Results 31 to 40 of about 8,108 (168)

IMGT, the international ImMunoGeneTics database [PDF]

Nucleic Acids Research, 2000
IMGT, the international ImMunoGeneTics database (http://imgt.cines. fr:8104 ), is a high-quality integrated database specialising in Immunoglobulins (Ig), T cell Receptors (TcR) and Major Histocompatibility Complex (MHC) molecules of all vertebrate species, created in 1989 by Marie-Paule Lefranc, Université Montpellier II, CNRS, Montpellier, France ...
Manuel Ruiz, Véronique Giudicelli, Chantal Ginestoux, Peter Stoehr, James Robinson, Julia G. Bodmer, Steven G. E. Marsh, Ronald Bontrop, Marc Lemaitre, Gérard Lefranc, Denys Chaume, Marie-Paule Lefranc   +11 more
openaire   +2 more sources

Immunoglobulin (IG) and T cell receptor (TR) genes: IMGT® and the birth and rise of immunoinformatics

Frontiers in Immunology, 2014
IMGT®, the international ImMunoGeneTics information system®, http://www.imgt.org (CNRS and Université Montpellier 2) is the global reference in immunogenetics and immunoinformatics.
Marie-Paule eLefranc
doaj   +1 more source

Immunoglobulins or Antibodies: IMGT^® Bridging Genes, Structures and Functions

Biomedicines, 2020
IMGT®, the international ImMunoGeneTics® information system founded in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), marked the advent of immunoinformatics, a new science at the interface between immunogenetics and bioinformatics. For
Marie-Paule Lefranc, Gérard Lefranc
doaj   +1 more source

Effects of Lipid Shape and Interactions on the Conformation, Dynamics, and Curvature of Ultrasound-Responsive Liposomes

Pharmaceutics, 2022
We perform coarse-grained molecular dynamics simulations of bilayers composed of various lipids and cholesterol at their different ratios. Simulations show that cholesterol-lipid interactions restrict the lateral dynamics of bilayers but also promote ...
Hwankyu Lee, Hyungwon Moon, Hyun-Ryoung Kim   +2 more
doaj   +1 more source

IMGT^® and 30 Years of Immunoinformatics Insight in Antibody V and C Domain Structure and Function

Antibodies, 2019
At the 10th Human Genome Mapping (HGM10) Workshop, in New Haven, for the first time, immunoglobulin (IG) or antibody and T cell receptor (TR) variable (V), diversity (D), joining (J), and constant (C) genes were officially recognized as ‘genes ...
Marie-Paule Lefranc, Gérard Lefranc
doaj   +1 more source

IMGT^® Biocuration and Analysis of the Rhesus Monkey IG Loci

Vaccines, 2022
The adaptive immune system, along with the innate immune system, are the two main biological processes that protect an organism from pathogens. The adaptive immune system is characterized by the specificity and extreme diversity of its antigen receptors.
Viviane Nguefack Ngoune, Morgane Bertignac, Maria Georga, Ariadni Papadaki, Alexandre Albani, Géraldine Folch, Joumana Jabado-Michaloud, Véronique Giudicelli, Patrice Duroux, Marie-Paule Lefranc, Sofia Kossida   +10 more
doaj   +1 more source

Ontology for immunogenetics: the IMGT-ONTOLOGY [PDF]

Bioinformatics, 1999
Abstract Motivation: IMGT, the international ImMunoGene- Tics database (http://imgt.cines.fr:8104), created by M.-P. Lefranc, is an integrated database specializing in antigen receptors (immunoglobulins and T-cell receptors) and major histocompatibility complex (MHC) of all vertebrate species.
Véronique Giudicelli, Marie-Paule Lefranc   +1 more
openaire   +3 more sources

IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB

Frontiers in Immunology, 2020
IMGT®, the international ImMunoGeneTics information system® is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT® marked the advent of immunoinformatics,
Perrine Pégorier, Morgane Bertignac, Imène Chentli, Viviane Nguefack Ngoune, Géraldine Folch, Joumana Jabado-Michaloud, Saida Hadi-Saljoqi, Véronique Giudicelli, Patrice Duroux, Marie-Paule Lefranc, Sofia Kossida   +10 more
doaj   +1 more source

Haplotype Analysis of the T-Cell Receptor Beta (TCRB) Locus by Long-amplicon TCRB Repertoire Sequencing [PDF]

Journal of Immunotherapy and Precision Oncology, 2019
Background: Polymorphism within the human T-cell receptor beta variable (TRBV) gene has been proposed as a risk factor for autoimmune disease and immune-related adverse events (IRAEs) during immunotherapy.
Timothy J Looney, Dzifa Y Duose, Geoffrey Lowman, Elizabeth Linch, Joud Hajjar, Denise Topacio-Hall, Mingxuan Xu, Jianping Zheng, Anas Alshawa, Coya Tapia, Bettzy Stephen, Linghua Wang, Funda Meric-Bernstam, Lauren Miller, Alexander Glavin, Lifeng Lin, Jing Gong, Jeffrey Conroy, Carl Morrison, Fiona Hyland, Aung Naing   +20 more
doaj   +1 more source

IgMAT: immunoglobulin sequence multi-species annotation tool for any species including those with incomplete antibody annotation or unusual characteristics

BMC Bioinformatics, 2023
Background The advent and continual improvement of high-throughput sequencing technologies has made immunoglobulin repertoire sequencing accessible and informative regardless of study species. However, to fully map dynamic changes in polyclonal responses
Daniel Dorey-Robinson, Giuseppe Maccari, John A. Hammond   +2 more
doaj   +1 more source