From IMGT-ONTOLOGY to IMGT/LIGMotif: the IMGT® standardized approach for immunoglobulin and T cell receptor gene identification and description in large genomic sequences [PDF]
Background The antigen receptors, immunoglobulins (IG) and T cell receptors (TR), are specific molecular components of the adaptive immune response of vertebrates.
Lefranc Marie-Paule +2 more
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IMGT, the international ImMunoGeneTics database [PDF]
IMGT, the international ImMunoGeneTics database, is an integrated database specializing in immunoglobulins, T-cell receptors (TcR) and major histocompatibility complex (MHC) of all vertebrate species, initiated and co-ordinated by Marie-Paule Lefranc, CNRS, Montpellier II University, Montpellier, France (lefranc@ligm.crbm.cnrs-mop.fr).
Marie-Paule Lefranc +9 more
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IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex [PDF]
The IMGT/HLA database (http://www.ebi.ac.uk/imgt/hla) has provided a centralized repository for the sequences of the alleles named by the WHO Nomenclature Committee for Factors of the HLA System for the past four years. Since its initial release the database has grown and is the primary source of information for the study of sequences of the human ...
James Robinson +7 more
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IMGT-ONTOLOGY is the ontology for immunogenetics and immunoinformatics. IMGT-ONTOLOGY, created to manage the complexity of immunogenetics knowledge, is the first ontology and global reference in the domain. IMGT-ONTOLOGY has been essential for the creation in 1989 of IMGT®, the international ImMunoGeneTics information system® (http://www.imgt.org ...
Lefranc, Marie-Paule +1 more
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IMGT/LIGM-DB, the IMGT(R) comprehensive database of immunoglobulin and T cell receptor nucleotide sequences [PDF]
IMGT/LIGM-DB is the IMGT comprehensive database of immunoglobulin (IG) and T cell receptor (TR) nucleotide sequences from human and other vertebrate species. It was created in 1989 by LIGM, Montpellier, France and is the oldest and the largest database of IMGT.
Giudicelli, Véronique +6 more
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IMGT/HighV-QUEST Statistical Significance of IMGT Clonotype (AA) Diversity per Gene for Standardized Comparisons of Next Generation Sequencing Immunoprofiles of Immunoglobulins and T Cell Receptors. [PDF]
The adaptive immune responses of humans and of other jawed vertebrate species (gnasthostomata) are characterized by the B and T cells and their specific antigen receptors, the immunoglobulins (IG) or antibodies and the T cell receptors (TR) (up to 2.1012
Safa Aouinti +4 more
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Immunoglobulins or Antibodies: IMGT® Bridging Genes, Structures and Functions
IMGT®, the international ImMunoGeneTics® information system founded in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), marked the advent of immunoinformatics, a new science at the interface between immunogenetics and bioinformatics. For
Marie-Paule Lefranc, Gérard Lefranc
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IMGT/mAb-KG: the knowledge graph for therapeutic monoclonal antibodies [PDF]
IntroductionTherapeutic monoclonal antibodies (mAbs) have demonstrated promising outcomes in diverse clinical indications, including but not limited to graft rejection, cancer, and autoimmune diseases lately.Recognizing the crucial need for the ...
Gaoussou Sanou +6 more
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Immunogenetics Sequence Annotation: the Strategy of IMGT based on IMGT-ONTOLOGY.
IMGT, the international ImMunoGeneTics information system((R))(http://imgt.cines.fr) created in 1989, by the Laboratoire d'ImmunoGénétique Moléculaire (LIGM), Université Montpellier II and CNRS, Montpellier, France, is a high quality integrated information system, secialized in immunoglobulins (IG), T cell receptors (TR), major histocompatibility ...
Giudicelli, Véronique +3 more
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IMGT-KG: A Knowledge Graph for Immunogenetics
International audienceKnowledge graphs are emerging as one of the most popular means for data federation, transformation, integration and sharing, promising to improve data visibility and reusability.
Gaoussou Sanou +5 more
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