Results 91 to 100 of about 5,605 (194)

Ficolin-2 a newmarker for severity of liver inflammation in patients with chronic hepatitis C [PDF]

The Egyptian Journal of Hospital Medicine, 2018
Background: ficolin-2 is a kind of human serum complement lectin with a structure similar to mannan-binding lectin (MBL) and it has been implicated in innate immunity. Recent studies have shown that complement pathway activation may contribute to hepatitis. However, the relationship between ficolin-2 and viral hepatitis remains largely elusive.
Abd El Monem M. Barrak, Hesham E. Lashin, Mahmoud M. Metwally, Nabil I. Abd El-Rahman   +3 more
openaire   +1 more source

Inherited deficiency of the initiator molecules of the lectin-complement pathway [PDF]

, 2010
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)The complement system is an important immune system. Its activation results in membranolytic elimination of microbes and opsonization.
Björn Rúnar Lúðvíksson, Helga Bjarnadóttir   +1 more
core  

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source

Studies on the release of neutrophil extracellular traps and IFN-γ as part of the innate immune response to Aspergillus fumigatus and on the fungal stress response via the hybrid sensor kinase TcsC [PDF]

, 2012
Aspergillus fumigatus is a saprophytic mold that naturally inhabits the soil. Asexual reproduction yields hardy conidia that circulate in the air and are inhaled daily by humans.
McCormick, Allison
core  

Complement Hyperactivation Is Mediated by Alternative and Lectin Pathways During Early Phase of Severe Vaccination‐Omicron BA.5 Infection

Journal of Medical Virology, Volume 98, Issue 3, March 2026.
ABSTRACT Complement temporal activation kinetics, activation pathways, and their relationship with thromboinflammation and antibody responses in severe vaccination‐COVID‐19 remains unclear. Based on a vaccinated‐infected cohort, we analyzed complement immune responses across mild to critical COVID‐19 cases by a dynamic model.
Jinpeng Cao, Gang Yang, Tingting Cui, Jian Qin, Deyi Huang, Shiqin Jin, Xiaoyun Yang, Mingzhu Huang, Xiaoling Su, Siyi Liu, Yingjiao Xia, Shidong Deng, Chengna Luo, Zhuxiang Zhao, Yunhui Zhang, Nanshan Zhong, Zhongfang Wang   +16 more
wiley   +1 more source

Non-synonymous polymorphisms in the FCN1 gene determine ligand-binding ability and serum levels of M-ficolin.

PLoS ONE, 2012
BackgroundThe innate immune system encompasses various recognition molecules able to sense both exogenous and endogenous danger signals arising from pathogens or damaged host cells.
Christian Gytz Ammitzbøll, Troels Rønn Kjær, Rudi Steffensen, Kristian Stengaard-Pedersen, Hans Jørgen Nielsen, Steffen Thiel, Martin Bøgsted, Jens Christian Jensenius   +7 more
doaj   +1 more source

Insufficient serum L-ficolin is associated with disease presence and extent of pulmonary Mycobacterium avium complex disease

Respiratory Research, 2019
Background The incidence of infectious disease caused by nontuberculous mycobacteria is increasing worldwide. Pulmonary Mycobacterium avium complex (MAC) disease is difficult to treat with chemotherapy, and its mechanism of infection, infection route ...
Tomofumi Kobayashi, Koji Kuronuma, Atsushi Saito, Kimiyuki Ikeda, Shigeru Ariki, Atsushi Saitou, Mitsuo Otsuka, Hirofumi Chiba, Satoshi Takahashi, Motoko Takahashi, Hiroki Takahashi   +10 more
doaj   +1 more source

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, Volume 13, Issue 10, 18 February 2026.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source

Glycobiology of cell death: when glycans and lectins govern cell fate [PDF]

, 2013
Although one typically thinks of carbohydrates as associated with cell growth and viability, glycosylation also has an integral role in many processes leading to cell death.
A Büssing, A Shiratsuchi, A Sturm, AF Carlin, AF Swindall, B Brandt, BE Britigan, BN Stillman, C Lazar, C Villeneuve, C Zhu, CA Gabel, CF Brewer, D Paclik, E Cao, E Charlier, E Duvall, E Rapoport, EM Rapoport, F Bernerd, F Dall’Olio, F Gu, F Yu, FA Barr, FT Liu, G A Rabinovich, G Ion, G Majai, G Yogalingam, GA Rabinovich, GA Rabinovich, GA Rabinovich, GA Rabinovich, GA Rabinovich, GA Rabinovich, GC Fernández, GD Griffiths, GR Vasta, H Ise, H Sano, H Sano, HM Meesmann, HP Hahn, I Bournazou, I Kuwabara, JA Fulcher, JD Hernandez, JD Marth, JF Kerr, JH Lin, JT Nguyen, K Kollmann, K Lauber, K Moriwaki, K Moriwaki, K Suzuki, KE Pace, KW Wagner, L Eshkar Sebban, LA Earl, LC Paessens, LH Lu, LL Fu, M Cohen, M Dias-Baruffi, M Molinari, M Pang, M Rangachari, MA Toscano, MC Maiuri, ME Peter, ML Litvack, MM Fuster, MM Weck, MU Hutchins, N Maugeri, N Mazurek, N Mazurek, N Mazurek, N Oka, N Sharon, NB Caberoy, OM Shatnyeva, OT Keppler, P Desharnais, P Matarrese, P Schneider, P Smits, R G Lichtenstein, R Hanayama, R Hanayama, RA Lockshin, RG Morris, RS Maag, RY Yang, S Arur, S Eda, S Gupta, S Li, S Mukherjee, S Toda, S Wesselborg, SC Starossom, SJ Van Dyken, SJ Van Vliet, SR Stowell, SR Stowell, T Fukumori, T Fukumori, TL Schagat, TL Thurston, V Wells, VA Fadok, VM Abrahams, X Li, Y Kashio, Y Oda, Y Wang, Y Watanabe, Y Watanabe, Y Zhuo, YJ Lee, Z Liu, ZN Oltvai   +123 more
core   +2 more sources

Spatial heterogeneity in microglia‐complement crosstalk: Implications for synaptic pruning in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized by synaptic loss, as a key pathological feature in its early stages. Recent studies have highlighted the central role of microglia–complement interactions in synaptic pruning.
Qiuyan Ye, Wei Gao, Jiaping Feng, Xue Li, Jianhui Li, Fengge Yang, Linqing Li, Mingsheng Zi, Xinkai Wu, Hainan Gao, Honglin Li   +10 more
wiley   +1 more source