Results 31 to 40 of about 1,435 (170)

Epitranscriptomics of Mammalian Mitochondrial Ribosomal RNA

open access: yesCells, 2020
Modified nucleotides are present in all ribosomal RNA molecules. Mitochondrial ribosomes are unique to have a set of methylated residues that includes universally conserved ones, those that could be found either in bacterial or in archaeal/eukaryotic ...
Ivan Laptev, Olga Dontsova, Petr Sergiev
doaj   +1 more source

RNA m6A Alterations Induced by Biomineralization Nanoparticles: A Proof-of-Concept Study of Epitranscriptomics for Nanotoxicity Evaluation

open access: yesNanoscale Research Letters, 2022
Although various strategies have been included in nanotoxicity evaluation, epitranscriptomics has rarely been integrated into this field. In this proof-of-concept study, N6-methyladenosine (m6A) changes of mRNA in HEK293T cells induced by three bovine ...
Jinbin Pan   +6 more
doaj   +1 more source

Sixth European seminar in virology on virus\u2013host interaction at single cell and organism level [PDF]

open access: yes, 2018
The 6th European Seminar in Virology (EuSeV) was held in Bertinoro, Italy, 22\u201324 June 2018, and brought together international scientists and young researchers working in the field of Virology.
Pal\uf9, Giorgio   +4 more
core   +1 more source

Current Status of Epitranscriptomic Marks Affecting lncRNA Structures and Functions [PDF]

open access: yes, 2022
Long non-coding RNAs (lncRNAs) belong to a class of non-protein-coding RNAs with their lengths longer than 200 nucleotides. Most of the mammalian genome is transcribed as RNA, yet only a small percent of the transcribed RNA corresponds to exons of ...
Bishop, Alexander J. R.   +3 more
core   +2 more sources

Epitranscriptomic N6-Methyladenosine Profile of SARS-CoV-2-Infected Human Lung Epithelial Cells

open access: yesMicrobiology Spectrum, 2023
N6-methyladenosine (m6A) is a dynamic posttranscriptional RNA modification that plays an important role in determining transcript fate. The functional consequence of m6A deposition is dictated by a group of host proteins that specifically recognize and ...
Stacia Phillips   +6 more
doaj   +1 more source

High-throughput identification of C/D box snoRNA targets with CLIP and RiboMeth-seq [PDF]

open access: yes, 2016
High-throughput sequencing has greatly facilitated the discovery of long and short non-coding RNAs (ncRNAs), which frequently guide ribonucleoprotein complexes to RNA targets, to modulate their metabolism and expression.
Gumienny, Rafal   +6 more
core   +1 more source

Regulatory Mechanisms of the RNA Modification m6A and Significance in Brain Function in Health and Disease

open access: yesFrontiers in Cellular Neuroscience, 2021
RNA modifications have emerged as an additional layer of regulatory complexity governing the function of almost all species of RNA. N6-methyladenosine (m6A), the addition of methyl groups to adenine residues, is the most abundant and well understood RNA ...
Justine Mathoux   +5 more
doaj   +1 more source

The Arabidopsis epitranscriptome

open access: yesCurrent Opinion in Plant Biology, 2015
The most prevalent internal modification of plant messenger RNAs, N(6)-methyladenosine (m(6)A), was first discovered in the 1970s, then largely forgotten. However, the impact of modifications to eukaryote mRNA, collectively known as the epitranscriptome, has recently attracted renewed attention.
Fray, Rupert G., Simpson, Gordon G.
openaire   +3 more sources

A panoramic view of RNA modifications: exploring new frontiers

open access: yesGenome Biology, 2018
Meeting report on the Cold Spring Harbor Asia conference on RNA Modifications and Epitranscriptomics, held in Suzhou, China, 13–17 November, 2017.
Zijun Zhang   +3 more
doaj   +1 more source

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