An MLST approach to support tracking of plasmids carrying OXA-48-like carbapenemase. [PDF]
J Antimicrob Chemother, 2019 AbstractObjectivesThe prevalence of infections caused by OXA-48-like carbapenemase-producing organisms in Ireland has increased dramatically since 2011 and is an urgent public health issue. Genome-based high-resolution genotyping was used to analyse clinical isolates submitted to the Irish Carbapenemase-Producing Enterobacteriaceae Reference Laboratory
Brehony C +9 more
europepmc +8 more sources
To Be or Not to Be an OXA-48 Carbapenemase
Microorganisms, 2022 Since the first description of OXA-48, more than forty variants have been recovered from Enterobacterales isolates. Whereas some OXA-48-related enzymes have been reported as conferring similar resistance patterns, namely, the hydrolysis of carbapenems ...
Laura Dabos +5 more
doaj +1 more source
Evaluation of an Immunochromatographic Lateral Flow Assay (OXA-48 K-SeT) for Rapid Detection of OXA-48-Like Carbapenemases in Enterobacteriaceae [PDF]
, 2016 We evaluated an immunochromatographic lateral flow assay for the detection of OXA-48-like carbapenemases (OXA-48 K-SeT) in Enterobacteriaceae (n=82). 100% sensitivity and specificity was observed using bacteria recovered from both solid media and spiked ...
Betts, JW +4 more
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Evaluation of the Blue-Carba test for rapid detection of carbapenemases in gram-negative Bacilli [PDF]
, 2015 The Blue-Carba test (BCT) is a biochemical test for rapid (2 h)detection of carbapenemase production in Gram-negative bacillidirectly from bacterial culture .
Albornoz, Ezequiel Pablo +7 more
core +1 more source
Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study. [PDF]
, 2019 Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST).
Aller, SD +20 more
core +4 more sources
Increasing proportion of carbapenemase-producing Enterobacteriaceae and emergence of a MCR-1 producer through a multicentric study among hospital-based and private laboratories in Belgium from September to November 2015 [PDF]
, 2017 Carbapenemase-producing Enterobacteriaceae (CPE) strains have been increasingly reported in Belgium. We aimed to determine the proportion of CPE among Enterobacteriaceae isolated from hospitalised patients and community outpatients in Belgium in 2015 ...
Bauraing, Caroline +8 more
core +1 more source
Electrostatic interactions define nacubactam potency against OXA-48-like β-lactamases
AbstractCarbapenemases, β-lactamases hydrolysing carbapenem antibiotics, severely challenge treatment of multi-drug resistant bacterial infections. OXA-48 is among the most widely disseminated carbapenemases inEnterobacterales, consequently new treatment options for OXA-48 producers are urgently required.
Hoff JF +9 more
europepmc +2 more sources
Infection and Drug Resistance, 2022 Yicheng Wen,1,* Xiaofang Xie,1,* Ping Xu,2,* Chengcheng Yang,1 Zhichen Zhu,1 Jie Zhu,1 Jingnan Lv,1 Haifang Zhang,1 Liang Chen,3,4 Hong Du1 1Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou ...
Wen Y +9 more
doaj
Emergence of an MDR Klebsiella pneumoniae ST231 producing OXA-232 and RmtF in Switzerland [PDF]
, 2017 The increasing incidence of carbapenem-resistant Klebsiella pneumoniae is a major challenge to public health. Despite the fact that the prevalence of carbapenemases among carbapenem-resistant K.
Bassi, Cécile +5 more
core +1 more source
Evaluation of CHROMagar™mSuperCARBA™ as a Phenotypic Test for Detection of Carbapenemase Producing Organisms [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Carbapenem resistance among Enterobacteriaceae continues to escalate. Carbapenemase encoding genes borne on plasmids leads to wide-spread transmission among Enterobacteriaceae.
Anushree Ulhas Amladi +5 more
doaj +1 more source