Results 41 to 50 of about 1,098,743 (202)
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Iron homeostasis imbalance and ferroptosis in brain diseases
MedComm, 2023 Brain iron homeostasis is maintained through the normal function of blood–brain barrier and iron regulation at the systemic and cellular levels, which is fundamental to normal brain function.
Haining Long +3 more
doaj +1 more source
The effect of iron on hepatitis C virus replication [PDF]
, 2011 Hepatitis C virus (HCV) is a small RNA encoded virus that causes acute and chronic infections of the liver and is associated with fibrosis, cirrhosis, hepatocellular carcinoma and end-stage liver disease.
Clark, Hayley
core
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Applied and Environmental MicrobiologyIron is a vital cofactor for enzymes essential to many biological processes, yet in excess, it poses a danger to all living organisms. In order to ensure survival and proliferation under fluctuating environmental iron levels, bacteria evolve ...
Kaiyue Jie +5 more
doaj +1 more source
Iron Homeostasis in Azotobacter vinelandii
Biology, 2023 Iron is an essential nutrient for all life forms. Specialized mechanisms exist in bacteria to ensure iron uptake and its delivery to key enzymes within the cell, while preventing toxicity.
Elena Rosa-Núñez +6 more
doaj +1 more source
Indices of iron homeostasis correlate with airway obstruction in an NHANES III cohort
, 2017 Andrew J Ghio, Elizabeth D Hilborn Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, Chapel Hill, NC, USA Abstract: Cigarette smoking results in the accumulation of iron both systemically and locally ...
Hilborn ED +3 more
core +1 more source
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source
Biomedical Papers, 2016 Background and Aims: Erythropoiesis is closely related to iron metabolism in a balanced homeostasis. Analyses of diverse erythroid and iron metabolism disorders have shown that disrupted erythropoiesis negatively affects iron homeostasis and vice versa ...
Lucie Sulovska +8 more
doaj +1 more source