Detection of serum concentration of Il-12 in H.pylori infected people comparing to healthy one [PDF]
Introduction: The prevalence ratio of H. pylori infection in developed and developing countries is 30% and 80% respectively. Dominant Immune response in H.
اتحاد, غلامحسین +3 more
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Vaccination of Rhesus Macaques with a Recombinant Measles Virus Expressing Interleukin-12 Alters Humoral and Cellular Immune Responses [PDF]
, 2017 Lack of a vaccine for infants and immunosuppression after infection are problems associated with measles virus (MV). Because interleukin (IL)-12 has been used successfully as a vaccine adjuvant and because inhibition of IL-12 expression has been ...
Adams, Robert J. +6 more
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Morphological and Functional Characterization of IL-12Rβ2 Chain on Intestinal Epithelial Cells: Implications for Local and Systemic Immunoregulation [PDF]
, 2018 Interaction between intestinal epithelial cells (IECs) and the underlying immune systems is critical for maintaining intestinal immune homeostasis and mounting appropriate immune responses.
Bacon +33 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter +17 more
wiley +1 more source
Riboswitch-controlled IL-12 gene therapy reduces hepatocellular cancer in mice
Frontiers in ImmunologyHepatocellular carcinoma (HCC) and solid cancers with liver metastases are indications with high unmet medical need. Interleukin-12 (IL-12) is a proinflammatory cytokine with substantial anti-tumor properties, but its therapeutic potential has not been ...
Matthias J. Düchs +15 more
doaj +1 more source
IL-12-dependent innate immunity arrests endothelial cells in G0-G1 phase by a p21(Cip1/Waf1)-mediated mechanism. [PDF]
, 2012 Innate immunity may activate paracrine circuits able to entail vascular system in the onset and progression of several chronic degenerative diseases. In particular, interleukin (IL)-12 triggers a genetic program in lymphomononuclear cells characterized ...
Alvaro M +10 more
core +1 more source
Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes
Pediatric Blood &Cancer, EarlyView.ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles +4 more
wiley +1 more source
Role of IL-12 in T cell activation in old mice [PDF]
, 2008 The cytokine interleukin-12 (IL-12) has potent biological activities and is particularly important for the synergistic activation of CD4+ and CD8+ T cells to secrete IFN-γ during an antigen specific exposure.
Davis, Craig
core
Construction and characterization of H5N1-recombinant fowlpox viruses co-expressing host cytokines [PDF]
, 2011 Possessing a large double stranded DNA genome up to 300 kb, fowlpox virus (FWPV) has been developed to express avian influenza virus (AIV) antigens since the late 1980s. A more advanced approach would be to coexpress host cytokines from such recombinants.
Abdul Razak, Mariatulqabtiah +1 more
core +1 more source
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source