Results 11 to 20 of about 315,195 (302)
Down the Iron Path: Mitochondrial Iron Homeostasis and Beyond
Cells, 2021 Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent. Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate these cofactors along with iron ions into mitochondrial proteins that support ...
Jonathan Dietz +2 more
exaly +3 more sources
Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]
International Journal of Molecular Sciences, 2017 Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo +4 more
core +7 more sources
The critical role of iron homeostasis in neurodegenerative diseases. [PDF]
Neural Regen ResNeurodegenerative diseases are prevalent conditions that greatly impact human health. These diseases are primarily characterized by the progressive loss and eventual death of neuronal function, although the precise mechanisms underlying these processes ...
Liang T +9 more
europepmc +2 more sources
Iron Homeostasis in the Lungs—A Balance between Health and Disease
Pharmaceuticals, 2019 A strong mechanistic link between the regulation of iron homeostasis and oxygen sensing is evident in the lung, where both systems must be properly controlled to maintain lung function.
Max Gassmann, Martina U Muckenthaler
exaly +3 more sources
Abnormal Iron Homeostasis and Neurodegeneration [PDF]
Frontiers in Aging Neuroscience, 2013 Abnormal iron metabolism is observed in many neurodegenerative diseases, however only two have shown dysregulation of brain iron homeostasis as the primary cause of neurodegeneration.
Barry B Muhoberac, Ruben eVidal
doaj +3 more sources
Iron Homeostasis in Azotobacter vinelandii
Biology, 2023 Iron is an essential nutrient for all life forms. Specialized mechanisms exist in bacteria to ensure iron uptake and its delivery to key enzymes within the cell, while preventing toxicity.
Elena Rosa-Núñez +6 more
doaj +4 more sources
Iron homeostasis in the lung [PDF]
Biological Research, 2006 Iron is essential for many aspects of cellular function. However, it also can generate oxygen-based free radicals that result in injury to biological molecules. For this reason, iron acquisition and distribution are tightly regulated.
ANDREW J GHIO +4 more
doaj +4 more sources
Frontiers in Plant Science, 2023 Cellular homeostasis of the micronutrient iron is highly regulated in plants and responsive to nutrition, stress, and developmental signals. Genes for iron management encode metal and other transporters, enzymes synthesizing chelators and reducing ...
Hans-Jörg Mai +3 more
doaj +1 more source
Minireview: Chromatin-based regulation of iron homeostasis in plants
Frontiers in Plant Science, 2022 Plants utilize delicate mechanisms to effectively respond to changes in the availability of nutrients such as iron. The responses to iron status involve controlling gene expression at multiple levels.
Justin Su +4 more
doaj +1 more source
Bacterial iron homeostasis [PDF]
FEMS Microbiology Reviews, 2003 Iron is essential to virtually all organisms, but poses problems of toxicity and poor solubility. Bacteria have evolved various mechanisms to counter the problems imposed by their iron dependence, allowing them to achieve effective iron homeostasis under a range of iron regimes.
Simon C, Andrews +2 more
openaire +2 more sources