Results 81 to 90 of about 381,426 (191)
Frontiers in ImmunologyBackgroundHelicobacter pylori (H. pylori) uses various strategies that attenuate mucosal immunity to ensure its persistence in the stomach. We recently found evidence that H. pylori might modulate the natural killer group 2, member 2 (NKG2D) system.
Margit Anthofer +18 more
doaj +1 more source
The Paradoxical Role of NKG2D in Cancer Immunity
Frontiers in Immunology, 2018 The activating receptor NKG2D and its ligands are recognized as a potent immune axis that controls tumor growth and microbial infections. With regards to cancer surveillance, various studies have demonstrated the antitumor function mediated by NKG2D on ...
Sam Sheppard +4 more
doaj +1 more source
Understanding Exosomes in Hair Regeneration
Periodontology 2000, EarlyView.Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad +3 more
wiley +1 more source
BiomedicinesNKG2D is an activating receptor expressed by all human NK cells and CD8 T cells. Harnessing the NKG2D/NKG2D ligand axis has emerged as a viable avenue for cancer immunotherapy.
Anthony V. Serritella +7 more
doaj +1 more source
The osteoimmune cell atlas of peri‐implantitis: A narrative scoping review
Periodontology 2000, EarlyView.Abstract Background/Aim Peri‐implantitis represents a complex osteoimmune disorder characterized by dysregulated cellular ecosystems that drive chronic inflammation and accelerated peri‐implant bone loss. Materials and Methods This article was designed as a narrative scoping review to map and integrate the available evidence from transcriptomics ...
Emilio A. Cafferata +2 more
wiley +1 more source
The immunoreceptor NKG2D promotes tumour growth in a model of hepatocellular carcinoma
Nature Communications, 2017 Expression of NKG2D immunoreceptor ligands on tumour cells is believed to inhibit tumour growth through engaging NKG2D-expressing immune cells. Here, the authors show that in a model of liver cancer the NKG2D/NKG2D-ligand pathway can also promote tumour ...
Sam Sheppard +8 more
doaj +1 more source
Quantification of Rae-1 Staining Intensity in Glomeruli
Bio-Protocol, 2016 NKG2D is expressed on all NK cells and on subsets of NKT, CD8, CD4 and γδ T cells. NKG2D is activated by NKG2D ligands, a stress-induced family of MHC-I-like proteins.
Roberto Spada, Domingo Barber
doaj +1 more source
British Journal of Pharmacology, Volume 183, Issue 21, Page 6261-6290, November 2026.Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley +1 more source
, 2016 It is now clear that recognition of nascent tumors by the immune system is critical for survival of the host against cancer. During cancer immunoediting, the ability of the tumor to escape immune recognition is important for tumor development. The immune
Polić, Bojan, Raju, Saravanan
core +1 more source
Natural Killer Group 2, Member D/NKG2D Ligands in Hematopoietic Cell Transplantation [PDF]
, 2017 Natural killer group 2, member D (NKG2D) is an invariant activatory receptor present on subsets of natural killer and T lymphocytes. It stimulates the cytolytic effector response upon engagement of its various stress-induced ligands NKG2D ligands (NKG2DL)
Raphael Carapito +11 more
core +1 more source