Trends in carbapenemase-producing Enterobacteriaceae, France, 2012 to 2014. [PDF]
In 2014, a total of 2,976 Enterobacteriaceae isolates with decreased susceptibility to carbapenems were received at the French Associated National Reference Center for Antibiotic Resistance (NRC) and were characterised for their molecular resistance ...
Cuzon, G. +3 more
core +1 more source
WCK 4234, a novel diazabicyclooctane potentiating carbapenems against Enterobacteriaceae, Pseudomonas and Acinetobacter with class A, C and D β-lactamases [PDF]
Background: Several diazabicyclooctanes (DBOs) are under development as inhibitors of Class A and C -lactamases. Inhibition of OXA (Class D) carbapenemases is variable, with those of Acinetobacter spp. remaining notably resistant. We describe a novel DBO,
Anna Vickers +4 more
core +1 more source
Members of Enterobacteriaceae family are responsible for both community and hospital acquired infections. Because of development of antimicrobial resistance carbapenem has remained as last resort of drug for treatment of infections caused by these ...
Satyajeet K. Pawar +4 more
doaj +1 more source
Using whole-genome sequencing and cloning of the target gene, we identified blaOXA-900 carbapenemase, a novel blaOXA belonging to a distant and distinct sub-family of blaOXA-48-like. The plasmid-mediated gene was identified in a C.
Sammy Frenk +9 more
doaj +1 more source
Activity of ceftolozane/tazobactam against surveillance and ‘problem’ Enterobacteriaceae, Pseudomonas aeruginosa and non-fermenters from the British Isles [PDF]
Background: We assessed the activity of ceftolozane/tazobactam against consecutive isolates collected in the BSAC Bacteraemia Surveillance from 2011 to 2015 and against ‘problem’ isolates sent to the UK national reference laboratory from July 2015, when ...
Aiysha Chaudhry +43 more
core +1 more source
NDM-1 and OXA-163 producing Klebsiella pneumoniae isolates in Cairo, Egypt, 2012 [PDF]
Here we describe carbapenem resistance determinants in two Klebsiella pneumoniae isolates recovered from two hospitalised patients in the same intensive care unit of a cancer hospital in Cairo, Egypt.
Abdelaziz, M. O. +4 more
core +1 more source
Genetic and Biochemical Characterization of OXA-519, a Novel OXA-48-Like β-Lactamase. [PDF]
A multidrug-resistantKlebsiella pneumoniae1210 isolate with reduced carbapenem susceptibility revealed the presence of a novel plasmid-encodedblaOXA-48-likegene, namedblaOXA-519. The 60.7-kb plasmid (pOXA-519) was similar to the IncL-OXA-48 prototypical plasmid except for a ca.
Dabos L +8 more
europepmc +5 more sources
Emergence of NDM-1-producing Enterobacteriaceae in China [PDF]
postprin
Cheng, VCC +4 more
core +4 more sources
Carbapenemase-producing Enterobacteriaceae in hospital wastewater:a reservoir that may be unrelated to clinical isolates [star] [PDF]
Summary Background: Carbapenemase-producing Enterobacteriaceae (CPE) are an emerging infection control problem in hospitals worldwide. Identifying carriers can help reduce potential spread and infections.
Cheesbrough, John +8 more
core +1 more source
Epidemiology and control measures of an OXA-48- producing Enterobacteriaceae hospital outbreak [PDF]
Carbapenemase-producing Enterobacteriaceae (CPE) are a significant challenge to healthcare and infection prevention and control teams. In the UK, OXA-48-like carbapenemases are frequently reported.
Carter, Y. +13 more
core +1 more source

