Results 51 to 60 of about 52,257,618 (175)

The hazard of carbapenemase (OXA-181)-producing Escherichia coli spreading in pig and veal calf holdings in Italy in the genomics era: Risk of spill over and spill back between humans and animals

Frontiers in Microbiology, 2022
Carbapenemase-producing Enterobacterales (CPE) are considered a major public health issue. In the frame of the EU Harmonized AMR Monitoring program conducted in Italy in 2021, 21 epidemiological units of fattening pigs (6.98%; 95% CI 4.37–10.47%; 21/301)
Virginia Carfora, Elena Lavinia Diaconu, Angela Ianzano, Paola Di Matteo, Roberta Amoruso, Elena Dell'Aira, Luigi Sorbara, Francesco Bottoni, Flavia Guarneri, Laura Campana, Alessia Franco, Patricia Alba, Antonio Battisti   +12 more
doaj   +1 more source

NDM-1 and OXA-48-Like Carbapenemases (OXA-48, OXA-181 and OXA-252) Co-Producing Shewanella xiamenensis from Hospital Wastewater, China

Infection and Drug Resistance, 2022
Yicheng Wen,1,* Xiaofang Xie,1,* Ping Xu,2,* Chengcheng Yang,1 Zhichen Zhu,1 Jie Zhu,1 Jingnan Lv,1 Haifang Zhang,1 Liang Chen,3,4 Hong Du1 1Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou ...
Wen Y, Xie X, Xu P, Yang C, Zhu Z, Zhu J, Lv J, Zhang H, Chen L, Du H   +9 more
doaj  

Investigation Of Bla(Oxa-48)-Like Genes İn Carbapenemase Producing Klebsiella Spp. Isolates [PDF]

, 2019
The emergence and spread of multi-drug-resistant (MDR), extended-spectrum beta-lactamase (ESBL) producing carbapenem-resistant members of Enterobacteriaceae family has become a worldwide health problem.
Elmas Pinar Kahraman, Altındiş, Mustafa, Baris Otlu, Toptan, Hande, Köroğlu, Mehmet, Otlu, Barış, Sakarya Üniversitesi/Tıp Fakültesi/Temel Tıp Bilimleri Bölümü, Kahraman, Elmas Pınar   +7 more
core   +1 more source

Evaluation of CHROMagar™mSuperCARBA™ as a Phenotypic Test for Detection of Carbapenemase Producing Organisms [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Carbapenem resistance among Enterobacteriaceae continues to escalate. Carbapenemase encoding genes borne on plasmids leads to wide-spread transmission among Enterobacteriaceae.
Anushree Ulhas Amladi, Thambu David Sudarsanam, Subramani Kandasamy, Nitin Kekre, Balaji Veeraraghavan, Rani Diana Sahni   +5 more
doaj   +1 more source

Supramolecular Cadmium‐Telluride Proteoliposomal Assemblies for Real‐Time Detection of Protein‐Catalyzed Pt(II)‐Complexes Transmembrane Translocation: Cu(I)‐Pumps Are Electrogenic Pt(II)‐Drug Uniporters

Angewandte Chemie, EarlyView.
Supramolecular mercaptosuccinic acid‐capped CdTe core‐type quantum dot‐encapsulated proteoliposome assemblies (MSA‐CdTe QD PLs) have been developed to study and unambiguously demonstrate real‐time transporter‐mediated turnover translocation of Pt(II)‐based complexes by transmembrane Cu(I) P‐type ATPase pumps (CopA).
Madujika A. Horadigala Gamage, Alessandra Barbanente, Nadeesha T. Liyana Withanage, Yalini H. Wijesundara, Jeremiah J. Gassensmith, Fabio Arnesano, Giovanni Natile, Gabriele Meloni   +7 more
wiley   +2 more sources

OXA-48-like carbapenemases in the UK: an analysis of isolates and cases from 2007 to 2014 [PDF]

Journal of Antimicrobial Chemotherapy, 2017
OXA-48-like carbapenemases have spread worldwide since 2001. We analysed patient and microbiological data for UK isolates with these enzymes as confirmed by the national reference laboratory from November 2007 to December 2014.MICs were determined using BSAC agar dilution.
Findlay, Jacqueline, Hopkins, Katie L, Loy, Richard, Doumith, Michel, Meunier, Danièle, Hill, Robert, Pike, Rachel, Mustafa, Nazim, Livermore, David M, Woodford, Neil   +9 more
openaire   +4 more sources

Molecular Glue Degraders of TEM β‐Lactamases by Periplasmic Protease DegP

Angewandte Chemie, EarlyView.
Molecular glues are developed that target TEM‐family β‐lactamases to the bacterial protease DegP for degradation. β‐Lactamase inhibitor tazobactam is identified as accelerating TEM β‐lactamase degradation by DegP, which is further enhanced by linkerless incorporation of dipeptides enriched among DegP substrates.
Emilia K. Taylor, Patricia Santos Barbosa, Tarini Kadambi, Frederik Eisele, Yiqiao Wang, Elisabete C. C. M. Moura, Timothy R. Walsh, Georgia L. Isom, Thomas Lanyon‐Hogg   +8 more
wiley   +2 more sources

Rising Threat of OXA-48 and other Carbapenemase Encoding Genes among Carbapenem Resistant Enterobacteriaceae in India

Journal of Pure and Applied Microbiology, 2020
Members of Enterobacteriaceae family are responsible for both community and hospital acquired infections. Because of development of antimicrobial resistance carbapenem has remained as last resort of drug for treatment of infections caused by these ...
Satyajeet K. Pawar, Shivaji T. Mohite, Kailash D. Datkhile, Madhavi N. Patil, Satish V. Kakade   +4 more
doaj   +1 more source

OXA-900, a Novel OXA Sub-Family Carbapenemase Identified in Citrobacter freundii, Evades Detection by Commercial Molecular Diagnostics Tests

Microorganisms, 2021
Using whole-genome sequencing and cloning of the target gene, we identified blaOXA-900 carbapenemase, a novel blaOXA belonging to a distant and distinct sub-family of blaOXA-48-like. The plasmid-mediated gene was identified in a C.
Sammy Frenk, Nadya Rakovitsky, Hadas Kon, Reut Rov, Shirin Abramov, Mor Nadia Lurie-Weinberger, David Schwartz, Erica Pinco, Jonathan Lellouche, Yehuda Carmeli   +9 more
doaj   +1 more source

Development of a Novel Real-Time PCR Assay with High-Resolution Melt Analysis To Detect and Differentiate OXA-48-Like β-Lactamases in Carbapenem-Resistant Enterobacteriaceae [PDF]

, 2015
The rapid global spread of carbapenem-resistant Enterobacteriaceae (CRE) poses an urgent threat to public health. More than 250 class D β-lactamases (OXAs) have been described in recent years, with variations in hydrolytic activity for β-lactams.
Humphries, Romney M, Hemarajata, Peera, Yang, Shangxin, Hindler, Janet A   +3 more
core   +1 more source