Results 11 to 20 of about 1,098,743 (202)

Iron Uptake and Homeostasis in Microorganisms

open access: yes, 2010
Preface. Iron is considered to be a minor element employed, in a variety of forms, by nearly all living organisms. In some cases, it is utilised in large quantities, for instance for the formation of magnetosomes within magnetotactic bacteria or ...

core   +9 more sources

Analysis of MRI-derived spleen iron in the UK Biobank identifies genetic variation linked to iron homeostasis and hemolysis [PDF]

open access: yes, 2022
The spleen plays a key role in iron homeostasis. It is the largest filter of the blood and performs iron reuptake from old or damaged erythrocytes. Despite this role, spleen iron concentration has not been measured in a large, population-based cohort. In
Sorokin, E.   +7 more
core   +1 more source

Inflaming the Brain with Iron

open access: yesAntioxidants, 2021
Iron accumulation and neuroinflammation are pathological conditions found in several neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Iron and inflammation are intertwined in a bidirectional relationship, where
Pamela J. Urrutia   +2 more
doaj   +1 more source

Zinc excess impairs Mycobacterium bovis growth through triggering a Zur-IdeR-iron homeostasis signal pathway

open access: yesMicrobiology Spectrum, 2023
Zinc excess is toxic to bacteria and, thus, represents an important innate defense mechanism of host cells, especially against mycobacterial infections.
Xiaohui Li   +4 more
doaj   +1 more source

The Role of Sulfur in Agronomic Biofortification with Essential Micronutrients

open access: yesPlants, 2022
Sulfur (S) is an essential macronutrient for plants, being necessary for their growth and metabolism and exhibiting diverse roles throughout their life cycles. Inside the plant body, S is present either in one of its inorganic forms or incorporated in an
Styliani N. Chorianopoulou   +1 more
doaj   +1 more source

The monothiol glutaredoxin Grx4 influences thermotolerance, cell wall integrity, and Mpk1 signaling in Cryptococcus neoformans

open access: yesG3: Genes, Genomes, Genetics, 2021
Monothiol glutaredoxins are important regulators of iron homeostasis that play conserved roles in the sensing and trafficking of iron-sulfur clusters.
Guanggan Hu   +5 more
doaj   +1 more source

Insights into molecular mechanisms of disease in Neurodegeneration with Brain Iron Accumulation; unifying theories. [PDF]

open access: yes, 2016
Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterised by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated ...
Arber, C   +7 more
core   +1 more source

Metalloreductase Steap3 coordinates the regulation of iron homeostasis and inflammatory responses

open access: yesHaematologica, 2012
Background Iron and its homeostasis are intimately related to inflammatory responses, but the underlying molecular mechanisms are poorly understood. We investigated the role of Steap3 in regulating iron homeostasis in macrophages, and the effects of ...
Fan Zhang   +8 more
doaj   +1 more source

Benefits and risks of iron supplementation in anemic neonatal pigs. [PDF]

open access: yes, 2010
Iron deficiency is a common health problem. The most severe consequence of this disorder is iron deficiency anemia (IDA), which is considered the most common nutritional deficiency worldwide. Newborn piglets are an ideal model to explore the multifaceted
Thibaudeau, Olivier   +12 more
core   +2 more sources

Mitoferrin, Cellular and Mitochondrial Iron Homeostasis

open access: yesCells, 2022
Iron is essential for many cellular processes, but cellular iron homeostasis must be maintained to ensure the balance of cellular signaling processes and prevent disease.
Md Yousuf Ali   +3 more
doaj   +1 more source

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