Results 131 to 140 of about 3,656 (193)

NSUN2-mediated HCV RNA m5C Methylation Facilitates Viral RNA Stability and Replication

Genomics, Proteomics & Bioinformatics
Abstract RNA modifications have emerged as new efficient targets against viruses. However, little is known about 5-methylcytosine (m5C) modification in the genomes of flaviviruses. Herein, we demonstrate that hepatitis C virus (HCV), dengue virus, and Zika virus exhibit high levels of viral RNA m5C modification. We identified an m5C site
Zhu-Li Li, Yan Xie, Yafen Wang, Jing Wang, Xiang Zhou, Xiao-Lian Zhang   +5 more
openaire   +2 more sources

Post-transcriptional modifications to tRNA--a response to the genetic code degeneracy. [PDF]

, 2015
,, Hou, Ya-Ming, Yang, Wei
core   +3 more sources

Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis [PDF]

, 2015

core   +1 more source

NSUN2 mediates intestinal stem cell expansion and colorectal tumour initiation via MAPK/ERK signalling. [PDF]

Cell Death Dis
Bastem Akan A, Billard CV, Chen SY, Huang PH, Cammareri P, Rajasekaran V, Hall AE, Preyzner P, Pohl SÖ, Farrington SM, Dunlop MG, Din FVN, Myant KB.   +12 more
europepmc   +1 more source

NSUN2 promoted tumor growth and metastatic via m⁵C-regulation of YAP through ALYREF/YBX1 axis in NSCLC. [PDF]

Cell Death Dis
Li R, Jin D, Shao S, Guo J.
europepmc   +1 more source

Microarray analysis revealed different gene expression patterns in HepG2 cells treated with low and high concentrations of the extracts of Anacardium occidentale shoots [PDF]

, 2011
Shaghayegh Khaleghi, Azlina Abdul Aziz, Nurhanani Razali, Sarni Mat Junit   +3 more
core   +1 more source

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP-9. [PDF]

Oncol Lett
Luo J, Li G, Ye M, Xu X, Qi M, Huang J, Shan K, Qu L, Shi H.   +8 more
europepmc   +1 more source

m5C RNA methylation is dysregulated by oncogenic herpesviruses via c-Myc signaling to counteract host antiviral factors. [PDF]

Nucleic Acids Res
Wu Z, Liu Y, Zhou D, He Z, Fiches GN, Park Y, Zhu A, He J, Chen J, Shanaka KASN, Lepcha TT, Desai P, Zhu J, Santoso NG.   +13 more
europepmc   +1 more source

Deep learning model and omics screening highlight angiotensinogen as a 5-methylcytosine (m⁵C) regulated mediator of tumor-microenvironment communication in liver cancer. [PDF]

Front Immunol
Pang H, Wang L, Li Y, Zhou Y.
europepmc   +1 more source

Emerging roles of RNA N5-methylcytosine modification in reproductive physiology and gynecological diseases. [PDF]

Epigenetics
Lv F, Jin Y, Yu S, Yang X, Xia S, Ye X, Zhao Q, Hu Y, Zheng A, Wu Y, Tong J.   +10 more
europepmc   +1 more source