Genetic variation of ERN1 and susceptibility to type 2 diabetes [PDF]
To investigate the relationship between common single nucleotide polymorphisms (SNPs) of the ERN1 gene and T2D ...
Klyosova, E. Yu.
core +1 more source
The effects of ERN1 on gene expression during early rhizobial infection in Lotus japonicus [PDF]
Legumes develop root nodules in association with compatible rhizobia to overcome nitrogen deficiency. Rhizobia enter the host legume, mainly through infection threads, and induce nodule primordium formation in the root cortex.
Akiko Oda +7 more
core +1 more source
Hypoxic regulation of MYBL1, MEST, TCF3, TCF8, GTF2B, GTF2F2 and SNAI2 genes expression in U87 glioma cells upon IRE1 inhibition [PDF]
We investigated the impact of IRE1/ERN1 (inositol requiring enzyme 1/endoplasmic reticulum to nucleus signaling 1) knockdown on hypoxic regulation of the expression of a subset of proliferation and migration-related genes in U87 glioma cells.
O. H. Minchenko +3 more
doaj +1 more source
Inhibition of ERN1 signaling enzyme affects hypoxic regulation of the expression of E2F8, EPAS1, HOXC6, ATF3, TBX3 and FOXF1 genes in U87 glioma cells [PDF]
Hypoxia as well as the endoplasmic reticulum stress are important factors of malignant tumor growth and control of the expression of genes, which regulate numerous metabolic processes and cell proliferation.
O. H. Minchenko +5 more
doaj +1 more source
Legumes develop root nodules in association with compatible rhizobia to overcome nitrogen deficiency. Rhizobia enter the host legume, mainly through infection threads, and induce nodule primordium formation in the root cortex.
Takashi Goto (6177368) +7 more
core +1 more source
THE MULTIFACETED ROLE OF ENDOPLASMIC RETICULUM STRESS IN THE REGULATION OF GENE EXPRESSION IN NORMAL ASTROCYTES AND GLIOBLASTOMA CELLS [PDF]
Aim. To determine the role of the endoplasmic reticulum (ER) in regulating gene expression in normal astrocytes and glioblastoma cells under the application of carbon nanoparticles as anti-tumor agents. Methods.
O.V. Rudnytska
doaj +1 more source
Metabolomics in ERN1 and ERN1-DeltaK liver samples
Data related to this article: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics Samples are: ERN1 and ERN1-DeltaK liver samples (4 per group, also named ...
Carreras-sureda, A (via Mendeley Data)
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Abstract figure legend LIGHT is a mutual mediator of intestinal and oesophageal fibroblast inflammation with common as well as tissue‐specific effects. Hydroxylase inhibitors can selectively suppress inflammatory factors in both cell types, albeit targeting different signalling pathways.
Cian M. Ohlendieck +13 more
wiley +1 more source
Scientific achievements of the Department of Molecular Biology in understanding stress-dependent mechanisms of glioma growth [PDF]
Since 2005, the Department of Molecular Biology has initiated research aimed at solving key problems in biochemistry and molecular biology, with an emphasis on elucidating the molecular basis of malignant tumor growth and the mechanisms of hypoxic ...
O. H. Minchenko +3 more
doaj +1 more source
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei +26 more
wiley +1 more source

