Results 151 to 160 of about 8,203 (227)

Targeting YBX1‐m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma

Clinical and Translational Medicine
Background RNA 5‐methylcytosine (m5C) plays an important role in the progression of hepatocellular carcinoma (HCC). Dysregulation of ferroptosis is closely associated with HCC. However, the effect of the epigenetic mRNA m5C modification on ferroptosis in
Ouwen Li, Ke An, Han Wang, Xianbin Li, Yueqin Wang, Lan Huang, Yue Du, Nuo Qin, Jiasheng Dong, Jingyao Wei, Ranran Sun, Yong Shi, Yanjia Guo, Xiangyi Sun, Ying Yang, Yun‐Gui Yang, Quancheng Kan, Xin Tian   +17 more
doaj   +1 more source

m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy

Journal of Experimental & Clinical Cancer Research
Background Lung cancer is the most common malignant tumour and the leading cause of cancer-related death. circular RNAs (circRNAs) have important biological functions and are closely related to tumour development.
Dunyu Cai, Xingcai Chen, Haotian Xu, Qingyun Zhao, Xiaodong Zhou, Jiaxi Wu, Shengyi Yuan, Yihong Gao, Deqing Li, Ruirui Zhang, Wenyi Peng, Gang Li, Aruo Nan   +12 more
doaj   +1 more source

5-Methylcytosine (m5C) modification in peripheral blood immune cells is a novel non-invasive biomarker for colorectal cancer diagnosis

, 2022
Haofan Yin, Zhijian Huang, Shiqiong Niu, Liang Ming, Hong-Bo Jiang, Liang Gu, Weibin Huang, Jinye Xie, Yulong He, Changhua Zhang   +9 more
openalex   +1 more source

CDK13 promotes lipid deposition and prostate cancer progression by stimulating NSUN5-mediated m5C modification of ACC1 mRNA. [PDF]

Cell Death Differ, 2023
Zhang Y, Chen XN, Zhang H, Wen JK, Gao HT, Shi B, Wang DD, Han ZW, Gu JF, Zhao CM, Xue WY, Zhang YP, Qu CB, Yang Z.   +13 more
europepmc   +1 more source

NOP2-mediated m5C Modification of c-Myc in an EIF3A-Dependent Manner to Reprogram Glucose Metabolism and Promote Hepatocellular Carcinoma Progression. [PDF]

Research (Wash D C), 2023
Zhang H, Zhai X, Liu Y, Xia Z, Xia T, Du G, Zhou H, Franziska Strohmer D, Bazhin AV, Li Z, Wang X, Jin B, Guo D.   +12 more
europepmc   +1 more source

CASC19 stabilization by ALYREF via m5C modification and its impact on SCD in colorectal cancer cell aggressiveness and stemness. [PDF]

Cell Biosci
Zhao L, Xie R, Li L, Lu X, Wang L, Wang H, Liu L.   +6 more
europepmc   +1 more source

m5C modification of mRNA serves a DNA damage code to promote homologous recombination [PDF]

, 2020
Hao Chen, Haibo Yang, Xiaolan Zhu, Tribhuwan Yadav, Jian Ouyang, Samuel S. Truesdell, Jun Jie Tan, Yumin Wang, Mei-Han Duan, Leizhen Wei, Lee Zou, Arthur S. Levine, Shobha Vasudevan, Li Lan   +13 more
openalex   +1 more source

LncRNA SLC16A1-AS1 cooperates with NSUN2 to stabilize GRP78 mRNA via m5C modification in gastric cancer. [PDF]

iScience
Zheng B, Zhao W, Jin Y, Sun W, Li Y, Zhang Q, Li Y, Wang J, Chen D, Ren K, Zhang W, Chen Y, Yuan L, Wang XJ, Yang F, Chen J.   +15 more
europepmc   +1 more source

Additional file 4 of NSUN2 restrains gastric cancer cell apoptosis and ferroptosis by promoting the m5C modification of EPYC

Lei Wu, Boxuan Chen, Si Cheng, Xiaofeng Fang, Fen Zhou   +4 more
openalex   +1 more source

Lactylation-driven <i>NSUN2</i>-mediated RNA m5C modification promotes perineural invasion in pancreatic cancer. [PDF]

Theranostics
Huang T, Hu C, Chen H, Jiang H, Li T, Tian Q, He R, Yuan Y, Jiang Y, Zhou Y, Lin Q, Li Z, Xiao M, Wei X, Chen R, Zheng S.   +15 more
europepmc   +1 more source