Results 41 to 50 of about 52,257,618 (175)

Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK [PDF]

Journal of Antimicrobial Chemotherapy, 2012
To characterize UK clinical isolates of Enterobacteriaceae producing OXA-48-like carbapenemases and to compare their resistance plasmids.Twenty-six enterobacteria producing OXA-48-like enzymes were studied. These were from 22 diverse hospitals in the UK.
Dimou, Vassiliki, Dhanji, Hiran, Pike, Rachel, Livermore, David M., Woodford, Neil   +4 more
openaire   +3 more sources

Susceptibility of Clinical Enterobacterales Isolates With Common and Rare Carbapenemases to Mecillinam

Frontiers in Microbiology, 2021
Purpose: To investigate the susceptibility of carbapenemase-producing Enterobacterales (CPE) to mecillinam based on the recently updated European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints for uncomplicated Urinary Tract ...
Frieder Fuchs, Aysel Ahmadzada, Lars Plambeck, Thorsten Wille, Axel Hamprecht, Axel Hamprecht, Axel Hamprecht   +6 more
doaj   +1 more source

Emergence of OXA-48-like producing <i>Citrobacter</i> species, Germany, 2011 to 2022. [PDF]

Euro Surveill
Background Carbapenemase-producing Enterobacterales are a public health threat worldwide and OXA-48 is the most prevalent carbapenemase in Germany and western Europe. However, the molecular epidemiology of OXA-48 in species other than Escherichia coli and Klebsiella pneumoniae remains poorly understood.
Sommer J, Reiter H, Sattler J, Cacace E, Eisfeld J, Gatermann S, Hamprecht A, Göttig S.   +7 more
europepmc   +4 more sources

Characterisation of OXA-48-like carbapenemases in Escherichia coli and Klebsiella pneumoniae from North India. [PDF]

3 Biotech, 2023
The oxacillinase-48 (OXA-48)-like carbapenemases are class D β-lactamases and increasingly reported in Enterobacterial species. The detection of these carbapenemases is challenging and little information is available on the epidemiology and plasmid characteristics of OXA-48-like carbapenemase producers.
Singh S, Pathak A, Fatima N, Sahu C, Prasad KN.   +4 more
europepmc   +3 more sources

Detection of OXA-48-like-producing Enterobacterales in Irish recreational water [PDF]

Science of The Total Environment, 2019
The rapid dissemination of carbapenemase-producing Enterobacterales (CPE) is a major public health concern. The role that the aquatic environment plays in this dissemination is underexplored. This study aimed to examine seawater as a reservoir for CPE. Seawater sampling took place at a bathing site throughout the 2017 bathing season.
Mahon, BM, Brehony, C, Cahill, N, McGrath, E, O'Connor, L, Varley, A, Cormican, M, Ryan, S, Hickey, P, Keane, S, Mulligan, M, Ruane, B, Jolley, KA, Maiden, MC, Brisse, S, Morris, D   +15 more
openaire   +2 more sources

Characterization of OXA-48-like carbapenemase producers in Canada, 2011–14 [PDF]

Journal of Antimicrobial Chemotherapy, 2017
Since the first identification of the OXA-48 carbapenemase in 2001, Enterobacteriaceae harbouring OXA-48-like enzymes have been reported globally. Here, we applied WGS to characterize the molecular epidemiology of these bacterial isolates.Enterobacteriaceae non-susceptible to carbapenems isolated from patients between 2011 and 2014 were voluntarily ...
Laura F, Mataseje, David A, Boyd, Jeffrey, Fuller, David, Haldane, Linda, Hoang, Brigitte, Lefebvre, Roberto G, Melano, Susan, Poutanen, Paul, Van Caeseele, Michael R, Mulvey   +9 more
openaire   +2 more sources

Rapid Screening for Carbapenem Resistant Organisms: Current Results and Future Approaches [PDF]

Journal of Clinical and Diagnostic Research, 2015
Carbapenem producing Enterobacteriaceae (CPE) is a major public health threat. A total of 120 carbapenem resistant E.coli (n=32) and K.pneumoniae (n=88) from blood stream infections were screened for the presence of carbapenem resistant genes KPC, NDM ...
Shalini Anandan, Sunganya Damodaran, Radha Gopi, Yamuna Devi Bakthavatchalam, Balaji Veeraraghavan   +4 more
doaj   +1 more source

Enterobacteriaceae producing OXA-48-like carbapenemases in Poland, 2013–January 2017 [PDF]

Journal of Antimicrobial Chemotherapy, 2017
To analyse OXA-48 (OXA-48/181)-type carbapenemase-producing Enterobacteriaceae reported in Poland from 2013 until January 2017.Bacterial isolates were typed by PFGE and MLST. Genes coding for OXA-48/181 types and other β-lactamases were amplified and sequenced. Mobile elements with blaOXA-48/181-like genes were PCR mapped.
Izdebski, R., Baraniak, A., Zabicka, D., Machulska, M., Urbanowicz, P., Fiett, J., Literacka, E., Bojarska, K., Kozińska, A., Bartłomiej Zieniuk, Hryniewicz, W., Gniadkowski, M., Chrystyniuk, P., Durnaś, B., Kȩdzierska, J., Mól, A., Swoboda-Kopeć, E., Wróblewska, M., Tomanek, E., Wcisło-Wach, B.   +19 more
openaire   +2 more sources

Comparison of ceftazidime-avibactam susceptibility testing methods against OXA-48-like carrying Klebsiella blood stream isolates

, 2022
Ceftazidime-avibactam exhibits good in vitro activity against carbapenem resistant Klebsiella carrying OXA-48-like enzymes. We tested two hundred unique carbapenem resistant Klebsiella blood stream isolates (71% with single OXA-48-like carbapenemases ...
Yagci, Serap, Arabaci, Çiğdem, Azap, Özlem, ÇINAR, GÜLE, Aydın, Mehtap, Tigen, Elif Tükenmez, Bakir, Veli Oguzalp, TİGEN, ELİF, Özer, Berna, Forde, Brian, Demirkaya, Hamiyet, Keşke, Siran, Dogan, Özlem, ASLAN, ABDULLAH TARIK, Akova, Murat, Menekse, Sirin, Çınar, Güle, Paterson, David L., Gönen, Mehmet, Bakır, Veli Oğuzalp, Aslan, Abdullah Tarık, Yağcı, Serap, İşler, Burcu, Bauer, Michelle J., Aydin, Mehtap, Stewart, Adam, Balkan, İlker İnanc, Kapmaz, Mahir, Saltoğlu, Neşe, Vatansever, Cansel, Tülek, Necla, Ergonul, Önder, Şimşek, Funda, Akalin,Halis, Akalinj, Halis, Demir, Safiye Koculu, Harris, Patrick, Azap, Alpay, Falconer, Caitlin, Hazirolan, Gülşen, Simos, Peter, Can, Fusun   +41 more
core   +2 more sources

Multiscale simulations identify origins of differential carbapenem hydrolysis by the OXA-48 β-lactamase [PDF]

, 2022
OXA-48 β-lactamases are frequently encountered in bacterial infections caused by carbapenem-resistant Gram-negative bacteria. Due to the importance of carbapenems in treatment of healthcare-associated infections, and the increasingly wide dissemination ...
Marc, van der Kamp, Tal, Moshe Weizmann, Adrian, Mulholland, James , Spencer, Viivi, Hirvonen   +4 more
core   +2 more sources