Results 141 to 150 of about 5,895 (158)
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Pathology - Research and Practice
Ovarian cancer (OC) is the most dangerous cancer among gynecological tumors, which poses a significant threat to women's health worldwide. 5-methylcytosine (m5C) plays a significant role in regulating tumor development. The RNA methyltransferase Aly/REF export factor (ALYREF) is one of the m5C-modified RNA-reading proteins.
Yongju, Tian +3 more
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Ovarian cancer (OC) is the most dangerous cancer among gynecological tumors, which poses a significant threat to women's health worldwide. 5-methylcytosine (m5C) plays a significant role in regulating tumor development. The RNA methyltransferase Aly/REF export factor (ALYREF) is one of the m5C-modified RNA-reading proteins.
Yongju, Tian +3 more
openaire +2 more sources
Archives of Toxicology
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with a high mortality rate. The 5-methylcytosine (m5C), a type of RNA modification, plays crucial regulatory roles in HCC carcinogenesis, metastasis, and prognosis. However, a few studies have investigated the effect of genetic variants in m5C modification genes on survival of ...
Qiuping Wen +2 more
exaly +3 more sources
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with a high mortality rate. The 5-methylcytosine (m5C), a type of RNA modification, plays crucial regulatory roles in HCC carcinogenesis, metastasis, and prognosis. However, a few studies have investigated the effect of genetic variants in m5C modification genes on survival of ...
Qiuping Wen +2 more
exaly +3 more sources
Journal of Bioenergetics and Biomembranes
Retinoblastoma (RB) is a malignant neoplasm originating from photoreceptor precursor cells that is common in children under 3 years of age. NOP2/Sun RNA methyltransferase family member 2 (NSUN2) is a major methyltransferase that catalyzes mammalian mRNA 5-methylcytosine (m5C) modification and has been implicated in a variety of diseases, but its ...
Jing, Guan, Lili, Lu, Yuantong, Jiang
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Retinoblastoma (RB) is a malignant neoplasm originating from photoreceptor precursor cells that is common in children under 3 years of age. NOP2/Sun RNA methyltransferase family member 2 (NSUN2) is a major methyltransferase that catalyzes mammalian mRNA 5-methylcytosine (m5C) modification and has been implicated in a variety of diseases, but its ...
Jing, Guan, Lili, Lu, Yuantong, Jiang
openaire +2 more sources
Changes of RNA m6A/m5C Modification Regulatory Molecules in Ferroptosis of T2DM Rat Pancreas
Cell Biochemistry and BiophysicsN6-methyladenine (m6A) and 5-methylcytosine (m5C) are two common forms of RNA methylation that play an important role in the epigenetics of type 2 diabetes mellitus (T2DM). One type of cell death, ferroptosis, has been implicated in islet β-cell damage in T2DM.
Xiaoyu Liu +3 more
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NSUN2 Promotes Prostate Cancer Cell Proliferation and Migration Through m5C Modifications of YES1
Molecular CarcinogenesisABSTRACT Prostate cancer (PCa) is one of the most common genitourinary malignancies in men worldwide. As a 5‐methylcytosine (m5C) methyltransferase, NSUN2 has been implicated in regulating PCa progression. This study aimed to investigate the role of NSUN2 in PCa and elucidate its underlying mechanisms.
Tianming Chen +3 more
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Molecular Immunology
Arthritis is an inflammatory disease characterized by multifactorial pathogenesis in joints or surrounding tissues. M1 macrophage polarization is a key pathological feature of arthritis, and m⁵C RNA modification has been implicated in disease progression.
Chunlei, He +7 more
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Arthritis is an inflammatory disease characterized by multifactorial pathogenesis in joints or surrounding tissues. M1 macrophage polarization is a key pathological feature of arthritis, and m⁵C RNA modification has been implicated in disease progression.
Chunlei, He +7 more
openaire +2 more sources
International Immunopharmacology
Osteoarthritis (OA) is characterized by the destruction of chondrocytes, in which chondrocyte pyroptosis has been demonstrated to be a key mechanism driving OA progression. 5-Methylcytosine (m5C) modification has been implicated in various biological processes, yet its role in mediating OA remains poorly understood.
Hainan, Hong +6 more
openaire +2 more sources
Osteoarthritis (OA) is characterized by the destruction of chondrocytes, in which chondrocyte pyroptosis has been demonstrated to be a key mechanism driving OA progression. 5-Methylcytosine (m5C) modification has been implicated in various biological processes, yet its role in mediating OA remains poorly understood.
Hainan, Hong +6 more
openaire +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2022
Haibo Yang, Yumin Wang, Yufei Xiang
exaly
Haibo Yang, Yumin Wang, Yufei Xiang
exaly