Results 131 to 140 of about 2,920 (152)

m5C RNA methylation is dysregulated by oncogenic herpesviruses via c-Myc signaling to counteract host antiviral factors. [PDF]

Nucleic Acids Res
Wu Z, Liu Y, Zhou D, He Z, Fiches GN, Park Y, Zhu A, He J, Chen J, Shanaka KASN, Lepcha TT, Desai P, Zhu J, Santoso NG.   +13 more
europepmc   +1 more source

The RNA methyltransferase NSUN2 catalyzes 5-methylcytosine (m⁵C) on IL1B mRNA to promote transcript stability. [PDF]

J Biol Chem
Wang J, Yan L, Jia R, Guo J.
europepmc   +1 more source

N6-Methyladenosine and 5-Methylcytosine Epitranscriptomic Regulation of Male Reproduction and Fertility. [PDF]

Biology (Basel)
Salih SM, Al-Hendy A, Yang Q.
europepmc   +1 more source

Global research trends on the relationship between RNA m⁵C modification and cancer progression: a comprehensive visualization and bibliometric analysis (1900-2024). [PDF]

Biophys Rep
Yao P, Chen F, Zhang N, Ullah H, Shi X, Zhong X, Zhou L.   +6 more
europepmc   +1 more source

ALYREF-mediated RNA 5-methylcytosine modification promotes laryngeal cancer progression via stabilizing DDX11 mRNA. [PDF]

Sci Rep
Bian S, Li R, Guo Y, Wu Y, Zhao J, Wang Z, Huang J.   +6 more
europepmc   +1 more source

Deep learning model and omics screening highlight angiotensinogen as a 5-methylcytosine (m⁵C) regulated mediator of tumor-microenvironment communication in liver cancer. [PDF]

Front Immunol
Pang H, Wang L, Li Y, Zhou Y.
europepmc   +1 more source

Emerging roles of RNA N5-methylcytosine modification in reproductive physiology and gynecological diseases. [PDF]

Epigenetics
Lv F, Jin Y, Yu S, Yang X, Xia S, Ye X, Zhao Q, Hu Y, Zheng A, Wu Y, Tong J.   +10 more
europepmc   +1 more source

Oncogenic and immunological roles of NSUN2 in triple negative breast cancer. [PDF]

Sci Rep
An N, Zeng YF, Tian ZW, Tian J, Xu LF, Yang YL, Zheng HM, Zhang JW, Xi YQ.   +8 more
europepmc   +1 more source

Reorganization of the Landscape of Translated mRNAs in NSUN2-Deficient Cells and Specific Features of NSUN2 Target mRNAs

International Journal of Molecular Sciences, 2022
The RNA cytosine C5 methyltransferase NSUN2 has a variety of RNA substrates and plays an important role in mRNA metabolism. NSUN2 binds to specific sequences enriched in exosomal mRNAs, suggesting its possible involvement in the sorting of mRNAs into ...
Galina Karpova, Alexey Malygin, Alexander V Gopanenko   +2 more
exaly   +2 more sources

RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation [PDF]

Acta Neuropathologica, 2022
Epitranscriptomic regulation adds a layer of post-transcriptional control to brain function during development and adulthood. The identification of RNA-modifying enzymes has opened the possibility of investigating the role epitranscriptomic changes ...
Gunnar Hargus, Ismael Santa-Maria Perez, Tohid Siddiqui   +2 more
exaly   +2 more sources