Results 91 to 100 of about 114,851,153 (292)

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

Advanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

Bioaccessibility and combined effect in transepithelial transport mechanisms of different dried thinned peach polyphenols

Food Chemistry: X
The present study evaluated the bioaccessibility and metabolic transport of different dried thinned peach polyphenols by using in vitro simulated digestion and Caco-2 cells models. Compared to freeze drying (FD) and natural drying (ND), hot air drying at
Chongting Guo, Xuan Li, Jiaxing Hu, Qingting Yu, Alberto Valdés, Alejandro Cifuentes, Jinfeng Bi   +6 more
doaj   +1 more source

In vitro gastrointestinal digestion of meat and fish with alcoholic beverages : oxidation and fatty acid ethyl ester formation

, 2022
Oxidative reactions during cooking and gastrointestinal digestion of meat and fish lead to the formation of various lipid-and protein oxidation products, some of which are toxic.
Vossen, ElsLA220020012653018020001242170000-0002-7212-3566F8AE6B8A-F0ED-11E1-A9DE-61C894A0A6B4, Van Pee, JasperLA220001809246028020039152970000-0002-6972-3552838A2A34-B157-11E8-8280-DC3D5707D3EF, Van Hecke, ThomasLA220020043380768020011910150000-0002-6176-652318091142-F0EE-11E1-A9DE-61C894A0A6B4, De Smet, StefaanLA228010009224660000-0003-1422-805XF4BDC958-F0ED-11E1-A9DE-61C894A0A6B4   +3 more
core  

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

Influence of the Encapsulating Agent on the Bioaccessibility of Phenolic Compounds from Microencapsulated Propolis Extract during In Vitro Gastrointestinal Digestion

Foods
The aim of this work is to develop different encapsulated propolis ingredients by spray-drying and to evaluate their bioaccessibility using simulated in vitro digestion.
Inés Cea-Pavez, David Manteca-Bautista, Alejandro Morillo-Gomar, Rosa Quirantes-Piné, José L. Quiles   +4 more
doaj   +1 more source

In Vitro Stability of Phytase from Recombinant Bacteria E. Coli BL21 (DE3) EAS1-AMP [PDF]

, 2011
The objective of the research was to inquire the Km, Vm, activity, intracellular phytase stability exposed to pH variation, temperature variation and protease (pepsin and pancreas) in vitro.
Nuhriawangsa, A. M. P., Wibowo, A., SAJIDAN,, Bachruddin, Z.   +3 more
core  

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Effect of Cooking Temperature on Protein Oxidation and in Vitro Digestive Properties of Yak Meat [PDF]

Shipin Kexue
The digestibility of myofibrillar proteins (MP) extracted from yak meat cooked to different internal temperatures of (40, 50, 60, 70 and 80 ℃) was determined during in vitro gastrointestinal digestion, and total carbonyl content, total sulfhydryl content
ZHANG Yan, LI Shengsheng, ZHAO Lizhu, ZHANG Qianglong
doaj   +1 more source

In vitro screening of probiotic lactic acid bacteria and prebiotic glucooligosaccharides to select effective synbiotics [PDF]

, 2010
Probiotics and prebiotics have been demonstrated to positively modulate the intestinal microflora and could promote host health. Although some studies have been performed on combinations of probiotics and prebiotics, constituting synbiotics, results on ...
Julien Grimoud, Durand, Henri, Henri Durand, Monsan, Pierre, Courtin, Céline, Grimoud, Julien, Theodorou, Vassilia, Christine Roques, Pierre Monsan, Françoise Ouarné, Ouarné, Françoise, Céline Courtin, Roques, Christine, Rogues, Christine, Vassilia Theodorou   +14 more
core   +1 more source