Results 11 to 20 of about 1,721,070 (243)
Journal for ImmunoTherapy of Cancer, 2018 Interleukin-12 (IL-12) is a promising candidate for cancer immunotherapy because of its ability to activate a number of host immune subsets that recognize and destroy cancer cells.
Ian Lai +6 more
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The influence of sepsis as a complication after trauma on immune response to injury [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2011 Introduction. Mortality rate in trauma complicated with sepsis is exceeding 50%. Outcome is not determined only by infection or trauma, but also by the intensity of immuno-inflammatory response. Objective.
Šurbatović Maja +4 more
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Frontiers in Immunology, 2016 The interleukin (IL)-6/IL-12 family cytokines have pleiotropic functions and play critical roles in multiple immune responses. This cytokine family has very unique characteristics in that they are composed of two distinct subunits forming a heterodimer ...
Hideaki Hasegawa +5 more
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The power and pitfalls of IL-12 [PDF]
Blood, 2012 In this issue of Blood, Pegram and colleagues describe the ability to improve adoptive T-cell therapies by engineering T cells to secrete the potent proinflammatory cytokine IL-12.1 These exciting findings significantly extend previous observations made in a murine melanoma model targeting naturally occurring tumor antigens.2 ...
Sid P, Kerkar, Nicholas P, Restifo
openaire +2 more sources
Biochemical, Molecular and Histopathological changes of rheumatoid arthritis induced experimentally in rats [PDF]
Benha Veterinary Medical Journal, 2023 Complete Freund's adjuvant (CFA) is a mixture of dessicated mycobacterium in mannide monooleate and paraffin oil that causes tissue death, lesions, and inflammation.
Nihal Amer +3 more
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Biotechnology & Biotechnological Equipment, 2016 Hashimoto's thyroiditis (HT) is an organ-specific, mainly Th1 autoimmune disorder. New evidence has accumulated for involvement of Treg-produced cytokines.
Julieta Gerenova +2 more
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Interleukin-12 family cytokines and sarcoidosis
Frontiers in Pharmacology, 2014 Sarcoidosis is a systemic granulomatous disease predominantly affecting the lungs. It is believed to be caused by exposure to pathogenic antigens in genetically susceptible individuals but the causative antigen has not been identified.
Sabine eRingkowski +3 more
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Development of Tumor Cell-Based Vaccine with IL-12 Gene Electrotransfer as Adjuvant
Vaccines, 2020 Tumor cell-based vaccines use tumor cells as a source of tumor-associated antigens. In our study, we aimed to develop and test a tumor vaccine composed of tumor cells killed by irradiation combined with in vivo interleukin-12 gene electrotransfer as an ...
Tinkara Remic +4 more
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Cytokine Secretion in Macrophages: SNAREs, Rabs and Membrane Trafficking.
Frontiers in Immunology, 2014 Macrophages have the capacity to rapidly secrete a wide range of inflammatory mediators that influence the development and extent of an inflammatory response.
Rachael Zoe Murray, Jennifer L Stow
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Медицинская иммунология, 2022 Current literature contains a large amount of data on the modifying effect of cold stress on the functions of immune cell system, in particular, on the secretion of cytokines by the cells of innate and adaptive immunity, mRNA expression.
I. L. Sharav’eva, S. V. Gein
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