Results 21 to 30 of about 167,569,374 (255)

A Dynamic Stochastic Model for DNA Replication Initiation in Early Embryos [PDF]

, 2008
Background: Eukaryotic cells seem unable to monitor replication completion during normal S phase, yet must ensure a reliable replication completion time.
Labit, H, Goldar, A, Marheineke, K, Olivier Hyrien, Hélène Labit, Hyrien, O, Kathrin Marheineke, Arach Goldar   +7 more
core   +2 more sources

Structure and Function of the Campylobacter jejuni Chromosome Replication Origin

Frontiers in Microbiology, 2018
Campylobacter jejuni is the leading bacterial cause of foodborne infections worldwide. However, our understanding of its cell cycle is poor. We identified the probable C.
Pawel Jaworski, Rafal Donczew, Thorsten Mielke, Christoph Weigel, Kerstin Stingl, Anna Zawilak-Pawlik   +5 more
doaj   +1 more source

Escherichia coli cell factories with altered chromosomal replication scenarios exhibit accelerated growth and rapid biomass production

Microbial Cell Factories, 2022
Background Generally, bacteria have a circular genome with a single replication origin for each replicon, whereas archaea and eukaryotes can have multiple replication origins in a single chromosome.
Hee Jin Yang, Kitae Kim, Soon-Kyeong Kwon, Jihyun F. Kim   +3 more
doaj   +1 more source

High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination [PDF]

, 2013
Copyright © 2013 The Authors. Published by Elsevier Inc.
Nieduszynski, Conrad A, Tanaka, Tomoyuki U.; id_orcid, de Moura, Alessandro P. S., Tanaka, Tomoyuki U., Saner, Nazan, de Moura, Alessandro P S, Nieduszynski, Conrad A., deMoura, Alessandro P. S., Hawkins, Michelle, Renata Retkute, Müller, Carolin A, Tanaka, Tomoyuki U, Alessandro P.S. de Moura, Tomoyuki U. Tanaka, Michelle Hawkins, M�ller, Carolin A., Müller, Carolin A., de Moura, Alessandro P.S., Carolin A. Müller, Nazan Saner, Retkute, Renata, Conrad A. Nieduszynski   +21 more
core   +1 more source

Chromosomal macrodomains and associated proteins : implications for DNA organization and replication in gram negative bacteria [PDF]

, 2011
The Escherichia coli chromosome is organized into four macrodomains, the function and organisation of which are poorly understood. In this review we focus on the MatP, SeqA, and SlmA proteins that have recently been identified as the first examples of ...
Kalmykowa, Olga J., Remus T. Dame, Kalmykowa, OJ, Dame Remus T., Grainger David C., Dame, Remus T. (Remus Thei), David C Grainger, Grainger, David, Kalmykowa Olga J., David C. Grainger, Dame, RT, Olga J Kalmykowa, Grainger, David C., Remus T Dame, Olga J. Kalmykowa   +14 more
core   +1 more source

Functional centromeres determine the activation time of pericentric origins of DNA replication in Saccharomyces cerevisiae. [PDF]

PLoS Genetics, 2012
The centromeric regions of all Saccharomyces cerevisiae chromosomes are found in early replicating domains, a property conserved among centromeres in fungi and some higher eukaryotes. Surprisingly, little is known about the biological significance or the
Thomas J Pohl, Bonita J Brewer, M K Raghuraman   +2 more
doaj   +1 more source

Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels [PDF]

, 2010
In the metazoan replication timing program, clusters of replication origins located in different subchromosomal domains fire at different times during S phase. We have used Xenopus laevis egg extracts to drive an accelerated replication timing program in
Blow, J. Julian; id_orcid, Thomson, Alexander M., Gillespie, Peter J., Peter J. Gillespie, J. Julian Blow, Blow, J. Julian, Alexander M. Thomson   +6 more
core   +1 more source

Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective

Frontiers in Microbiology, 2018
Bacterial chromosomes have a single, unique replication origin (named oriC), from which DNA synthesis starts. This study describes methods of visualizing oriC regions and the chromosome replication in single living bacterial cells in real-time.
Damian Trojanowski, Joanna Hołówka, Jolanta Zakrzewska-Czerwińska   +2 more
doaj   +1 more source

Prokaryotic ParA–ParB–parS system links bacterial chromosome segregation with the cell cycle [PDF]

, 2012
While the essential role of episomal par loci in plasmid DNA partitioning has long been appreciated, the function of chromosomally encoded par loci is less clear. The chromosomal parA–parB genes are conserved throughout the bacterial kingdom and encode
Mierzejewska, Jolanta, Jolanta Mierzejewska, Grażyna Jagura-Burdzy, Jagura-Burdzy, Grazyna   +3 more
core   +1 more source

Genetic and physical mapping of DNA replication origins in Haloferax volcanii. [PDF]

PLoS Genetics, 2007
The halophilic archaeon Haloferax volcanii has a multireplicon genome, consisting of a main chromosome, three secondary chromosomes, and a plasmid. Genes for the initiator protein Cdc6/Orc1, which are commonly located adjacent to archaeal origins of DNA ...
Cédric Norais, Michelle Hawkins, Amber L Hartman, Jonathan A Eisen, Hannu Myllykallio, Thorsten Allers   +5 more
doaj   +1 more source