Results 1 to 10 of about 203,114 (264)
Frontiers in Plant Science, 2023 Cellular homeostasis of the micronutrient iron is highly regulated in plants and responsive to nutrition, stress, and developmental signals. Genes for iron management encode metal and other transporters, enzymes synthesizing chelators and reducing ...
Hans-Jörg Mai +3 more
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Minireview: Chromatin-based regulation of iron homeostasis in plants
Frontiers in Plant Science, 2022 Plants utilize delicate mechanisms to effectively respond to changes in the availability of nutrients such as iron. The responses to iron status involve controlling gene expression at multiple levels.
Justin Su +4 more
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Non-invasive assessment of normal and impaired iron homeostasis in the brain
Nature Communications, 2023 Strict iron regulation is essential for normal brain function. The iron homeostasis, determined by the milieu of available iron compounds, is impaired in aging, neurodegenerative diseases and cancer.
Shir Filo +9 more
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Advanced Science, 2023 Doxorubicin (DOX)‐induced cardiotoxicity (DoIC) is a major side effect for cancer patients. Recently, ferroptosis, triggered by iron overload, is demonstrated to play a role in DoIC.
Jianan Pan +11 more
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Interpreting Iron Homeostasis in Congenital and Acquired Disorders
Pharmaceuticals, 2023 Mammalian cells require iron to satisfy their metabolic needs and to accomplish specialized functions, such as hematopoiesis, mitochondrial biogenesis, energy metabolism, or oxygen transport.
Natalia Scaramellini +5 more
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Host and microbiota derived extracellular vesicles: Crucial players in iron homeostasis
Frontiers in Medicine, 2022 Iron is a double-edged sword. It is vital for all that’s living, yet its deficiency or overload can be fatal. In humans, iron homeostasis is tightly regulated at both cellular and systemic levels.
Yasmeen Daou +8 more
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Brain Iron Homeostasis and Mental Disorders
Antioxidants, 2023 Iron plays an essential role in various physiological processes. A disruption in iron homeostasis can lead to severe consequences, including impaired neurodevelopment, neurodegenerative disorders, stroke, and cancer.
Qiong Wu +4 more
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Antioxidants, 2021 Iron accumulation and neuroinflammation are pathological conditions found in several neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Iron and inflammation are intertwined in a bidirectional relationship, where
Pamela J. Urrutia +2 more
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Microbiology Spectrum, 2023 Zinc excess is toxic to bacteria and, thus, represents an important innate defense mechanism of host cells, especially against mycobacterial infections.
Xiaohui Li +4 more
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The Role of Sulfur in Agronomic Biofortification with Essential Micronutrients
Plants, 2022 Sulfur (S) is an essential macronutrient for plants, being necessary for their growth and metabolism and exhibiting diverse roles throughout their life cycles. Inside the plant body, S is present either in one of its inorganic forms or incorporated in an
Styliani N. Chorianopoulou +1 more
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