Results 101 to 110 of about 82,847,056 (224)
Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL [PDF]
Recently, gene-based cytokine treatment has been actively pursued as a new promising approach in treating cancer. In an effort to augment the efficiency of antitumor effect by cytokine-mediated immunotherapy, we selected both interleukin (IL)-12 and 4 ...
윤채옥 +15 more
core +1 more source
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Local expression of IL-12, IL-23, IFN-γ, and TNF-α in vivo.
Tumor tissue was obtained at 7 days after the first viral treatment. ELISA was performed to estimate the level of IL-12 (a), IL-23 (b), IFN-γ (c), and TNF-α (d) in tumor tissues. Experiments were carried out in triplicate and repeated three times.
Eonju Oh (430119) +4 more
core +1 more source
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
wiley +1 more source
Opposing roles for IL-23 and IL-12 in maintaining occult cancer in an equilibrium state
Fulltext embargoed for: 12 months post date of publicationCancer immunoediting, the process by which the immune system controls tumor growth and shapes tumor immunogenicity, consists of 3 stages: elimination, equilibrium, and escape.
Duret, H +6 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
B6 mice were treated with IL-12 cDNA alone (black circle), IL-12+IL-18 cDNA (open circle) or low IL-12 cDNA (0,5 µg) 2 days prior to administration of a high amount of IL-12 cDNA (5 µg) (black square).
Natalia S. Baez (528842) +6 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Il capitolo presenta i risultati di un questionario rivolto agli intermediari bancari italiani che operano nel comparto del microcredito finalizzato ad indagare lo stato dell'arte di questo business (margini prodotti, modalità di valutazione del rischio,
PORRETTA, Pasqualina
core
Objetivos. Evaluar el efecto inmunomodulador del extracto estandarizado (5,03%, alcaloides oxindólicos pentacíclicos) de Uncaria tomentosa (UT-POA) sobre el inmunofenotipo de células dendríticas (DC) y IL-12/Th1/Th2/Th17 en pacientes con cáncer de mama ...
César Núñez +5 more
doaj +2 more sources

