Results 1 to 10 of about 1,435 (170)
Elucidating the Functions of Non-Coding RNAs from the Perspective of RNA Modifications [PDF]
Non-Coding RNA, 2021 It is now commonly accepted that most of the mammalian genome is transcribed as RNA, yet less than 2% of such RNA encode for proteins. A majority of transcribed RNA exists as non-protein-coding RNAs (ncRNAs) with various functions. Because of the lack of
Venkata Naga Srikanth Garikipati +1 more
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Spliceosomal snRNA Epitranscriptomics [PDF]
Frontiers in Genetics, 2021 Small nuclear RNAs (snRNAs) are critical components of the spliceosome that catalyze the splicing of pre-mRNA. snRNAs are each complexed with many proteins to form RNA-protein complexes, termed as small nuclear ribonucleoproteins (snRNPs), in the cell ...
Pedro Morais, Hironori Adachi, Yi-Tao Yu
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The role of RNA-modifying proteins in renal cell carcinoma [PDF]
Cell Death and DiseaseGene expression is one of the most critical cellular processes. It is controlled by complex mechanisms at the genomic, epigenomic, transcriptomic, and proteomic levels. Any aberration in these mechanisms can lead to dysregulated gene expression.
Muna A. Alhammadi +3 more
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Editorial: Epitranscriptomics: The Novel RNA Frontier [PDF]
Frontiers in Bioengineering and Biotechnology, 2018 Giovanni Nigita +3 more
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The Impact of Epitranscriptomics on Antiviral Innate Immunity
Viruses, 2022 Epitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology.
Beril Mersinoglu +2 more
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Epitranscriptomics of SARS-CoV-2 Infection
Frontiers in Cell and Developmental Biology, 2022 Recent studies on the epitranscriptomic code of SARS-CoV-2 infection have discovered various RNA modifications, such as N6-methyladenosine (m6A), pseudouridine (Ψ), and 2′-O-methylation (Nm).
Amin Izadpanah +4 more
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Epitranscriptomics as a New Layer of Regulation of Gene Expression in Skeletal Muscle: Known Functions and Future Perspectives [PDF]
, 2023 Epitranscriptomics refers to post-transcriptional regulation of gene expression via RNA modifications and editing that affect RNA functions. Many kinds of modifications of mRNA have been described, among which are N6-methyladenosine (m6A), N1 ...
Belluti, Silvia +6 more
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Journal of Translational Medicine, 2023 Glioblastoma (GBM) comprises 45.6% of all primary malignant brain cancers and is one of the most common and aggressive intracranial tumors in adults.
Christian K. Ramsoomair +3 more
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Immunity and autoantibodies of a mouse strain with autistic-like behavior
Brain, Behavior, & Immunity - Health, 2020 Female and male mice of the BTBR T+Itpr3tf/J (BTBR) strain have behaviors that resemble autism spectrum disorder. In comparison to C57BL/6 (B6) mice, BTBR mice have elevated humoral immunity, in that they have naturally high serum IgG levels and generate
Mohammad Nizam Uddin +6 more
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RNA Modification Related Diseases and Sensing Methods
Applied Sciences, 2023 Epitranscriptomics is the study of RNA base modifications, including functionally relevant transcriptomic changes. Epitranscriptomics has been actively studied in recent years and has been reported to play important roles in development, homeostasis, the
Mayuka Ohkawa, Masamitsu Konno
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