Results 21 to 30 of about 10,766 (255)

Invariant Natural Killer T and Mucosal-Associated Invariant T Cells in Asthmatic Patients [PDF]

Frontiers in Immunology, 2018
Recent studies have highlighted the heterogeneity of asthma. Distinct patient phenotypes (symptoms, age at onset, atopy, and lung function) may result from different pathogenic mechanisms, including airway inflammation, remodeling, and immune and ...
Guillaume Lezmi, Guillaume Lezmi, Guillaume Lezmi, Maria Leite-de-Moraes, Maria Leite-de-Moraes   +4 more
doaj   +3 more sources

Varicella Zoster Virus infects mucosal associated Invariant T cells [PDF]

Frontiers in Immunology, 2023
IntroductionMucosal Associated Invariant T (MAIT) cells are innate-like T cells that respond to conserved pathogen-derived vitamin B metabolites presented by the MHC class I related-1 molecule (MR1) antigen presentation pathway.
Shivam K. Purohit, Alexandra J. Corbett, Barry Slobedman, Allison Abendroth   +3 more
doaj   +2 more sources

Characterization of human Mucosal-associated Invariant T (MAIT) cells

Current Protocols in Immunology, 2019
Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells restricted by the major histocompatibility complex (MHC) class I–like molecule MHC-related protein 1 (MR1).
Fairlie, David P., Godfrey, DI, Chen, Z, Pellicci, DG, Shihan Li, Gherardin, Nicholas A., McCluskey, James, Godfrey, Dale I., Kjer-Nielsen, Lars, Gherardin, NA, Nicholas A. Gherardin, Meehan, BS, Dale I. Godfrey, Corbett, AJ, Kedzierska, Katherine, Chen, Zhenjun, Bronwyn S. Meehan, McCluskey, J, Lars Kjer‐Nielsen, Eckle, Sidonia B. G., Liyen Loh, Fairlie, DP, Sidonia B. G. Eckle, Alexandra J. Corbett, Souter, Michael N.T., Rossjohn, J, Jamie Rossjohn, Eckle, SBG, Corbett, Alexandra J., Zhenjun Chen, Loh, Liyen, Loh, L, Souter, MNT, Katherine Kedzierska, Li, Shihan, Meehan, Bronwyn S., Rossjohn, Jamie, Kjer-Nielsen, L, Daniel G. Pellicci, Michael N.T. Souter, James McCluskey, Pellicci, Daniel G., David P. Fairlie, Li, S, Kedzierska, K   +44 more
core   +6 more sources

Natural Killer T Cells and Mucosal-Associated Invariant T Cells in Lung Infections [PDF]

Frontiers in Immunology, 2018
The immune system has been traditionally divided into two arms called innate and adaptive immunity. Typically, innate immunity refers to rapid defense mechanisms that set in motion within minutes to hours following an insult.
François Trottein, François Trottein, François Trottein, François Trottein, François Trottein, Christophe Paget, Christophe Paget   +6 more
doaj   +4 more sources

Estrogen Induced Regulation of Mucosal-Associated Invariant T Cells in Asthma [PDF]

Journal of Immunology Research
Asthma affects over 300 million people worldwide, with increasing rates annually. Males have higher asthma prevalence in adolescence, while females exhibit higher rates in adulthood. Reduced mucosal-associated invariant T (MAIT) cells are found in severe
Shubhanshi Trivedi, Samuel E. Aamodt, Thomas P. Huecksteadt, Elizabeth J. Myers, Grace Helen McGee, Jackson G. Cacioppo, Jeffrey Aubé, Robert Paine, Daniel T. Leung, Kristi J. Warren   +9 more
doaj   +2 more sources

The Role of Mucosal-Associated Invariant T Cells in Viral Infections and Their Function in Vaccine Development [PDF]

Vaccines
Mucosal-Associated Invariant T (MAIT) cells, which bridge innate and adaptive immunity, have emerged as an important player in viral infections despite their inability to directly recognize viral antigens. This review provides a comprehensive analysis of
Chie Sugimoto, Hiroshi Wakao
doaj   +2 more sources

Mucosal-associated invariant T cells and disease [PDF]

Nature Reviews Immunology, 2019
International audienceMucosal-associated invariant T (MAIT) cells are unique innate-like T cells that bridge innate and adaptive immunity. They are activated by conserved bacterial ligands derived from vitamin B biosynthesis and have important roles in ...
Lotersztajn, Sophie, Nel, Isabelle, Toubal, Amine, Lehuen, Agnès   +3 more
core   +4 more sources

Mucosal‐Associated Invariant T Cells: Origins, Biological Functions, Diseases, and Therapeutic Targets [PDF]

MedComm
Mucosal‐associated invariant T (MAIT) cells are a highly conserved population of immune cells that can be activated via the major histocompatibility complex class I‐related protein pathway or cytokine pathways, playing a central role in immune ...
Cheng Zhu, Qian Huai, Yishan Du, Xingyu Li, Fumin Zhang, Yongkang Zhang, Mengwei Wu, Ying Dai, Xiaolei Li, Hanren Dai, Hua Wang   +10 more
doaj   +2 more sources

Invariant natural killer T cells and mucosal-associated invariant T cells in multiple sclerosis

Immunology Letters, 2017
Multiple sclerosis (MS) is a chronic progressive inflammatory demyelinating disorder of the central nervous system, and in several countries is a leading cause of permanent neurological disability in young adults, particularly women.
PINTI, Marcello, FERRARO, Diana, COSSARIZZA, Andrea, BIANCHINI, ELENA, SIMONE, ANNA MARIA, Sola, Patrizia, DE BIASI, SARA   +6 more
core   +3 more sources

B cells modulate mucosal associated invariant T cell (MAIT) immune responses [PDF]

Frontiers in Immunology, 2014
A common finding when measuring T cell immunity to enteric bacterial vaccines in humans is the presence of background responses among individuals before immunization. Yet the nature of these background responses remains largely unknown. Recent findings
Rosangela eSalerno-Goncalves, Tasmia eRezwan, Marcelo B. Sztein   +2 more
doaj   +3 more sources