Results 11 to 20 of about 1,598,338 (286)
Mitoferrin, Cellular and Mitochondrial Iron Homeostasis
Cells, 2022 Iron is essential for many cellular processes, but cellular iron homeostasis must be maintained to ensure the balance of cellular signaling processes and prevent disease.
Md Yousuf Ali +3 more
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Iron Homeostasis and the Inflammatory Response [PDF]
Annual Review of Nutrition, 2010 Iron and its homeostasis are intimately tied to the inflammatory response. The adaptation to iron deficiency, which confers resistance to infection and improves the inflammatory condition, underlies what is probably the most obvious link: the anemia of inflammation or chronic disease.
Marianne Wessling-Resnick
openaire +3 more sources
Iron homeostasis: An anthropocentric perspective [PDF]
Journal of Biological Chemistry, 2017 The regulation of iron metabolism in biological systems centers on providing adequate iron for cellular function while limiting iron toxicity. Because mammals cannot excrete iron, mechanisms have evolved to control iron acquisition, storage, and distribution at both systemic and cellular levels.
Coffey, Richard, Ganz, Tomas
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Heme Oxygenase Activity Correlates with Serum Indices of Iron Homeostasis in Healthy Nonsmokers
Biomarker Insights, 2016 Heme oxygenase (HO) catalyzes the breakdown of heme to carbon monoxide, iron, and biliverdin. While the use of genetically altered animal models in investigation has established distinct associations between HO activity and systemic iron availability ...
Andrew J. Ghio, Dina M. Schreinemachers
doaj +2 more sources
Mitochondrial Iron Transport and Homeostasis in Plants [PDF]
Frontiers in Plant Science, 2013 Iron (Fe) is an essential nutrient for plants and although the mechanisms controlling iron uptake from the soil are relatively well understood, comparatively little is known about subcellular trafficking of iron in plant cells.
Anshika eJain, Erin L Connolly
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ABOUT THE OPPORTUNITIES TO Influence MICROORGANISMS ON THE IRON HOMEOSTASIS IN THE HOST ORGANISM (Literature review) [PDF]
Acta Biomedica Scientifica, 2014 Iron homeostasis, aimed at depriving the pathogen of available iron, takes an important role in protecting human body against pathogens. When infection occurs, microorganisms must overcome iron deficiency in a host organism.
V. V. Leonov +3 more
doaj +1 more source
Interpreting Iron Homeostasis in Congenital and Acquired Disorders
Pharmaceuticals, 2023 Mammalian cells require iron to satisfy their metabolic needs and to accomplish specialized functions, such as hematopoiesis, mitochondrial biogenesis, energy metabolism, or oxygen transport.
Natalia Scaramellini +5 more
doaj +1 more source
Advanced Science, 2023 Doxorubicin (DOX)‐induced cardiotoxicity (DoIC) is a major side effect for cancer patients. Recently, ferroptosis, triggered by iron overload, is demonstrated to play a role in DoIC.
Jianan Pan +11 more
doaj +1 more source
Bacterial iron homeostasis [PDF]
FEMS Microbiology Reviews, 2003 Iron is essential to virtually all organisms, but poses problems of toxicity and poor solubility. Bacteria have evolved various mechanisms to counter the problems imposed by their iron dependence, allowing them to achieve effective iron homeostasis under a range of iron regimes.
Simon C, Andrews +2 more
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Host and microbiota derived extracellular vesicles: Crucial players in iron homeostasis
Frontiers in Medicine, 2022 Iron is a double-edged sword. It is vital for all that’s living, yet its deficiency or overload can be fatal. In humans, iron homeostasis is tightly regulated at both cellular and systemic levels.
Yasmeen Daou +8 more
doaj +1 more source