Results 91 to 100 of about 82,847,056 (224)

IL-12/IL-10 mRNA expression in RTS-11 cell line infected with P. salmonis.

, 2016
Relative mRNA expression of IL-12 and IL-10 in RTS-11 cell line infected with P. salmonis for 1, 6, 12, 24, 36, 48, 60, and 72 h. mRNA expression is expressed as a fold-change over the control (0 h).
Fernando A. Gomez (3207180), Claudio A. Álvarez (3207186), Ramón Ramírez (3207183), Luis Mercado (685871), Sergio H. Marshall (163537)   +4 more
core   +1 more source

In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines [PDF]

, 2002
We show that a combination of the immunosuppressive drugs, vitamin D3 and Dexamethasone, induced human and mouse naive CD4(+) T cells to differentiate in vitro into regulatory T cells.
Hawrylowicz, C.M., Robert L. Coffman, André Boonstra, Richards, David F, Richards, D.F., Catherine M. Hawrylowicz, Savelkoul, H.F.J., Savelkoul, HFJ (Huub), Crain, Chad, Anne O'Garra, O' Garra, A, Coffman, R.L., O'Garra, Anne, Cua, D.J., Chad Crain, Cua, DJ, Huub F. Savelkoul, Coffman, RL, Waal-Malefyt, R., de, Cua, Daniel J, Savelkoul, Huub F, Barrat, Franck J, de Waal-Malefyt, René, de Waal-Malefyt, R, Hawrylowicz, Catherine M; id_orcid, Crain, C., Barrat, FJ, Barrat, F.J., Crain, C, Coffman, Robert L, Boonstra, P.A., Daniel J. Cua, Hawrylowicz, CM, Franck J. Barrat, David F. Richards, O'Garra, A., René de Waal-Malefyt, Richards, DF, Boonstra, Andre   +38 more
core   +1 more source

SECRETION OF IL-12, IL-27 BY MONONUCLEAR LEUKOCYTES AND EXPRESSION OF THEIR RECEPTORS ON T-LYMPHOCYTES IN CONDITIONS OF DIRECTED CELL INDUCTION IN VITRO IN PULMONARY TUBERCULOSIS

Медицинская иммунология, 2014
The article presents the results of studies concerning secretion of cytokines belonging to interleukin 12 family, i.e., IL-12р70, IL-12р40, IL-12р35 and IL-27 in mononuclear blood leukocytes, as well as expression of their specific receptors on T ...
I. E. Esimova, O. I. Urazova, V. V. Novitskiy, R. R. Khasanova, O. V. Filinyuk   +4 more
doaj   +1 more source

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres, Cristina Tarango, Ashley Childress, Chunyan Liu, Evan Thomas, Jennifer Pomales, Eric S. Mullins   +6 more
wiley   +1 more source

mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy [PDF]

, 2023
Interleukin-12 (IL-12) gene transfer enhances the therapeutic potency of adoptive T cell therapies. We previ-ously reported that transient engineering of tumor-specific CD8 T cells with IL-12 mRNA enhanced their sys-temic therapeutic efficacy when ...
Bolaños, E. (Elixabet), Garasa, S. (Saray), Olivera, I. (Irene), Álvarez-Rodríguez, M. (Maite), Fernandez-Sanmamed, M. (Miguel), Cirella, A. (Assunta), Guedan, S. (Sonia), Berraondo, P. (Pedro), Rabinovich, G.A. (Gabriel A.), Mariño, K. (Karina), González-Gomariz, J. (José), Egea, J. (Josune), González-Vaz, J. (Javier), Etxeberria, I. (Iñaki), Teijeira, A. (Álvaro), Luri-Rey, C. (Carlos), Hervas-Stubbs, S. (Sandra), Eguren-Santamaría, I. (Iñaki), Melero, I. (Ignacio)   +18 more
core  

The level of IL-12, IL-10, IL-4, and MMP-13 in cutaneous leishmaniasis patients

Medical Journal of Babylon
Background: Cutaneous leishmaniasis (CL) is a dermatological condition that arises due to the presence of protozoan parasites. The disease disproportionately impacts those residing in economically disadvantaged regions and is closely linked to factors ...
Abrar Kareem Dhari, Ali Mohammed Abed, Suha Maher Abed   +2 more
doaj   +1 more source

Analysis of Swine Conventional Dendritic Cells, DEC205⁺CD172a^+/−CADM1⁺, from Blood and Spleen in Response to PRRSV and PEDV

Viruses, 2019
Conventional dendritic cells (cDCs) cannot be infected by porcine reproductive and respiratory syndrome virus (PRRSV) but respond to infection via cytokine production, indicating a possible role in initiation/regulation of the immune response against ...
Héctor Parra-Sánchez, Lorena Bustamante-Córdova, Mónica Reséndiz, Verónica Mata-Haro, Araceli Pinelli-Saavedra, Jesús Hernández   +5 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Anti-tumor effect of tumor specific replicating adenovirus expressing IL-12 and IL-18

, 2006
의과학과/석사[한글]암에 대한 면역 치료법은 부작용이 심각한 기존의 방사선 요법 , 항암화학 요법과는 달리 우리 몸의 면역 체계를 활성화시킴으로서 암 세포만을 특이적으로 제거하는데 그 목적이 있다. 하지만, 암 세포들은 여러 가지 전략을 사용하여 면역 체계를 교묘히 피해가며, 설사 면역 체계가 활성화 되었더라도 활성화된 항종양 면역 반응으로부터 도피할 수 있는 능력 또한 갖고 있기 때문에 항암 면역 치료에 많은 한계를 드러내고 있다. 따라서 이와 같이
최일규
core  

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source