Results 71 to 80 of about 8,734 (193)

Cold Agglutinin Disease–Like Genetic Signatures in Lymphoplasmacytic Lymphoma–Like Cases Challenge the WHO Fifth Edition Classification

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background The fifth edition of the World Health Organization (WHO) classification defines cold agglutinin disease (CAD) as a clonal B‐cell lymphoproliferative disorder occurring in the absence of overt lymphoma, whereas cases associated with lymphoma are classified as cold agglutinin syndrome (CAS).
Yuki Sato, Daisuke Koyama, Shoki Yamada, Kengo Suzuki, Masahiko Fukatsu, Yuka Oka, Yuko Hashimoto, Takayuki Ikezoe   +7 more
wiley   +1 more source

Standardized IMGT® Nomenclature of Salmonidae IGH Genes, the Paradigm of Atlantic Salmon and Rainbow Trout: From Genomics to Repertoires

Frontiers in Immunology, 2019
In teleost fish as in mammals, humoral adaptive immunity is based on B lymphocytes expressing highly diverse immunoglobulins (IG). During B cell differentiation, IG loci are subjected to genomic rearrangements of V, D, and J genes, producing a unique ...
Susana Magadan, Susana Magadan, Aleksei Krasnov, Saida Hadi-Saljoqi, Sergey Afanasyev, Stanislas Mondot, Delphine Lallias, Rosario Castro, Irene Salinas, Oriol Sunyer, John Hansen, Ben F. Koop, Marie-Paule Lefranc, Pierre Boudinot   +13 more
doaj   +1 more source

Structural analysis of Cu/Zn‐superoxide dismutase linked to neurodegenerative disease by antibody‐guided cryo‐EM

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Accumulation of misfolded proteins is a hallmark of many neurodegenerative diseases. To characterize such misfolded species in vivo, conformation‐specific antibodies are widely used; however, limited knowledge of antibody–epitope interactions often hampers mechanistic insight.
Yuki Shino, Norifumi Muraki, Yui Kobatake, Hiroaki Kamishina, Hirofumi Kosuge, Makoto Nakakido, Kouhei Tsumoto, Yoshiaki Furukawa   +7 more
wiley   +1 more source

Topology and expressed repertoire of the Felis catus T cell receptor loci

BMC Genomics, 2020
Background The domestic cat (Felis catus) is an important companion animal and is used as a large animal model for human disease. However, the comprehensive study of adaptive immunity in this species is hampered by the lack of data on lymphocyte antigen ...
Araya Radtanakatikanon, Stefan M. Keller, Nikos Darzentas, Peter F. Moore, Géraldine Folch, Viviane Nguefack Ngoune, Marie-Paule Lefranc, William Vernau   +7 more
doaj   +1 more source

Vascular Immune Remodeling: A CD4+ T Cell–Driven Immune Trajectory Associated With Arterial Stiffness

Aging Cell, Volume 25, Issue 6, June 2026.
This study integrated arterial stiffness with peripheral TCRβ repertoire and single‐cell transcriptomics in adults without cardiovascular disease, revealing a CD4+ T cell–driven “vascular immune remodeling” trajectory distinct from classical immunosenescence: increased TCR diversity, broad expansion of low‐frequency public clones and virus‐associated ...
Yu Miao, Bangwei Chen, Changqing Zeng, Xiaofen Wu, Minglei Yang, Cuntai Zhang, Jianguo Zhang, Yutao Du, Tao Li, Lei Ruan   +9 more
wiley   +1 more source

Standardized Sequence and Structure Analysis of Antibody Using IMGT®

, 2010
International audienceStandardized sequence and structure analysis of antibody using IMGT®, the international ImMunoGeneTics information system® (http://www.imgt.org), allows to bridge, for the first time, the gap between antibody sequences and three ...
Marie-Paule Lefranc, Duroux, Patrice, Ehrenmann, François, Patrice Duroux, François Ehrenmann, Giudicelli, Véronique, Véronique Giudicelli, Lefranc, Marie-Paule   +7 more
core   +1 more source

IMGT-Collier-de-Perles_light_chain.zip

, 2021
Supplementary information: 2D antibody structure information (Collier-de-Perles representation) of coronavirus related neutralizing antibodies. (for light chains)
Puneet Rawat (11551201)
core   +1 more source

Allele and haplotype frequencies of human leukocyte antigen-A, -B, -C, -DRB1, -DRB3/4/5, -DQA1, -DQB1, -DPA1, and -DPB1 by next generation sequencing-based typing in Koreans in South Korea.

PLoS ONE, 2021
Allele frequencies and haplotype frequencies of HLA-A, -B, -C, -DRB1, -DRB3/4/5, -DQA1, -DQB1, -DPA1, and -DPB1 have been rarely reported in South Koreans using unambiguous, phase-resolved next generation DNA sequencing.
In-Cheol Baek, Eun-Jeong Choi, Dong-Hwan Shin, Hyoung-Jae Kim, Haeyoun Choi, Tai-Gyu Kim   +5 more
doaj   +1 more source

Farmed Escapees Threaten MHC Diversity in Wild Atlantic Salmon

Evolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Wild Atlantic salmon populations in Norway and elsewhere are experiencing long‐term declines driven by reduced marine survival, climate change, impacts from aquaculture, introduction of alien species, and environmental degradation. Understanding how immune diversity is affected by these declines, and thus the ability of Atlantic salmon to ...
Morten Lukacs, Åse Helen Garseth, Sten Karlsson, Kyrre Kausrud, Ottavia Benedicenti, Arvind Y. M. Sundaram, Lars Austbø, Cathrine Arnason Bøe, Håvard Lo, Unni Grimholt   +9 more
wiley   +1 more source

From IMGT-ONTOLOGY IDENTIFICATION Axiom to IMGT Standardized Keywords: For Immunoglobulins (IG), T Cell Receptors (TR), and Conventional Genes

, 2011
INTRODUCTIONIMGT standardized keywords have been defined for the identification of immunoglobulins (IG) and T cell receptors (TR) and conventional genes.
Marie-Paule Lefranc, Lefranc, Mp
core   +1 more source