Results 11 to 20 of about 2,313 (187)
RNA Modifications and Epitranscriptomics
Genomics, Proteomics & Bioinformatics, 2023 Chengqi Yi, Jianhua Yang
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Epitranscriptomics in myeloid malignancies
Blood Science, 2022 Li Han, Jianjun Chen, Rui Su
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Epitranscriptomic signatures in blood: emerging biomarkers for diagnosis of diabetes and its complications [PDF]
Frontiers in Cell and Developmental BiologyType 2 diabetes mellitus (T2DM) is a complex metabolic disorder characterized by chronic hyperglycemia, insulin resistance, and progressive β-cell dysfunction.
Marketa Hlavackova +8 more
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METTL4 regulates synaptic UCP2 N6-adenosine methylation to mediate pain hypersensitivity in female mice [PDF]
Cellular and Molecular Life SciencesEpitranscriptomics modifications play an important role in sex-dependent biological phenomena. N6-adenosine methylation (m6A), the most prevalent epitranscriptomics modification in eukaryotic mRNA, participates in regulating various sex-specific ...
Yanqiong Wu +15 more
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The epitranscriptome toolbox [PDF]
Cell, 2022 In the last decade, the notion that mRNA modifications are involved in regulation of gene expression was demonstrated in thousands of studies. To date, new technologies and methods allow accurate identification, transcriptome-wide mapping, and functional characterization of a growing number of RNA modifications, providing important insights into the ...
Moshitch-Moshkovitz, Sharon +2 more
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Environmental epitranscriptomics [PDF]
Environmental Research, 2020 Chemical modifications of RNA molecules have gained increasing attention since evidence emerged for their substantive roles in a range of biological processes, such as the stability and translation of mRNA transcripts. More than 150 modifications have been identified in different organisms to date, collectively known as the 'epitranscriptome', with 6 ...
Cayir, Akin +2 more
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Epitranscriptomics of SARS-CoV-2 Infection
Frontiers in Cell and Developmental Biology, 2022 Recent studies on the epitranscriptomic code of SARS-CoV-2 infection have discovered various RNA modifications, such as N6-methyladenosine (m6A), pseudouridine (Ψ), and 2′-O-methylation (Nm).
Amin Izadpanah +4 more
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Translating the epitranscriptome [PDF]
WIREs RNA, 2016 RNAmodifications are indispensable for the translation machinery to provide accurate and efficient protein synthesis. Whereas the importance of transfer RNA (tRNA) and ribosomal RNA (rRNA) modifications has been well described and is unquestioned for decades, the significance of internal messenger RNA (mRNA) modifications has only recently been ...
Hoernes, Thomas Philipp +1 more
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Journal of Translational Medicine, 2023 Glioblastoma (GBM) comprises 45.6% of all primary malignant brain cancers and is one of the most common and aggressive intracranial tumors in adults.
Christian K. Ramsoomair +3 more
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Immunity and autoantibodies of a mouse strain with autistic-like behavior
Brain, Behavior, & Immunity - Health, 2020 Female and male mice of the BTBR T+Itpr3tf/J (BTBR) strain have behaviors that resemble autism spectrum disorder. In comparison to C57BL/6 (B6) mice, BTBR mice have elevated humoral immunity, in that they have naturally high serum IgG levels and generate
Mohammad Nizam Uddin +6 more
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