Results 61 to 70 of about 8,734 (193)

Single‐cell and repertoire profiling reveals immune remodelling in paediatric upper airway: insights from adenoid hypertrophy

Clinical &Translational Immunology, Volume 15, Issue 6, 2026.
Single‐cell and paired V(D)J profiling show that paediatric adenoid hypertrophy features expanded proliferative germinal‐centre B cells with impaired maturation. Abstract Objectives To characterise the immune cellular landscape and paired B‐cell and T‐cell receptor repertoires of hypertrophic adenoids in children with obstructive sleep apnoea.
Chao Wang, Yufei Pan, Xiao Han, Kai Sun, Jing Li, Yuanyuan Lu, Zhenkun Yu   +6 more
wiley   +1 more source

Immunogenetic sequence annotation based on IMGT-ONTOLOGY

, 2009
IMGT/LIGM-DB^1^ is the first and the largest IMGT^®^ database^2^ in which are managed, analysed and annotated more than 136,000 immunoglobulin (IG) and T cell receptor (TR) nucleotide sequences from human and 235 other vertebrate species (April 2009)
Fatena Bellahcene, Véronique Giudicelli, Marie-Paule Lefranc, Géraldine Folch, François Ehrenmann, Joumana Jabado-Michaloud, Géraldine Folch, Patrice Duroux, Joumana Jabado-Michaloud, François Ehrenmann, Véronique Giudicelli   +10 more
core   +1 more source

IMGT/3Dstructure-DB and IMGT/DomainGapAlign: a database and a tool for immunoglobulins or antibodies, T-cell receptors, MHC, IgSF and MhcSF [PDF]

, 2009
IMGT/3Dstructure-DB is the three-dimensional (3D) structure database of IMGT. ®, the international ImMunoGenetics information system. ® that is acknowledged as the global reference in immunogenetics and immunoinformatics.
Ehrenmann, F., Ehrenmann, François, Kaas, Q., Lefranc, M.-P., Lefranc, Marie-Paule   +4 more
core   +1 more source

IMGT-Collier-de-Perles_heavy_chain.zip

, 2021
Supplementary information: 2D antibody structure information (Collier-de-Perles representation) of coronavirus related neutralizing antibodies. (for heavy chain)
Puneet Rawat (11551201)
core   +1 more source

TR Locus Annotation and Characteristics of Rhinolophus ferrumequinum

Frontiers in Immunology, 2021
T-cell antigen receptors (TRs) in vertebrates can be divided into αβ or γδ, encoded by TRA/D, TRG, or TRB loci. TRs play a central role in mammal cellular immunity, which occurs by rearrangement of V, D, J, and C genes in the loci.
Hao Zhou, Long Ma, Longyu Liu, Xinsheng Yao   +3 more
doaj   +1 more source

IGLV3‐21R110 and ibrutinib treatment: Results from the double‐blind, randomized, placebo‐controlled GCLLSG CLL12 trial in early‐stage CLL

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract IGLV3‐21R110 is a point mutation enabling autonomous B‐cell receptor (BCR) signaling in chronic lymphocytic leukemia (CLL). It has been associated with shorter time to first treatment and overall survival, but its effects have not been evaluated in phase 3 clinical trials or in patients treated with Bruton tyrosine kinase inhibitors.
Deyan Y. Yosifov, Sandra Robrecht, Adam Giza, Palash C. Maity, Armin Riecke, Christof Schneider, Billy M. C. Jebaraj, Rashmi P. Dheenadayalan, Hassan Jumaa, Marc Young, Manish Kumar, Lothar Müller, Ursula Vehling‐Kaiser, Michael Eckart, Werner Freier, Björn Schöttker, Tobias Gaska, Marcel Reiser, Anna‐Maria Fink, Kirsten Fischer, Barbara Eichhorst, Michael Hallek, Petra Langerbeins, Eugen Tausch, Stephan Stilgenbauer   +24 more
wiley   +1 more source

IMGT/GeneInfo: T cell receptor gamma TRG and delta TRD genes in database give access to all TR potential V(D)J recombinations

BMC Bioinformatics, 2006
Background Adaptative immune repertoire diversity in vertebrate species is generated by recombination of variable (V), diversity (D) and joining (J) genes in the immunoglobulin (IG) loci of B lymphocytes and in the T cell receptor (TR) loci of T ...
Jouvin-Marche Evelyne, Lefranc Marie-Paule, Chaume Denys, Bellahcene Fatena, Pasqual Nicolas, Hierle Vivien, Baum Thierry-Pascal, Marche Patrice, Demongeot Jacques   +8 more
doaj   +1 more source

Lipid Droplets Are a Physiological Nucleoporin Reservoir

Cells, 2021
Lipid Droplets (LD) are dynamic organelles that originate in the Endoplasmic Reticulum and mostly bud off toward the cytoplasm, where they store neutral lipids for energy and protection purposes.
Sylvain Kumanski, Benjamin T. Viart, Sofia Kossida, María Moriel-Carretero   +3 more
doaj   +1 more source

IMGT-ONTOLOGY for Immunogenetics and Immunoinformatics

, 2004
IMGT, the international ImMunoGeneTics information system® (http://imgt.cines.fr), is a high quality integrated knowledge resource specializing in immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex (MHC) and related proteins of
Thouvenin, Valérie, Combres, Kora, Chaume, Denys, Jabado-Michaloud, Joumana, Duprat, Elodie, Bosc, Nathalie, Lefranc, Gérard, Ginestoux, Chantal, Giudicelli, Véronique, Scaviner, Dominique, Jeanjean, Stéphanie, Guiraudou, Delphine, Protat, Céline, Kaas, Quentin, Monod, Mehdi Yousfi, Pommié, Christelle, Girod, David, Magris, Séverine, Lefranc, Marie-Paule, Folch, Géraldine   +19 more
core   +1 more source

Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming

Frontiers in Immunology, 2019
Immunoglobulins or antibodies are the main effector molecules of the B-cell lineage and are encoded by hundreds of variable (V), diversity (D), and joining (J) germline genes, which recombine to generate enormous IG diversity.
Mats Ohlin, Cathrine Scheepers, Cathrine Scheepers, Martin Corcoran, William D. Lees, Christian E. Busse, Davide Bagnara, Linnea Thörnqvist, Jean-Philippe Bürckert, Katherine J. L. Jackson, Duncan Ralph, Chaim A. Schramm, Nishanth Marthandan, Felix Breden, Jamie Scott, Frederick A. Matsen IV, Victor Greiff, Gur Yaari, Steven H. Kleinstein, Scott Christley, Jacob S. Sherkow, Sofia Kossida, Marie-Paule Lefranc, Menno C. van Zelm, Corey T. Watson, Andrew M. Collins   +25 more
doaj   +1 more source