Results 51 to 60 of about 12,871 (217)
Site-specific effects of neurosteroids on GABAA receptor activation and desensitization
bioRxiv, 2020 This study examines how site-specific binding to the three identified neurosteroid binding sites in the α1β3 GABAA receptor (GABAAR) contributes to neurosteroid allosteric modulation. We found that the potentiating neurosteroid, allopregnanolone, but not
Yusuke Sugasawa +12 more
semanticscholar +1 more source
Neurosteroid biosynthesis and function in the brain of domestic birds
Frontiers in Endocrinology, 2011 It is now established that the brain and other nervous systems have the capability of forming steroids de novo, the so-called neurosteroids. The pioneering discovery of Baulieu and his colleagues, using rodents, has opened the door to a new research ...
Kazuyoshi eTsutsui
doaj +1 more source
Neurosteroids in developmental disorders
, 1998 Steroids play several vital roles in the central nervous system. Some of these steroids, called neurosteroids, are synthesized within the brain by the glial cells. The main neurosteroid is allopregnanolone, a metabolite of progesterone.
CURATOLO, PAOLO +3 more
core +2 more sources
Functional Food Nutrients, Redox Resilience Signaling and Neurosteroids for Brain Health
International Journal of Molecular SciencesThe interplay between functional food nutrients and neurosteroids has garnered significant attention for its potential to enhance stress resilience in health and/or disease.
M. Scuto +6 more
semanticscholar +1 more source
Sexual steroids and functions of the brain [PDF]
Гинекология, 2017 Neurosteroids are endogenous modulators of nervous excitability. There is increasing evidence of sedative, anxiolytic, analgesic and anticonvulsant properties of neurosteroids.
N N Stenyaeva +3 more
doaj
The brain of teleost fish, a source and a target of sexual steroids
Frontiers in Neuroscience, 2011 Neurosteroids are defined as steroids de novo synthesized in the central nervous system. While the production of neurosteroids is well documented in mammals or amphibians, there is little information in teleosts, the largest group of fish.
Nicolas eDiotel +6 more
doaj +1 more source
Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms
Epilepsia, EarlyView.Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong +4 more
wiley +1 more source
Neurosteroids and Psychiatric Disorders
, 2022 Neurosteroids and Psychiatric ...
Giovana Bristot (13744825) +5 more
core
Neuroprotective actions of cerebellar and pineal allopregnanolone on Purkinje cells
FASEB BioAdvances, 2020 The brain produces steroids de novo from cholesterol, so‐called “neurosteroids.” The Purkinje cell, a cerebellar neuron, was discovered as a major site of the biosynthesis of neurosteroids including sex steroids, such as progesterone, from cholesterol in
Kazuyoshi Tsutsui, Shogo Haraguchi
doaj +1 more source
Cells, 2020 Neuroinflammation, whose distinctive sign is the activation of microglia, is supposed to play a key role in the development and progression of neurodegenerative diseases.
Rossella Avallone +7 more
doaj +1 more source