Results 81 to 90 of about 10,021 (160)

Probabilistic inference of epigenetic age acceleration from cellular dynamics

Nature Aging
Abstract The emergence of epigenetic predictors was a pivotal moment in geroscience, propelling the measurement and concept of biological aging into a quantitative era; however, while current epigenetic clocks show strong predictive power, they are data-driven in nature and are not based on the underlying biological mechanisms driving
Jan K. Dabrowski, Emma J. Yang, Samuel J. C. Crofts, Robert F. Hillary, Daniel J. Simpson, Daniel L. McCartney, Riccardo E. Marioni, Kristina Kirschner, Eric Latorre-Crespo, Tamir Chandra   +9 more
openaire   +2 more sources

Inclusion of epigenetic age acceleration in oncological trials

The Lancet Healthy Longevity, 2023
Bharat B, Mittal, Douglas E, Vaughan
openaire   +2 more sources

Epigenetic aging in anxiety disorders: diagnostic subtype differences and associations with social functioning

BMC Medicine
Background Anxiety disorders, including subtypes such as social anxiety disorder (SAD), panic disorder (PD), and generalized anxiety disorder (GAD), are among the most common psychiatric disorders.
Kazutaka Ohi, Daisuke Fujikane, Yasuhisa Oida, Kentaro Takai, Tatsuhide Ukisu, Maho Nakahara, Hiroki Murakami, Koji Fujita, Ayumi Kuramitsu, Yukimasa Muto, Shunsuke Sugiyama, Kiyoto Kasai, Shinsuke Koike, Kiyoyuki Kitaichi, Toshiki Shioiri   +14 more
doaj   +1 more source

Assessment of relationships between epigenetic age acceleration and multiple sclerosis: a bidirectional mendelian randomization study

Epigenetics & Chromatin
Background The DNA methylation-based epigenetic clocks are increasingly recognized for their precision in predicting aging and its health implications. Although prior research has identified connections between accelerated epigenetic aging and multiple ...
Hongwei Liu, Hanqing Zhang, Zhaoxu Yin, Miaomiao Hou   +3 more
doaj   +1 more source

Gradual DNA methylation changes reveal transcription factors implicated in metabolic dysfunction-associated steatotic liver disease progression and epigenetic age acceleration

Clinical Epigenetics
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide, but its pathophysiological mechanisms remain elusive.
Evelien Van Dijck, Steven Van Laere, Emilie Logie, Steven Timmermans, Erik Fransen, Joe Ibrahim, Timothy J. Kendall, Jonathan A. Fallowfield, Ligia M. Mateiu, Claude Libert, Guy Van Camp, An Verrijken, Luc Van Gaal, Sven Francque, Wim Van Hul, Wim Vanden Berghe   +15 more
doaj   +1 more source

Causal association of epigenetic age acceleration and risk of subacute thyroiditis: a bidirectional Mendelian randomization study

Clinical Epigenetics
Background Epigenetic age accelerations (EAAs) are a promising new avenue of research, yet their investigation in subacute thyroiditis (SAT) remains scarce.
Bingbing Shen, Yusheng Pu, Xiaofeng Zheng, Yang Liu, Lin Yang, Jiaye Liu, Zhihui Li   +6 more
doaj   +1 more source

Refining the Role of Epigenetic Age Acceleration in Cardiotoxicity Research. [PDF]

JACC CardioOncol
Cao J, Han W, Liu Y.
europepmc   +1 more source

PRC2-Related Epigenetic Age Acceleration in Acute Myeloid Leukemia with DNMT3A and IDH2 Mutations. [PDF]

Adv Biol (Weinh)
Yan Z, Yuan L, Wang J, Gu S, Lei Y.
europepmc   +1 more source

Comment on "The Effect of Epigenetic Age Acceleration on Atopic Dermatitis: A Mendelian Randomization Study" [Letter]. [PDF]

Clin Cosmet Investig Dermatol
Zhang Z.
europepmc   +1 more source

Dissecting epigenetic age acceleration in amyotrophic lateral sclerosis. [PDF]

Epigenomics
Merbaum P, Zwamborn R, Hop P, Sequencing Consortium PMA, van Rheenen W, Veldink J.   +5 more
europepmc   +1 more source