Results 11 to 20 of about 8,108 (168)
Advances in MICA genotyping: characterization of 406 novel alleles and their frequencies in multiple populations [PDF]
Frontiers in ImmunologyIn 2020, we reported MICA allele frequencies from a cohort of over one million German individuals. This study identified MICA*008 (42%), MICA*002 (12%), and MICA*009 (9%) as the most common MICA alleles at protein resolution.
Viviane Albrecht +8 more
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The evolutionary history of IGKC in mammals reveals ancient duplications and remarkable divergence in lagomorphs [PDF]
Frontiers in ImmunologyBackgroundThe Immunoglobulin Kappa Constant (IGKC) gene encodes the constant region of the immunoglobulin kappa light chain, a crucial component of antibodies.
Ana Pinheiro +10 more
doaj +2 more sources
From benchmarking alignment of genome assemblies to IMGT annotation: the paradigm of the bovine Bos taurus T cell receptor (TRG) locus [PDF]
BMC GenomicsT cell receptors (TR) are essential components of the adaptive immune system, typically classified into αβ and γδ types. In humans and mice, αβ T cells predominate, with γδ T cells comprising only a small percentage of the total T cell population.
Hao Zhou +5 more
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Three-Dimensional Modeling of Camelus dromedarius T Cell Receptor Gamma (TRG)_Delta (TRD)/CD1D Complex Reveals Different Binding Interactions Depending on the TRD CDR3 Length [PDF]
AntibodiesBackground: In the adaptive immune response of the dromedary (Camelus dromedarius, Camdro), the T cell receptor (TR) repertoire of the gamma–delta (γδ) T cells is unusually diversified both by somatic hypermutation in rearranged TR gamma (TRG) and delta (
Salvatrice Ciccarese +4 more
doaj +2 more sources
Nucleic Acids Research, 2009 It is 10 years since the IMGT/HLA database was released, providing the HLA community with a searchable repository of highly curated HLA sequences. The HLA complex is located within the 6p21.3 region of human chromosome 6 and contains more than 220 genes of diverse function.
James Robinson +6 more
openaire +2 more sources
Nucleic Acids Research, 2012 It is 14 years since the IMGT/HLA database was first released, providing the HLA community with a searchable repository of highly curated HLA sequences. The HLA complex is located within the 6p21.3 region of human chromosome 6 and contains more than 220 genes of diverse function.
James Robinson +5 more
openaire +3 more sources
Nucleic Acids Research, 2010 It is 12 years since the IMGT/HLA database was first released, providing the HLA community with a searchable repository of highly curated HLA sequences. The HLA complex is located within the 6p21.3 region of human chromosome 6 and contains more than 220 genes of diverse function.
James Robinson +5 more
openaire +2 more sources
Biomolecules, 2022 IMGT®, the international ImMunoGeneTics information system®, created in 1989, by Marie-Paule Lefranc (Université de Montpellier and CNRS), marked the advent of immunoinformatics, a new science which emerged at the interface between immunogenetics and ...
Marie-Paule Lefranc, Gérard Lefranc
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IMGT, the international ImMunoGeneTics database [PDF]
Nucleic Acids Research, 1998 IMGT, the international ImMunoGeneTics database, freely available at http://imgt.cines.fr:8104, was created in 1989 at the Université Montpellier II, CNRS, Montpellier, France, and is a high quality integrated information system specialising in immunoglobulins, T cell receptors and major histocompatibility complex molecules of human and other ...
Marie-Paule Lefranc +8 more
openaire +8 more sources
Pharmaceuticals, 2020 Because chemotherapeutic drugs are often associated with serious side effects, the central topic in modern drug delivery is maximizing the localization of drugs at the target while minimizing non-specific drug interactions at unwanted regions. To address
Daehyun Kim +8 more
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