Results 111 to 120 of about 5,629 (182)
N6 adenosine and C5 cytosine modification of mRNAs, tRNAs and rRNAs are regulated by the behaviour of distinct sets of writer, reader and eraser effector proteins which are conventionally considered to function independently. Here, we provide evidence of
Orji, Oliver Chukwuma +5 more
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NSUN2-mediated tRNA methylation is dynamic and site-specific.
, 2019 (A, B) Volcano plot depicting the significant methylation changes when NSUN2 was reexpressed in NSUN2−/− cells compared to empty (‘E.’) vector (A) or K190M controls (B).
Sandra Blanco (34725) +14 more
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Cancer Management and Research, 2021 Li Meng, Qianqian Zhang, Xianghua Huang Department of Gynecology, Hebei Medical University Second Affiliated Hospital, Shijiazhuang, Hebei, 050000, People’s Republic of ChinaCorrespondence: Xianghua HuangDepartment of Gynecology, Hebei Medical University
Meng L, Zhang Q, Huang X
doaj
Cytosine-to-Uracil Deamination by SssI DNA Methyltransferase
, 2013 The prokaryotic DNA(cytosine-5)methyltransferase M.SssI shares the specificity of eukaryotic DNA methyltransferases (CG) and is an important model and experimental tool in the study of eukaryotic DNA methylation.
Stier, Ildikó +5 more
core +1 more source
Elevating RNA m5C methylation provides a promising strategy for crop productivity
Abstract RNA 5-methylcytidine (m5C) has been identified as a key epi-transcriptomic modification of mRNAs involved in regulating multiple post-transcriptional processes. Here, we found that knockout of the RNA m5C demethylase, OsNOP2, results in elevated m5C levels and positively influences numerous agronomic traits in rice.
Xiaofeng Gu +9 more
openaire +1 more source
Advances in research on RNA methylation and cancer radiotherapy resistance
Frontiers in OncologyRNA methylation is a type of reversible chemical modification in epitranscriptomics that influences gene expression by dynamically regulating RNA functions.
Hui Liu +5 more
doaj +1 more source
5-Methylcytosine (m5C) is closely associated with cancer. However, the role of m5C in breast cancer(BC)remains unclear. This study combined single-cell RNA sequencing (scRNA-Seq) and transcriptomics datasets to screen m5C regulators associated with BC ...
Shiming Wang +12 more
core +1 more source
Cancer ControlBackground The aim of this retrospective research was to develop an immune-related genes significantly associated with m5C methylation methylation (m5C-IRGs)-related signature associated with lung adenocarainoma (LUAD).
Xiong Cao +4 more
doaj +1 more source
Identification and validation of novel prognostic signatures based on m5C methylation patterns and tumor EMT profiles in head and neck squamous cell carcinoma. [PDF]
Sci Rep, 2023 Zhu G +8 more
europepmc +1 more source
Comprehensive analysis of m6a and m5c RNA methylation profiles in gliomas
Gliomas are aggressive primary brain tumors with high morbidity and mortality [1]. Despite advances in oncology, their complex biology limits effective treatment options, making gliomas a key focus of cancer research. Epigenetic modifications, including RNA methylation (m6A and 5mC), have been implicated in tumor progression, yet their specific roles ...
Tamašuitytė, Samanta +1 more
openaire +1 more source