Results 101 to 110 of about 6,762 (168)

NSUN2/YBX1 promotes the progression of breast cancer by enhancing HGH1 mRNA stability through m5C methylation

Breast Cancer Research
Background RNA m5C methylation has been extensively implicated in the occurrence and development of tumors. As the main methyltransferase, NSUN2 plays a crucial regulatory role across diverse tumor types. However, the precise impact of NSUN2-mediated m5C
Xuran Zhang, Ke An, Xin Ge, Yuanyuan Sun, Jingyao Wei, Weihong Ren, Han Wang, Yueqin Wang, Yue Du, Lulu He, Ouwen Li, Shaoxuan Zhou, Yong Shi, Tong Ren, Yun-gui Yang, Quancheng Kan, Xin Tian   +16 more
doaj   +1 more source

Transcriptome-wide RNA 5-methylcytosine profiles of human iPSCs and iPSC-derived cardiomyocytes

Scientific Data
Cardiac regenerative therapy has recently progressed by reprogramming somatic cells into induced pluripotent stem cells (iPSCs) and advanced by large-scale differentiation-derived cardiomyocytes (hiPSC-CMs).
Szu-Ying Chen, Yi-Hsien Fang, Chen-Yu Huang, Jou-Hsien Wu, Yan-Shen Shan, Yen-Wen Liu, Po-Hsien Huang   +6 more
doaj   +1 more source

Emerging roles of RNA N5-methylcytosine modification in reproductive physiology and gynecological diseases. [PDF]

Epigenetics
Lv F, Jin Y, Yu S, Yang X, Xia S, Ye X, Zhao Q, Hu Y, Zheng A, Wu Y, Tong J.   +10 more
europepmc   +1 more source

m5C: Novel Diagnostic and Drug Repurposing Targets for Nonalcoholic Steatohepatitis. [PDF]

Int J Genomics
Chen S, Duan R, Qiu J, Lei Z, Chen W, Li X.   +5 more
europepmc   +1 more source

Enhancing plant antiviral responses and productivity through the elimination of m⁵C methyltransferase. [PDF]

Sci Adv
Jiang Y, Liu P, Zhang M, Yong B, Yin J, Chen L, Shi C, Li P, Guo Y, Hu H, Feng L, Chen L, Zhang T, Liu J, Zhong K, Zhou X, Chen F, Chen J, Yang J.   +18 more
europepmc   +1 more source

Deep learning model and omics screening highlight angiotensinogen as a 5-methylcytosine (m⁵C) regulated mediator of tumor-microenvironment communication in liver cancer. [PDF]

Front Immunol
Pang H, Wang L, Li Y, Zhou Y.
europepmc   +1 more source

Epitranscriptomic profiling of m5C RNA methylation reveals a dynamic response to TSWV infection in tomato. [PDF]

Front Plant Sci
Zhao X, Gong Y, Jiao Y, Zhang W, An D, Wang Y, Lv B, Li Y, Shen L, Yang J.   +9 more
europepmc   +1 more source

DNMT2 inhibits anaplastic thyroid cancer progression by downregulating 5'tiRNA^Gly-GCC production. [PDF]

Cell Death Dis
Zhou R, Li B, Cao M, Wu Z, Xia F, Li X.
europepmc   +1 more source

Global discovery of RNA modifications and functional analysis of m⁵C methylome in cyanobacteria. [PDF]

J Biol Chem
Cao G, Ling M, Zhan J, Lin J, Yuan L, Yang M, Ge F.   +6 more
europepmc   +1 more source

NSUN5 and RNA m⁵C epitranscriptomic regulation in tumor progression. [PDF]

Front Cell Dev Biol
Zhou Q, Li C, Jiang X, Yuan Y, Zhou Q, Wang Q, Jiang L.   +6 more
europepmc   +1 more source