Results 21 to 30 of about 59,000 (187)

Various forms of tissue damage and danger signals following hematopoietic stem-cell transplantation [PDF]

, 2015
Hematopoietic stem-cell transplantation (HSCT) is the most potent curative therapy for many malignant and non-malignant disorders. Unfortunately, a major complication of HSCT is graft-versus-host disease (GVHD), which is mediated by tissue damage ...
Paczesny, Sophie, Ramadan, Abdularouf
core   +5 more sources

Extracellular ATP acts as a damage-associated molecular pattern (DAMP) signal in plants [PDF]

Frontiers in Plant Science, 2014
As sessile organisms, plants have evolved effective mechanisms to protect themselves from environmental stresses. Damaged (i.e., wounded) plants recognize a variety of endogenous molecules as danger signals, referred to as damage-associated molecular patterns (DAMPs).
Tanaka, Kiwamu, Choi, Jeongmin, Cao, Yangrong, Stacey, Gary   +3 more
openaire   +4 more sources

Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle [PDF]

, 2014
Inflammation is the ultimate response to the constant challenges of the immune system by microbes, irritants or injury. The inflammatory cascade initiates with the recognition of microorganism-derived pathogen associated molecular patterns (PAMPs) and ...
Abe, Alexeyev, Andersson, Andersson, Ba, Babior, Bartoloni, Berger, Blyth, Brill, Brinkmann, Cadet, Collins, Cooke, Csanád Z. Bachrati, David, Ding, Dostert, Ermakov, Ermakov, Ferguson, Fuchs, Gahan, Gedik, Gehrke, Hajizadeh, Halle, Hiramoto, Huang, Huang, Huang, Huttunen, Ishikawa, Ivana, Ivanov, Jahr, Jia, Kang, Kanneganti, Kazak, Klebanoff, Knaapen, Kondo, Kostyuk, Kostyuk, Krieg, Kuechle, Lane, Lange, Latz, Li, Malins, Mariathasan, Munoz-Gamez, Nakahira, Oka, Pacher, Parvatiyar, Pasheva, Pinti, Polk, Rathinam, Saitoh, Saxena, Scaffidi, Schroder, Shimada, Shokolenko, Sun, Suter, Suzuki, Swindall, Tadie, Taguchi, Takeda, Takeda, Tang, Tang, Thomson, Timea Pálmai-Pallag, Unterholzner, Urbonaviciute, Venereau, Volcic, Weinberg, Weiss, Wilson, Wu, Yan, Yang, Yoshida, Yoshihara, Yotsumoto, You, Yousefi, Zhang, Zhang, Zhang, Zhang, Zhang, Zhou   +100 more
core   +1 more source

Transplantation and Damage-Associated Molecular Patterns (DAMPs)

American Journal of Transplantation, 2016
Upon solid organ transplantation and during cancer immunotherapy, cellular stress responses result in the release of damage-associated molecular patterns (DAMPs). The various cellular stresses have been characterized in detail over the last decades, but a unifying classification based on clinically important aspects is lacking.
Land, W.G., Agostinis, Patrizia, Gasser, S., Garg, Abhishek, Linkermann, A.   +4 more
openaire   +3 more sources

DAMPs from death to new life

Frontiers in Immunology, 2015
Our body handles tissue damage by activating the immune system in response to intracellularmolecules released by injured tissues (Damage-Associated Molecular Patterns, DAMPs), in a similar way as it detects molecular motifs conserved in pathogens ...
Emilie eVénéreau, Emilie eVénéreau, Chiara eCeriotti, Marco Emilio Bianchi, Marco Emilio Bianchi   +4 more
doaj   +1 more source

Exosomes in Sepsis

Frontiers in Immunology, 2020
Sepsis is a severe state of infection with high mortality. Pathogen-associated molecular patterns and damage-associated molecular patterns (DAMPs) initiate dysregulated systemic inflammation upon binding to pattern recognition receptors.
Atsushi Murao, Max Brenner, Max Brenner, Monowar Aziz, Ping Wang, Ping Wang, Ping Wang   +6 more
doaj   +1 more source

A damage-associated molecular patterns-related gene signature for the prediction of prognosis and immune microenvironment in children stage III acute lymphoblastic leukemia

Frontiers in Pediatrics, 2022
BackgroundImmunogenic cell death (ICD)-mediated immune response provides a strong rationale to overcome immune evasion in acute lymphoblastic leukemia (ALL). ICD will produce damage-associated molecular patterns (DAMPs) in tumor microenvironment. However,
Feng Zhao, Feng Zhao, Qiuyu Lin, Xiayu Xiang, Wei Xiang, Wei Xiang   +5 more
doaj   +1 more source

Many faces of DAMPs in cancer therapy [PDF]

, 2013
A new concept of immunogenic cell death (ICD) has recently been proposed. The immunogenic characteristics of this cell death mode are mediated mainly by molecules called ‘damage-associated molecular patterns’ (DAMPs), most of which are recognized by ...
Aaes, Tania Love, Bachert, Claus, Krysko, Dmitri, Krysko, Olga, Vandenabeele, Peter   +4 more
core   +1 more source

Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]

, 2020
Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P., Leuvenink, Henri G. D., Nieuwenhuijs-Moeke, Gertrude J., Pischke, Soren E., Ploeg, Rutger J., Pol, Robert A., Sanders, Jan Stephan F., Struys, Michel   +7 more
core   +2 more sources

The immune suppressive properties of damage associated molecular patterns in the setting of sterile traumatic injury

Frontiers in Immunology, 2023
Associated with the development of hospital-acquired infections, major traumatic injury results in an immediate and persistent state of systemic immunosuppression, yet the underlying mechanisms are poorly understood.
Emily Horner, Janet M. Lord, Janet M. Lord, Jon Hazeldine, Jon Hazeldine   +4 more
doaj   +1 more source