Results 1 to 10 of about 26,139 (253)
The role of RNA m6A methylation in lipid metabolism
Frontiers in Endocrinology, 2022 The m6A methylation is the most numerous modification of mRNA in mammals, coordinated by RNA m6A methyltransferases, RNA m6A demethylases, and RNA m6A binding proteins. They change the RNA m6A methylation level in their specific manner.
Yuting Wang +5 more
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LncRNAs and Chromatin Modifications Pattern m6A Methylation at the Untranslated Regions of mRNAs
Frontiers in Genetics, 2022 New roles for RNA in mediating gene expression are being discovered at an alarming rate. A broad array of pathways control patterning of N6-methyladenosine (m6A) methylation on RNA transcripts.
Lee O. Vaasjo, Lee O. Vaasjo
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IET Systems Biology, 2022 N6âmethyladenosine (m6A) RNA methylation is correlated with carcinogenesis and dynamically possessed through the m6A RNA methylation regulators. This paper aimed to explore 13 m6A RNA methylation regulators' role in gastrointestinal cancer (GIC) and ...
Yandong Miao +6 more
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The Reversible Methylation of m6A Is Involved in Plant Virus Infection
Biology, 2022 In recent years, m6A RNA methylation has attracted broad interest and is becoming a hot research topic. It has been demonstrated that there is a strong association between m6A and viral infection in the human system.
Jianying Yue, Yao Wei, Mingmin Zhao
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Arthritis Research & Therapy, 2023 Background N6-methyladenosine (m6A) methylation modification is involved in the regulation of various biological processes, including inflammation, antitumor, and antiviral immunity. However, the role of m6A modification in the pathogenesis of autoimmune
Yurong Huang +7 more
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Frontiers in Genetics, 2021 Background: N6-Methyladenosine (m6A) methylation is the most prevalent internal posttranscriptional modification on mammalian mRNA. But its role in neuromyelitis optica spectrum disorders (NMOSD) is not known.Aims: To explore the mechanism of m6A in ...
Hong Yang +7 more
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N6-Methyladenosine Regulators Promote Malignant Progression of Gastric Adenocarcinoma
Frontiers in Oncology, 2022 N6-methyladenosine (m6A) RNA methylation is dynamically and reversibly regulated by methyltransferases, binding proteins, and demethylases. The restoration of m6A to adenosine could result in demethylation modifications.
Yibin Zhao +4 more
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Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification [PDF]
, 2020 Understanding genome organization and gene regulation requires insight into RNA transcription, processing and modification. We adapted nanopore direct RNA sequencing to examine RNA from a wild-type accession of the model plant Arabidopsis thaliana and a ...
Barton, Geoffrey J. +8 more
core +3 more sources
The role m6A RNA methylation is CNS development and glioma pathogenesis
Molecular Brain, 2021 Epigenetic abnormalities play a crucial role in many tumors, including glioma. RNA methylation occurs as an epigenetic modification similar to DNA methylation and histone modification.
Ting Pan +7 more
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Emerging Roles and Mechanism of m6A Methylation in Cardiometabolic Diseases
Cells, 2022 Cardiometabolic diseases (CMDs) are currently the leading cause of death and disability worldwide, and their underlying regulatory mechanisms remain largely unknown.
Zujie Xu +3 more
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