Results 51 to 60 of about 814,114 (202)

Table_7_Roles of m5C RNA Modification Patterns in Biochemical Recurrence and Tumor Microenvironment Characterization of Prostate Adenocarcinoma.docx

, 2022
BackgroundProstate cancer is the second most common cancer with a high risk of biochemical recurrence (BCR) among men. Recently, 5-methylcytosine (m5C) modification has attracted more attention as a new layer of RNA post-transcriptional regulation. Hence,
Ruiji Liu (11975807), Zhipeng Xu (198453), Yuxi Zhang (212307), Ming Chen (115604), Shuqiu Chen (4595818)   +4 more
core   +1 more source

Identification of M5c regulator-medicated methylation modification patterns for prognosis and immune microenvironment in glioma

Aging, 2023
Glioma is a common intracranial tumor and is generally associated with poor prognosis. Recently, numerous studies illustrated the importance of 5-methylcytosine (m5C) RNA modification to tumorigenesis. However, the prognostic value and immune correlation of m5C in glioma remain unclear.
Xiao, Zhenyong, Li, Jinwei, Liang, Cong, Liu, Yamei, Zhang, Yuxiu, Zhang, Yuxia, Liu, Quan, Yan, Xianlei   +7 more
openaire   +2 more sources

Aberrant m5C hypermethylation mediates intrinsic resistance to gefitinib through NSUN2/YBX1/QSOX1 axis in EGFR-mutant non-small-cell lung cancer

Molecular Cancer, 2023
Background RNA 5-methylcytosine (m5C) modification plays critical roles in the pathogenesis of various tumors. However, the function and molecular mechanism of RNA m5C modification in tumor drug resistance remain unclear.
Yueqin Wang, Jingyao Wei, Luyao Feng, Ouwen Li, Lan Huang, Shaoxuan Zhou, Yingjie Xu, Ke An, Yu Zhang, Ruiying Chen, Lulu He, Qiming Wang, Han Wang, Yue Du, Ruijuan Liu, Chunmin Huang, Xiaojian Zhang, Yun-gui Yang, Quancheng Kan, Xin Tian   +19 more
doaj   +1 more source

Comprehensive Analysis of 5-Methylcytosine (m5C) Regulators and the Immune Microenvironment in Pancreatic Adenocarcinoma to Aid Immunotherapy

Frontiers in Oncology, 2022
BackgroundPancreatic adenocarcinoma (PAAD) is one of the most malignant cancers and has a poor prognosis. As a critical RNA modification, 5-methylcytosine (m5C) has been reported to regulate tumor progression, including PAAD progression.
Ronglin Wang, Yongdong Guo, Peixiang Ma, Yang Song, Jie Min, Ting Zhao, Lei Hua, Chao Zhang, Cheng Yang, Jingjie Shi, Liaoliao Zhu, Dongxue Gan, Shanshan Li, Junqiang Li, Haichuan Su   +14 more
doaj   +1 more source

Image_6_Roles of m5C RNA Modification Patterns in Biochemical Recurrence and Tumor Microenvironment Characterization of Prostate Adenocarcinoma.tif

, 2022
BackgroundProstate cancer is the second most common cancer with a high risk of biochemical recurrence (BCR) among men. Recently, 5-methylcytosine (m5C) modification has attracted more attention as a new layer of RNA post-transcriptional regulation. Hence,
Ruiji Liu (11975807), Zhipeng Xu (198453), Yuxi Zhang (212307), Ming Chen (115604), Shuqiu Chen (4595818)   +4 more
core   +1 more source

Landscape analysis of m5C modification regulators unveils DNMT1-mediated dysregulated pyrimidine metabolism in hepatocellular carcinoma. [PDF]

Clin Epigenetics
The 5-methylcytosine (m5C) post-transcriptional modification has been linked with the development and progression of a variety of cancers. However, its specific functions and their underlying mechanisms are poorly understood in hepatocellular carcinoma ...
Zhao X, Mao S, Fang Y, Chen J, Bi L, Li J, Wu J, Gao J, Yang S, Fu J, Wu X, Zhu G, Tang Z, Shi Y, Zhou J, Fan J, Zhang X, Jiang J, Liu W.   +18 more
europepmc   +2 more sources

Table_6_Roles of m5C RNA Modification Patterns in Biochemical Recurrence and Tumor Microenvironment Characterization of Prostate Adenocarcinoma.xlsx

, 2022
BackgroundProstate cancer is the second most common cancer with a high risk of biochemical recurrence (BCR) among men. Recently, 5-methylcytosine (m5C) modification has attracted more attention as a new layer of RNA post-transcriptional regulation. Hence,
Ruiji Liu (11975807), Zhipeng Xu (198453), Yuxi Zhang (212307), Ming Chen (115604), Shuqiu Chen (4595818)   +4 more
core   +1 more source

Molecular Characterization and Clinical Characteristics of m5C-Based RNA Methylation in Spinal Cord Injury: Validated by qPCR

International Journal of Genomics, 2022
Aberrant patterns of 5-methylcytosine (m5C)-based ribonucleic acid (RNA) methylation have critical roles in various human diseases, but their importance in spinal cord injury (SCI) is largely unknown.
Liang Cao, Wen Jun Pi, Qiang Zhang, Qing Li   +3 more
doaj   +1 more source

Table_3_Roles of m5C RNA Modification Patterns in Biochemical Recurrence and Tumor Microenvironment Characterization of Prostate Adenocarcinoma.xlsx

, 2022
BackgroundProstate cancer is the second most common cancer with a high risk of biochemical recurrence (BCR) among men. Recently, 5-methylcytosine (m5C) modification has attracted more attention as a new layer of RNA post-transcriptional regulation. Hence,
Ruiji Liu (11975807), Zhipeng Xu (198453), Yuxi Zhang (212307), Ming Chen (115604), Shuqiu Chen (4595818)   +4 more
core   +1 more source

Biological functions of 5-methylcytosine RNA-binding proteins and their potential mechanisms in human cancers

Frontiers in Oncology
The 5-methylcytosine (m5C) modification is a crucial epigenetic RNA modification, which is involved in the post-transcriptional regulation of genes. It plays an important role in various biological processes, including cell metabolism, growth, apoptosis,
Tingting Zhao, Zhe Zhang, Zhuo Chen, Guozheng Xu, Yongxi Wang, Fang Wang   +5 more
doaj   +1 more source