Results 121 to 130 of about 41,015 (259)
THE TRANSAMINATION OF KYNURENINE
Journal of Biological Chemistry, 1953 I L, MILLER, M, TSUCHIDA, E A, ADELBERG
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British Journal of Pharmacology, EarlyView.As a metabolically versatile organ, the heart is capable of generating energy from a wide range of substrates. Although fatty acid and glucose metabolism in the heart have been extensively studied, the contribution of amino acid metabolism to cardiac physiology and disease is gaining increasing attention.
Tayyiba Azam +6 more
wiley +1 more source
Cancer Science, EarlyView.Through comprehensive analysis of plasma and urine from patients with esophageal cancer and healthy controls, 3‐indoxyl sulfate and O‐acetylcarnitine were identified as metabolites significantly associated with esophageal cancer. These metabolites were elevated in patients and demonstrated promising diagnostic performance for early detection.
Kenji Hamada +8 more
wiley +1 more source
Urinary kynurenine,tryptophan, and neopterin concentrations during physiological pregnancy
Scientific ReportsDuring pregnancy the alterations of kynurenine and tryptophan metabolism play an important role in local signalling and the prevention of fetal rejection.
Lenka Kujovská Krčmová +9 more
doaj +1 more source
CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems
The FEBS Journal, EarlyView.Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén +11 more
wiley +1 more source
Some Effects of Steroid Hormones and Kynurenine on Tryptophan and its Conversion to 5-Hydroxytryptamine [PDF]
The relationship of certain steroid hormones to mood state in humans and to biochemical parameters related to 5-hydroxytryptamine function in the brains of mice have been studied.
Gould, Susan E.
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Hepatology Research, EarlyView.IDO‐1 immunostaining identifies primary biliary cholangitis even in morphologically subtle bile duct lesions. IDO‐1 expression reflects cholangitis activity and is suppressed by ursodeoxycholic acid treatment, indicating its value as a dynamic diagnostic adjunct rather than a static marker of chronic damage.
Kaori Yoshimura +10 more
wiley +1 more source
Simplified schematic of the kynurenine pathway (KP).
, 2013 IDO-1, indoleamine dioxygenase; TDO, tryptophan dioxygenase; AFMID, arylformamidase; KAT 1–3, kynurenine amino transferase 1, 2 and 3; KMO, kynurenine 3-hydroxylase; KYNU, kynureninase; 3HAAO, 3-hydroxyanthranilic acid oxidase; ACMSD, amino ...
Chai K. Lim (404939) +9 more
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Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases
Journal of Periodontal Research, EarlyView.This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi +10 more
wiley +1 more source
Objectives The importance of the kynurenine pathway in normal immune system function has led to an appreciation of its possible contribution to autoimmune disorders such as rheumatoid arthritis (RA).
Dorota Sikorska +5 more
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