Results 51 to 60 of about 5,285 (165)

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, Volume 183, Issue 14, Page 3897-3919, July 2026.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Defining the end point of status epilepticus: A scoping review and framework for standardization

Epilepsia, Volume 67, Issue 6, Page 2673-2688, June 2026.
Abstract Status epilepticus (SE) is a life‐threatening neurological emergency with consensus‐driven definitions for onset but no standardized criteria for its end point. This gap creates uncertainty in research and clinical practice. We conducted a scoping review to evaluate how end points have been defined in SE research and to identify key areas of ...
Fawad A. Khan, Margaret T. Gopaul, Samuel L. Carter, Anil Chimakurthy, Summer Skelton, Lawrence J. Hirsch, Eugen Trinka   +6 more
wiley   +1 more source

Women with epilepsy: Evidence‐based counseling across the lifespan

Epilepsia, Volume 67, Issue 6, Page 2689-2706, June 2026.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn, Georgia Ramantani, Dominique Flügel, Verena Gaus, Susanne Schubert‐Bast, Elisabeth Sellitto, Jennifer Bausch, Bettina Schmitz   +7 more
wiley   +1 more source

An iEEG investigation on sex‐specific differences in seizure duration

Epilepsia Open, Volume 11, Issue 3, Page 912-921, June 2026.
Abstract Objective Male people with epilepsy (mPWE) are at higher risk for bilateral tonic–clonic seizures (BTCs) and sudden unexpected death in epilepsy (SUDEP) compared to female people with epilepsy (fPWE). Despite major clinical and personal implications, little is known about sex‐specific differences in seizure propagation and termination ...
Paula Albert I Gracenea, Alexandra Muss, Magdalena Seethaler, Jan Rémi, Elisabeth Kaufmann   +4 more
wiley   +1 more source

Precursors of the neurosteroids. [PDF]

Proceedings of the National Academy of Sciences, 1994
In addition to the neurosteroids pregnenolone and dehydroepiandrosterone, organic solvent extracts of rat brains contain related compounds that react with various reagents to yield additional amounts of these ketosteroids. Among the chemicals producing these increments are triethylamine, HCl, FeCl3, and Pb(OAc)4.
V V, Prasad, S R, Vegesna, M, Welch, S, Lieberman   +3 more
openaire   +2 more sources

Psychosocial and menstrual correlates of premenstrual disorders: A community‐based study

International Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1472-1479, June 2026.
Abstract Objective To assess the background, psychosocial, and menstrual factors associated with premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) in a community‐based cohort. Methods A prospective cohort study was conducted using data from users of a menstrual tracking application.
Shiori Itoi, Makiko Sampei, Takayuki Tatsumi, Yutaka Osuga, Kaori Koga, Satoshi Narumi, Naho Morisaki   +6 more
wiley   +1 more source

Mitigation of Cisplatin‐Induced Neurotoxicity via Nrf2/HO‐1 Signaling and Autophagy: The Protective Role of Vitamin D

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This study investigates the neuroprotective effect of vitamin D against cisplatin‐induced mitochondrial damage and oxidative stress (ROS). HO‐1 expression is increased by vitamin D, which triggers Nrf2 activation and nuclear translocation. The results demonstrate that vitamin D protects brain tissue by strengthening the antioxidant defense system ...
Songul Cuglan, Azibe Yildiz, Kevser Tanbek   +2 more
wiley   +1 more source

Formulation and Pharmacological Evaluation of a Medicine‐Food Homology Herb‐Based Formula for Sleep Enhancement

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
This outlines the progress for developing a sleep‐modulating herbal formula (SMF). It begins with the identification of effective compounds and quality control, then uses network pharmacology and molecular docking to explain the mechanisms behind the observation found on the behavioural and neurobiological results in animal study.
Jasmine U. Ting, Chunxue Zhao, Jia Xu, Chenrui Liu, Yungang Tian, Min Ye, Tao Cui, Jian Huang   +7 more
wiley   +1 more source

Neurosteroids for a successful pregnancy

Stress, 2010
Steroid hormones play a critical role in the initiation and maintenance of pregnancy. In particular, the important role that the progesterone metabolite, and neurosteroid, allopregnanolone, may play in fetal and adolescent development is becoming increasingly evident.
Cheryl A, Frye, Jonathan J, Hirst, Paula J, Brunton, John A, Russell   +3 more
openaire   +2 more sources

7alpha-Hydroxypregnenolone, a new key regulator of locomotor activity of vertebrates: Identification, mode of action and functional significance

Frontiers in Endocrinology, 2010
Steroids synthesized de novo by the central and peripheral nervous systems are called neurosteroids. The formation of neurosteroids from cholesterol in the brain was originally demonstrated in mammals by Baulieu and colleagues.
Kazuyoshi eTsutsui, Shogo eHaraguchi, Masahiro eMatsunaga, Kazuhiko eInoue, Kazuhiko eInoue, Hubert eVaudry   +5 more
doaj   +1 more source