Results 41 to 50 of about 1,598,338 (286)
Iron homeostasis in the Metabolic Syndrome [PDF]
European Journal of Clinical Investigation, 2013 AbstractThe metabolic syndrome (MetS) affects iron homeostasis in a many‐faceted fashion. On the one side, hyperferritinaemia with normal or mildly elevated transferrin saturation is observed in approximately one‐third of patients with non‐alcoholic fatty liver disease (NAFLD) or the MetS.
Christian, Datz +3 more
openaire +2 more sources
Collection Series "Iron Homeostasis". [PDF]
Int J Mol SciIron is essential for almost all living organisms, but excess or deregulated iron is potentially toxic [...]
Roetto A, Arosio P.
europepmc +4 more sources
Frontiers in Cell and Developmental Biology, 2021 Objective: Iron overload is common in elderly people which is associated with an increased prevalence of osteoarthritis (OA), but the exact role of iron in the development of OA has not been established.
Xingzhi Jing +9 more
doaj +1 more source
Current understanding of iron homeostasis [PDF]
The American Journal of Clinical Nutrition, 2017 Iron is an essential trace element, but it is also toxic in excess, and thus mammals have developed elegant mechanisms for keeping both cellular and whole-body iron concentrations within the optimal physiologic range. In the diet, iron is either sequestered within heme or in various nonheme forms.
Anderson, Gregory J., Frazer, David M.
openaire +4 more sources
G3: Genes, Genomes, Genetics, 2021 Monothiol glutaredoxins are important regulators of iron homeostasis that play conserved roles in the sensing and trafficking of iron-sulfur clusters.
Guanggan Hu +5 more
doaj +1 more source
Dysregulation of iron homeostasis in airways associated with persistent preschool wheezing
Respiratory Research, 2023 Background Currently, there are no reliable clinical tools available to identify persistent asthma symptoms among preschool children with recurrent wheezing.
Zhili Wang +5 more
doaj +1 more source
Haptoglobin Polymorphism and Iron Homeostasis [PDF]
Clinical Chemistry, 2002 Abstract Background: There is a marked difference in the degree of expression of the homozygous C282Y HFE genotype that is associated with hereditary hemochromatosis. It has been reported that individuals with the haptoglobin 2-2 type manifest increased iron concentrations, including serum iron, transferrin saturation, and ferritin.
Ernest, Beutler +2 more
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FIT-Binding Proteins and Their Functions in the Regulation of Fe Homeostasis
Frontiers in Plant Science, 2019 Iron, as an essential micronutrient, is required by all living organisms. In plants, the deficiency and excess of iron will impair their growth and development.
Huilan Wu +2 more
doaj +1 more source
Nitric oxide and glutathione impact the expression of iron uptake- and iron transport-related genes as well as the content of metals in A. thaliana plants grown under iron deficiency [PDF]
, 2012 Mounting evidence indicate that nitric oxide (NO) acts as a signaling molecule mediating iron deficiency responses through the up-regulation of the expression of iron uptake-related genes.
Dobrowolska, Grażyna, Szymańska, K
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