Results 1 to 10 of about 9,951 (96)

The Effect of Epigenetic Age Acceleration on Atopic Dermatitis: A Mendelian Randomization Study [PDF]

Clinical, Cosmetic and Investigational Dermatology
Yu Xin, Bingqing Dai, Jun Wang Department of Dermatology, Yijishan Hospital Affiliated with Wannan Medical College, Wuhu, Anhui, People’s Republic of ChinaCorrespondence: Jun Wang, Email 1813wj@163.comIntroduction: Atopic dermatitis (AD) is a chronic ...
Xin Y, Dai B, Wang J
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Epigenetic age acceleration and allergic diseases: a bidirectional two-sample Mendelian randomization study [PDF]

Clinical Epigenetics
Objective The epigenetic clock has been regarded as a highly accurate predictor of capturing the complexity between aging and the epigenome. However, there is limited understanding of the epigenetic clock in allergic diseases.
Junfang Sun, Guozhen Fan, Lixin Hu, Zheng Hai Qu, Hong Jiang   +4 more
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Unraveling the causal association of epigenetic age acceleration with common oral diseases and its underlying mechanisms: findings from Mendelian randomization and integrative genetic analysis [PDF]

Clinical Epigenetics
Objective The epigenetic clock is recognized as a highly accurate predictor of biological aging, but the relationship between epigenetic age acceleration and oral diseases remains poorly understood. This study aimed to investigate the causal associations
Lianjie Peng, Shengzhe Nie, Yihua Sun, Shihan Wang, Yaying Wang, Zhichao Liu   +5 more
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Epigenetic age acceleration and rheumatoid arthritis: an NHANES-based analysis and survival prediction models [PDF]

Clinical Epigenetics
Objective Epigenetic aging has been confirmed to be associated with the pathogenesis of rheumatoid arthritis (RA), however, its role in the prognosis of RA remains unclear.
Yuhang Ou, Zhihao Wang, Yunbo Yuan, Yuze He, Wenhao Li, Hao Ren, Junhong Li, Siliang Chen, Yanhui Liu   +8 more
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Evaluation of Epigenetic Age Acceleration Scores and Their Associations with CVD-Related Phenotypes in a Population Cohort

Biology, 2022
We evaluated associations between nine epigenetic age acceleration (EAA) scores and 18 cardiometabolic phenotypes using an Eastern European ageing population cohort richly annotated for a diverse set of phenotypes (subsample, n = 306; aged 45–69 years ...
Olga Chervova, Elizabeth Chernysheva , Kseniia Panteleeva , Tyas Arum Widayati , Natalie Hrbkova, Jadesada Schneider , Vladimir Maximov , Andrew Ryabikov , Taavi Tillmann , Hynek Pikhart, Martin Bobak , Vitaly Voloshin , Sofia Malyutina , Stephan Beck    +13 more
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Metal mixtures and DNA methylation measures of biological aging in American Indian populations

Environment International, 2023
Introduction: Native American communities suffer disproportionately from elevated metal exposures and increased risk for cardiovascular diseases and diabetes. DNA methylation is a sensitive biomarker of aging-related processes and novel epigenetic-based “
Kaila Boyer, Arce Domingo-Relloso, Enoch Jiang, Karin Haack, Walter Goessler, Ying Zhang, Jason G. Umans, Daniel W. Belsky, Shelley A. Cole, Ana Navas-Acien, Allison Kupsco   +10 more
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Epigenetic Age Acceleration and Hearing: Observations From the Baltimore Longitudinal Study of Aging

Frontiers in Aging Neuroscience, 2021
Objectives: Age-related hearing loss (ARHL) is highly prevalent among older adults, but the potential mechanisms and predictive markers for ARHL are lacking.
Pei-Lun Kuo, Ann Zenobia Moore, Frank R. Lin, Frank R. Lin, Luigi Ferrucci   +4 more
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DNA methylation age at birth and childhood: performance of epigenetic clocks and characteristics associated with epigenetic age acceleration in the Project Viva cohort

Clinical Epigenetics, 2023
Background Epigenetic age acceleration (EAA) and epigenetic gestational age acceleration (EGAA) are biomarkers of physiological development and may be affected by the perinatal environment.
Anne K. Bozack, Sheryl L. Rifas-Shiman, Diane R. Gold, Zachary M. Laubach, Wei Perng, Marie-France Hivert, Andres Cardenas   +6 more
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Associations between medium- and long-term exposure to air temperature and epigenetic age acceleration

Environment International, 2023
Climate change poses a serious threat to human health worldwide, while aging populations increase. However, no study has ever investigated the effects of air temperature on epigenetic age acceleration.
Wenli Ni, Nikolaos Nikolaou, Cavin K. Ward-Caviness, Susanne Breitner, Kathrin Wolf, Siqi Zhang, Rory Wilson, Melanie Waldenberger, Annette Peters, Alexandra Schneider   +9 more
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Time to relapse in chronic lymphocytic leukemia and DNA-methylation-based biological age

Clinical Epigenetics, 2023
Chronic lymphocytic leukemia (CLL) is a mature B cell neoplasm with a predilection for older individuals. While previous studies have identified epigenetic signatures associated with CLL, whether age-related DNA methylation changes modulate CLL relapse ...
Drew R. Nannini, Rene Cortese, Peter Egwom, Senthilnathan Palaniyandi, Gerhard C. Hildebrandt   +4 more
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