Results 111 to 120 of about 171,203 (189)

DNA methylation in follicular lymphoma [PDF]

, 2010
PhDFollicular Lymphoma (FL) is a common B cell Non-Hodgkin Lymphoma with a median survival of 8-10 years. Patients frequently undergo transformation to a more aggressive lymphoma and this is associated with drastically reduced survival.
Ó Riain, Ciarán Liam
core  

Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF) after acute psychosocial stress [PDF]

, 2012
Environmentally induced epigenetic alterations are related to mental health. We investigated quantitative DNA methylation status before and after an acute psychosocial stressor in two stress-related genes: oxytocin receptor (OXTR) and brain-derived ...
Dempster, E., Dempster, Emma, Unternaehrer, Eva, Lieb, Roselind, Meyer, A. H., Unternaehrer, E., Luers, P., Mill, J., Staehli, S., Hellhammer, D. H., Meyer, Andrea H., Lieb, R., Meinlschmidt, G., Staehli, Simon, Mill, John, Hellhammer, Dirk H., Meinlschmidt, Gunther, Luers P, Meinlschmidt G, Lieb R, Meyer AH, Dempster E, Staehli S, Hellhammer DH, Mill J, Unternaehrer E   +25 more
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NSUN2-mediated RNA m5C modification drives multiple myeloma progression by enhancing the stability of HIP1 mRNA

Scientific Reports
RNA 5-methylcytosine (m5C) modification is a crucial epigenetic regulation, and aberrant m5C methylation is associated with the pathogenesis of certain cancers.
Yang Jiang, Jing Sun, Yuyan Chen, Lin Cheng, Saran Feng, Yan Wang, Congcong Sun   +6 more
doaj   +1 more source

NSUN2-Mediated M5c Dysregulation Promotes OSCC Ferroptosis

International Dental Journal
Aim or purpose: This study aimed to investigate the role of NSUN2-mediated 5-methylcytosine (m5C) methylation in regulating ferroptosis resistance and tumor progression in oral squamous cell carcinoma (OSCC), identifying potential epitranscriptomic ...
Yunyang Lu, Wei Zhao, Fangyang Shi, Jie Wu, Hui Gao, Hui Zhang, Jiajun Hu, Shiyu Lv, Weidong Du, Runze Li   +9 more
doaj   +1 more source

Variability of DNA methylation pattern in somatic and germ cells in male newt (Amphibia, Urodela) Triturus cristatus carnifex

, 1998
In a survey of several mammalian genomes, namely humans, rodents and bovines, the differences in the 5-methylcytosine (m5C) content show that repeated DNA sequences from sperm were undermethylated and from various somatic tissues were heavily methylated.
Giovanni Pontecorvo, Pontecorvo G, Bruna De Felice, Carfagna M., Mario Carfagna, DE FELICE, Bruna   +5 more
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DNA methylation patterns in cord blood DNA and body size in childhood. [PDF]

, 2012
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.BACKGROUND ...
Pearce, M., Mark S. Pearce (177539), Ness, Andy R, Caroline L Relton, St Pourcain, B., Joseph Trakalo (177545), Shaheen Seif O., Embleton, N., Swan, DC, Ness, AR, George Davey Smith (82619), Seif O. Shaheen (177559), Shaheen, S., Relton, Caroline L, Ring, SM, Relton, C., Jon H Tobias, Swan, D., Sayers, AE, Alexandra Groom, Caroline L. Relton (174120), Susan M. Ring (116089), Embleton Nicholas D., Alexandra Groom (174101), Andy R Ness, Andy R. Ness (177551), Ring Susan M., Beate St. Pourcain (152905), Sayers, Adrian E, Tobias Jon H., Ness Andy R., Trakalo, J, St Pourcain, B, Sayers Adrian E., Groom, A., Tobias, Jonathan H, Relton Caroline L., St. Pourcain Beate, St Pourcain, M U B, Nicholas D Embleton, Tobias, J., Jon H. Tobias (153172), Northstone, K., Beate St Pourcain, Northstone, K, Davey Smith George, Trakalo Joseph, Groom Alexandra, Joseph Trakalo, Sayers, A., Kate Northstone (74777), Tobias, JH, Davey Smith, George, Groom, A, Ring, Susan M, Davey Smith, G, Pearce, MS, Northstone, Kate, Nicholas D. Embleton (177535), Susan M Ring, Pearce Mark S., Daniel C Swan, Ness, A., Swan Daniel C., Mark S Pearce, Northstone Kate, Relton, CL, Adrian E Sayers, Shaheen, SO, George Davey Smith, Trakalo, J., Adrian E. Sayers (177532), Embleton, ND, Davey Smith, G., Kate Northstone, Seif O Shaheen, Ring, S., Daniel C. Swan (124594)   +77 more
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Association between DNA methylation of HSPB1 and death in low Gleason score prostate cancer. [PDF]

, 2012
BACKGROUND: Heat shock protein 27 (Hsp-27) encoded by gene HSPB1 is a critical regulator of the behavioral phenotype of human prostate cancer (PCa) cells, enhanced expression being associated with highly aggressive disease and poor clinical outcome.
M A Thorat, Beesley, C, Lorincz, AT, Y-J Lu, H Møller, Y Yu, Cuzick, J, D M Berney, Moller, Henrik; id_orcid, N Vasiljević, Ahmad, A S, C Beesley, Moller, H, J Cuzick, Lu, Y-J, Berney, DM, Foster, C S, Thorat, M A, Vasiljević, N, Ahmad, AS, Fisher, G, Møller, H, Foster, CS, A T Lorincz, Yu, Y, G Fisher, C S Foster, A S Ahmad, Lorincz, A T, Thorat, MA, Berney, D M   +30 more
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NSUN2-mediated m5C hypermethylation of hsa_circ_0004516 promotes breast cancer brain metastasis by activating AKT signaling

Non-coding RNA Research
Breast cancer brain metastasis (BCBM) remains fatal with elusive mechanisms. Here, we unveil the first circRNA m5C methylation landscape in BCBM through MeRIP-seq (methylated RNA immunoprecipitation next-generation sequencing) identifying 7465 BCBM ...
Min Li, Jiawei Li, Hongbo Wen, Jun Li, Song Wang, Jianran Guo, Dongyan Zhang, Anqi Zhang, Chuanyou Cui, Rong Fu, Meng An, Wei Zhang, Bo Fu   +12 more
doaj   +1 more source

Analysis of tissue-specific & allele-specific DNA methylation [PDF]

, 2010
Epigenetic mechanisms such as histone modifications and DNA methylation extend the information of the underlying genomic DNA sequence. Understanding cell type-specific epigenetic codes on a global level is a major challenge after the sequencing of the ...
Schilling, Elmar
core   +1 more source

Deciphering the Divergent Gene Expression Landscapes of m6A/m5C/m1A Methylation Regulators in Hepatocellular Carcinoma Through Single-Cell and Bulk RNA Transcriptomic Analysis

Journal of Hepatocellular Carcinoma, 2023
Hang-Tsung Liu,1,* Cheng-Shyuan Rau,2,* Yueh-Wei Liu,3 Ting-Min Hsieh,1 Chun-Ying Huang,1 Peng-Chen Chien,4 Hui-Ping Lin,4 Chia-Jung Wu,4 Pei-Chin Chuang,5 Ching-Hua Hsieh4 1Department of Trauma Surgery, Kaohsiung Chang Gung Memorial Hospital and
Liu HT, Rau CS, Liu YW, Hsieh TM, Huang CY, Chien PC, Lin HP, Wu CJ, Chuang PC, Hsieh CH   +9 more
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