Results 61 to 70 of about 1,314 (159)
Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents
Biochemistry Research International, Volume 2026, Issue 1, 2026.Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Livia Ramos Santiago +6 more
wiley +1 more source
Cone snail genome sheds light on venom evolution
, 2021 <strong> This week in <em> GigaScience </em> we published the genome of the mediterranean cone snail, <em> Lautoconus ventricosus </em> . Cone snails produce a wide variety of powerful toxins and the new chromosome-scale genome assembly opens the door for detailed investigations of their diversity and evolution.
openaire +1 more source
Marine Drugs, 2017 Conotoxins in the venom of cone snails (Conus spp.) are a mixture of active peptides that work as blockers, agonists, antagonists, or inactivators of various ion channels.
Yu Huang +4 more
doaj +1 more source
Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails [PDF]
Nature Communications, 2014 Venomous animals are thought to inject the same combination of toxins for both predation and defence, presumably exploiting conserved target pharmacology across prey and predators. Remarkably, cone snails can rapidly switch between distinct venoms in response to predatory or defensive stimuli.
Dutertre, Sébastien +11 more
openaire +3 more sources
Identification of “alpha-conotoxin-like” Peptide in Conus pennaceus Born, 1778, Venom [PDF]
بومشناسی آبزیان, 2018 Conic snails are slow-moving carnivorous that use a very powerful venom to hunt. This venom is a combination of different toxins from the family of conototoxins.
Hadi Dehghani +4 more
doaj
Scientific Reports, 2018 Cone snail venoms have separately evolved for predation and defense. Despite remarkable inter- and intra-species variability, defined sets of synergistic venom peptides (cabals) are considered essential for prey capture by cone snails.
S. W. A. Himaya +2 more
doaj +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2020 Objective: To determine the new M-superfamily conotoxins from molluscivorous snail Conus bandanus in Vietnam. Methods: Conus bandanus venom was fractionated and purified on HPLC system with an analytical reversed-phase C18 column in order to screen small
Nguyen Bao +2 more
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Toxins, 2022 Animal venoms are a rich source of pharmacological compounds with ecological and evolutionary significance, as well as with therapeutic and biotechnological potentials.
Fabrice Saintmont +3 more
doaj +1 more source
Journal of Biogeography, Volume 52, Issue 10, October 2025.ABSTRACT Aim Genetic diversity and connectivity are crucial to informing the conservation strategy for deep‐sea organisms, especially those threatened by deep‐sea mining. The vent mussel Bathymodiolus septemdierum has an extraordinary trans‐oceanic distribution range across the Indo‐West Pacific including numerous sites eyed for exploitation.
Qin Mao +10 more
wiley +1 more source
Conotoxins: Therapeutic Potential and Application
Marine Drugs, 2006 The pharmacological variety of conotoxins, diverse peptides found in the venoms of marine cone snails, is well recognized. Venoms from each of the estimated 500 species of cone snails contain 50 to 200 distinct biologically active peptides.
Richard T. Layer, J. Michael McIntosh
doaj +1 more source