ERN1 modifies the effect of glutamine deprivation on tumor growth related factors expression in U87 glioma cells [PDF]
The Ukrainian Biochemical Journal, 2018 The expression of a subset of genes encoding important tumor growth related factors in U87 glioma cells with ERN1 (endoplasmic reticulum to nucleus signaling 1) loss of function as well as upon glutamine deprivation was studied.
O. H. Minchenko +5 more
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Біологічні студії, 2011 The main molecular components of circadian clock system are proteins which play a significant role in the control of both metabolism and malignant tumor growth.
L. L. Karbovskyi +4 more
doaj +1 more source
TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation [PDF]
, 2016 Summary - Significant insights into disease pathogenesis have been gleaned from population-level genetic studies; however, many loci associated with complex genetic disease contain numerous genes, and phenotypic associations cannot be assigned ...
Bhan, Atul K. +16 more
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ATF4 links ER stress with reticulophagy in glioblastoma cells [PDF]
, 2020 Selective degradation of the endoplasmic reticulum (ER; reticulophagy) is a type of autophagy involved in the removal of ER fragments. So far, amino acid starvation as well as ER stress have been described as inducers of reticulophagy, which in turn ...
Covarrubias-Pinto, Adriana +11 more
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The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells [PDF]
, 2015 By monitoring the fragmentation of a GST-BHMT (a protein fusion of glutathionine S-transferase N-terminal to betaine-homocysteine S-methyltransferase) reporter in lysosomes, the GST-BHMT assay has previously been established as an endpoint, cargo-based ...
Sheng Zhang +3 more
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ER stress in obesity pathogenesis and management. [PDF]
, 2021 Given the unprecedented global pandemic of obesity, a better understanding of the etiology of adiposity will be necessary to ensure effective management of obesity and related complications.
Ajoolabady, Amir +8 more
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IRE1-XBP1 Pathway of the Unfolded Protein Response Is Required during Early Differentiation of C2C12 Myoblasts [PDF]
, 2019 ArticleInternational Journal of Molecular Sciences. 21(1): 182.
Arai, Wataru +6 more
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The effects of graded levels of calorie restriction : XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome [PDF]
, 2017 We would like to acknowledge the BSU staff for their invaluable help with caring for the animals.Peer reviewedPublisher ...
Chen, Luonan +10 more
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Endocrine Regulations, 2020 Objective. The aim of this investigation was to study the expression of genes encoding cAMP-activated protein kinase catalytic and regulatory A subunits (PRKACA and PRKAR1A) and related proteins such as cAMP-dependent protein kinase inhibitors A and G ...
Ratushna Oksana O.
doaj +1 more source
Targeting mitochondrial stress with Szeto-Schiller 31 prevents experimental abdominal aortic aneurysm : Crosstalk with endoplasmic reticulum stress [PDF]
, 2023 Mitochondrial dysfunction and inflammation contribute to a myriad of cardiovascular diseases. Deleterious crosstalk of mitochondria and persistent endoplasmic reticulum (ER) stress triggers oxidative stress, which is involved in the development of ...
Navas Madroñal, Miquel +10 more
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