genes results in
Biasutto, Antonio J +4 more
core +1 more source
Maps of variability in cell lineage trees
PLOS Computational Biology, 2018 AbstractNew approaches to lineage tracking allow the study of cell differentiation over many generations of cells during development in multicellular organisms. Understanding the variability observed in these lineage trees requires new statistical methods.
Sarah M. Russell +6 more
openaire +7 more sources