Results 71 to 80 of about 9,211 (171)

Structural T‐Cell Receptor Analysis in the Age of Machine Learning

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT The development of highly accurate deep learning models for protein structure prediction has transformed the landscape of T‐cell receptor (TCR) structure data, which can now be accessed at repertoire scale. We provide a perspective on the growing field of structural TCR immunoinformatics, summarizing core principles of TCR structural biology ...
Nele P. Quast, Matthew I. J. Raybould, Charlotte M. Deane   +2 more
wiley   +1 more source

HLA Diversity of Over 500,000 Individuals on the DATRI Register Across 18 Regions in India

HLA, Volume 108, Issue 3, September 2026.
ABSTRACT Registries of unrelated stem cell donors can use HLA haplotype frequencies to aid in registry management. DATRI is India's largest registry with over 550,000 donors, with donors in 35 of India's 36 states and union territories. A geographical based analysis on HLA haplotype frequencies has not previously been carried out with an Indian dataset
Michaela Agapiou, Nezih Cereb, Claudia Rutt, Steven G. E. Marsh, James Robinson   +4 more
wiley   +1 more source

IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data

, 2004
IMGT/3Dstructure-DB and IMGT/Structural-Query are a novel 3D structure database and a new tool for immunological proteins. They are part of IMGT, the international ImMunoGenetics information system®, a high-quality integrated knowledge resource ...
Kaas, Q., Ruiz, M., LeFranc, M-P
core   +1 more source

Genetics of Celiac Disease in Southern Brazil: High‐Resolution HLA Haplotypes and Non‐HLA Polymorphisms

HLA, Volume 108, Issue 3, September 2026.
ABSTRACT Celiac disease (CeD) is an autoimmune enteropathy triggered by gluten ingestion in genetically predisposed individuals, who frequently present HLA‐DQ2 or HLA‐DQ8 haplotypes. To examine the genetic architecture of CeD in the admixed South Brazilian population, we sequenced the HLA alleles to high resolution and genotyped 16 non‐HLA ...
Fernanda Vitório da Silva, Valéria Bumiller‐Bini Hoch, Eduardo Delabio Auer, Priscila Ianzen dos Santos, Noah Cline, Luana Caroline Oliveira, Jennifer Elisabeth Hundt, Michael Wittig, Andre Franke, Paul J. Norman, Angelica Beate Winter Boldt   +10 more
wiley   +1 more source

Single Cell and Spatially Resolved Transcriptome and Immune Repertoire of Mouse Thymus During Aging Reveal Immunological Heterogeneity and Direction of Thymic Selection Pressure

Aging Cell, Volume 25, Issue 8, August 2026.
A systemic single‐cell and spatially‐resolved transcriptomics and TCR sequencing analysis across the aging thymus dissects the molecular underpinnings of T cell subset dynamics. The study highlights the shifting proportions and transcriptomic profiles of T cell subsets during aging.
Jialing Fang, Jun Lei, Peng Chen, Zaiqiao Sun, Boxiao He, Yankang Wu, Chonil Paek, Ning Wu, Yafei Huang, ZhaoKui Dan, Hui Zhang, Zijing Xu, Pengcheng Wei, Yongshun Chen, Lei Yin   +14 more
wiley   +1 more source

Deciphering Gorilla gorilla gorilla immunoglobulin loci in multiple genome assemblies and enrichment of IMGT resources

Frontiers in Immunology
Through the analysis of immunoglobulin genes at the IGH, IGK, and IGL loci from four Gorilla gorilla gorilla genome assemblies, IMGT® provides an in-depth overview of these loci and their individual variations in a species closely related to humans.
Chahrazed Debbagh, Géraldine Folch, Joumana Jabado-Michaloud, Véronique Giudicelli, Sofia Kossida, Sofia Kossida   +5 more
doaj   +1 more source

IMGT-Choreography for immunogenetics and immunoinformatics.

, 2005
International audienceIMGT, the international ImMunoGeneTics information system (http://imgt.cines.fr), was created in 1989 at Montpellier, France. IMGT is a high quality integrated knowledge resource specialized in immunoglobulins (IG), T cell receptors
Combres, Kora, Chaume, Denys, Kaas, Quentin, Duprat, Elodie, Lefranc, Gérard, Ginestoux, Chantal, Chastellan, Patrick, Giudicelli, Véronique, Lefranc, Marie-Paule, Clément, Olivier, Coelho, Isabelle   +10 more
core   +1 more source

IMGT-Collier-de-Perles_light_chain.zip

, 2021
Supplementary information: 2D antibody structure information (Collier-de-Perles representation) of coronavirus related neutralizing antibodies. (for light chains)
Puneet Rawat (11551201)
core   +1 more source

Pacific Biosciences Sequencing and IMGT/HighV-QUEST Analysis of Full-Length Single Chain Fragment Variable from an In Vivo Selected Phage-Display Combinatorial Library

Frontiers in Immunology, 2017
Phage-display selection of immunoglobulin (IG) or antibody single chain Fragment variable (scFv) from combinatorial libraries is widely used for identifying new antibodies for novel targets.
Audrey Hemadou, Véronique Giudicelli, Melissa Laird Smith, Marie-Paule Lefranc, Patrice Duroux, Sofia Kossida, Cheryl Heiner, N. Lance Hepler, John Kuijpers, Alexis Groppi, Jonas Korlach, Philippe Mondon, Florence Ottones, Marie-Josée Jacobin-Valat, Jeanny Laroche-Traineau, Gisèle Clofent-Sanchez   +15 more
doaj   +1 more source

IMGT/V-QUEST: IMGT Standardized Analysis of the Immunoglobulin (IG) and T Cell Receptor (TR) Nucleotide Sequences

, 2011
INTRODUCTIONIMGT/V-QUEST is the integrated online IMGT tool for the standardized analysis of the immunoglobulin (IG) or antibody and T cell receptor (TR) rearranged nucleotide sequences.
Brochet, Xavier, Marie-Paule Lefranc, Xavier Brochet, Giudicelli, V., Lefranc, Mp, Giudicelli, Véronique, Véronique Giudicelli, Brochet, X., Lefranc, Marie-Paule   +8 more
core   +1 more source