Results 81 to 90 of about 114,851,153 (292)

Antioxidant Activity and Mechanism of Simulated Digestion Products from Ready-to-Eat Sea Cucumber Body Wall Protein

open access: yesShipin gongye ke-ji
To explore the antioxidant activity of ready-to-eat sea cucumber—a mainstream commercial product—following digestion, this study first characterized the nutritional composition of ready-to-eat sea cucumber, and focused on analyzing the antioxidant ...
Long LI   +9 more
doaj   +1 more source

Starch Microstructure and Starch Hydrolysis in Barley and Oat Tempe During In Vitro Digestion.

open access: yes, 2012
Various botanical and structural characteristics of starchy foods are considered to modify the rate of starch digestion and the glycaemic responses in humans.
Kidman, Siv   +8 more
core   +1 more source

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun   +9 more
wiley   +1 more source

Effect of processing conditions and simulated gastrointestinal digestion on the activity of angiotensin I-converting enzyme (ACE) inhibitory peptide derived from duck meat hydrolysate

open access: yesCyTA - Journal of Food, 2019
In this study, the ACE-inhibitory peptide (
Caiyue Shi   +5 more
doaj   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

open access: yesAdvanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang   +9 more
wiley   +1 more source

Evaluation studies of persimmon plant (Diospyros kaki) for physiological benefits and bioaccessibility of antioxidants by in vitro simulated gastrointestinal digestion [PDF]

open access: yes, 2017
[EN] This study aims to analyze the antioxidant benefits from persimmon leaf tea, fruit and fibres taking into account their changes along gastrointestinal digestion. The evolution of polyphenols, flavonoids and antioxidant capacity was studied using the
Pinazo, A.   +3 more
core   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng   +7 more
wiley   +1 more source

Epigenetic Silencing of CYYR1 Promotes Lung Adenocarcinoma Progression Through TRIM21‐Dependent Regulation of HMMR Stability

open access: yesAdvanced Science, EarlyView.
CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai   +15 more
wiley   +1 more source

Stability and transepithelial transport of oligopeptide (KRQKYD) with hepatocyte-protective activity from Jinhua ham in human intestinal Caco-2 monolayer cells

open access: yesFood Science and Human Wellness
The study evaluated the stability of an oligopeptide (Lys-Arg-Gln-Lys-Tyr-Asp, KRQKYD) and its transport mechanism by simulating gastrointestinal digestion and a model of human intestinal Caco-2 monolayer cells in vitro.
Wen Nie   +5 more
doaj   +1 more source

A multi-center peptidomic investigation of simulated gastrointestinal food digestion

open access: yes, 2022
Background: Mass spectrometry has become the techniques of choice for the simultaneous assessment of a high variety of molecules in complex matrices. For this reason, it is best suited for precisely monitoring the evolution of digestive processes in vivo
P. Jimenez Barrios   +21 more
core  

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