Results 31 to 40 of about 8,203 (227)

Genetic variants in m5C modification core genes are associated with the risk of Chinese pediatric acute lymphoblastic leukemia: A five-center case-control study. [PDF]

Front Oncol, 2022
Wang X, Deng D, Yan Y, Cai M, Liu X, Luo A, Liu S, Zhang X, Jiang H, Liu X.   +9 more
europepmc   +3 more sources

Integrative 5-Methylcytosine Modification Immunologically Reprograms Tumor Microenvironment Characterizations and Phenotypes of Clear Cell Renal Cell Carcinoma

Frontiers in Cell and Developmental Biology, 2021
The tumor microenvironment (TME) affects the biologic malignancy of clear cell renal cell carcinoma (ccRCC). The influence of the 5-methylcytosine (m5C) epigenetic modification on the TME is unknown.
Wenhao Xu, Wenhao Xu, Wenkai Zhu, Wenkai Zhu, Xi Tian, Xi Tian, Wangrui Liu, Yuanyuan Wu, Aihetaimujiang Anwaier, Aihetaimujiang Anwaier, Jiaqi Su, Jiaqi Su, Shiyin Wei, Yuanyuan Qu, Yuanyuan Qu, Hailiang Zhang, Hailiang Zhang, Dingwei Ye, Dingwei Ye   +18 more
doaj   +1 more source

CNSC-28. THE IMPORTANCE OF M5C RNA MODIFICATIONS IN EPITRANSCRIPTOMICS FOR GLIOBLASTOMA [PDF]

Neuro-Oncology
Abstract Glioblastoma is the most aggressive brain tumor in adults. Despite surgical resection, chemo- and radiotherapies, patients have a median overall survival of less than 2 years. Recently DNA analysis has been developed and defined the characteristics of glioma. Accordingly, the m5C modification on DNA are well reported.
Takahiro Yamamoto, Jin Matsuura, Jun-ichiro Kuroda, Naoki Shinojima, Yu Nagayoshi, Takeshi Chujo, Kazuhito Tomizawa, Akitake Mukasa   +7 more
openalex   +2 more sources

Modification of m5C regulators in sarcoma can guide different immune infiltrations as well as immunotherapy

Frontiers in Surgery, 2023
BackgroundRecent studies have found that 5-methylcytosine (m5C) modulators are associated with the prognosis and treatment of cancer. However, the relevance of m5C modulators in sarcoma prognosis and the tumour microenvironment is unclear.MethodsWe ...
Shusheng Wu, Mengge Li, Rixin Su, Hao Shen, Yifu He, Yangfan Zhou   +5 more
doaj   +1 more source

ALKBH1 knockdown promotes the growth, migration and invasion of HTR-8/SVneo cells through regulating the m5C modification PSMD14. [PDF]

Sci Rep
Zhang C, Li J, Wang L, Yang P, Luo X.
europepmc   +3 more sources

Identification of M5c regulator-medicated methylation modification patterns for prognosis and immune microenvironment in glioma [PDF]

Aging, 2023
Glioma is a common intracranial tumor and is generally associated with poor prognosis. Recently, numerous studies illustrated the importance of 5-methylcytosine (m5C) RNA modification to tumorigenesis. However, the prognostic value and immune correlation of m5C in glioma remain unclear.
Zhenyong Xiao, Jinwei Li, Cong Liang, Yamei Liu, Yuxiu Zhang, Yuxia Zhang, Quan Liu, Xianlei Yan   +7 more
openalex   +3 more sources

ALYREF mediates RNA m⁵C modification to promote hepatocellular carcinoma progression. [PDF]

Signal Transduct Target Ther, 2023
Xue C, Gu X, Zheng Q, Shi Q, Yuan X, Su Y, Jia J, Jiang J, Lu J, Li L.   +9 more
europepmc   +4 more sources

P1250: TRNA METHYLTRANSFERASE DNMT2 MODULATES GVHD PROCESS VIA TRNA M5C MODIFICATION [PDF]

Hemasphere, 2023
Chao M, Guo H, Wang R, Chen T, Zeng Y, Wu S, Yang S, Zhang Y, Zhang X.   +8 more
europepmc   +3 more sources

Advances in RNA cytosine-5 methylation: detection, regulatory mechanisms, biological functions and links to cancer

Biomarker Research, 2020
As an important posttranscriptional modification of RNA, 5-methylcytosine (m5C) has attracted increasing interest recently, with accumulating evidence suggesting the involvement of RNA m5C modification in multiple cellular processes as well as ...
Chen Xue, Yalei Zhao, Lanjuan Li
doaj   +1 more source

m5C Regulator-Mediated Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Papillary Thyroid Carcinoma

Frontiers in Oncology, 2021
Recently, immune response modulation at the epigenetic level is illustrated in studies, but the possible function of RNA 5-methylcytosine (m5C) modification in cell infiltration within the tumor microenvironment (TME) is still unclear.
Fei Li, Qingmei Deng, Xiaoxi Pang, Shan Huang, Jingmiao Zhang, Xiaxia Zhu, Hong Chen, Xiuxia Liu   +7 more
doaj   +1 more source