Results 21 to 30 of about 1,937 (148)

Connexins and pannexins: from biology towards clinical targets

Swiss Medical Weekly, 2016
Efficient cell communication is a prerequisite for the coordinated function of tissues and organs. In vertebrates, this communication is mediated by a variety of mechanisms, including the exchange of molecules between cells, and between cells and the ...
Paolo Meda, Jacques-Antoine Haefliger
doaj   +2 more sources

Role of astrocytes connexins - pannexins in acute brain injury [PDF]

Neurotherapeutics
Acute brain injuries (ABIs) encompass a broad spectrum of primary injuries such as ischemia, hypoxia, trauma, and hemorrhage that converge into secondary injury where some mechanisms show common determinants.
Juan E. Tichauer, Maximiliano Rovegno
doaj   +2 more sources

Expression and Roles of Pannexins in ATP Release in the Pituitary Gland

, 2011
Pannexins are a newly discovered three-member family of proteins expressed in the brain and peripheral tissues that belong to the superfamily of gap junction proteins.
Stanko S. Stojilkovic, Bjelobaba, Ivana, Tomić, Melanija, Melanija Tomić, Li, Shuo, Marek Kucka, Zonghe Yan, Yan, Zonghe, Ivana Bjelobaba, Kucka, Marek, Stojilković, Stanko S, Shuo Li   +11 more
core   +7 more sources

Connexins and pannexins in liver damage [PDF]

, 2016
Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function these proteins are frequently involved in pathological processes.
Cogliati, Bruno, Willebrords, Joost, Maes, Michaël, Vinken, Mathieu, Veloso Alves Pereira, Isabel, Crespo Yanguas, Sara, da Silva, Tereza Cristina, Zaidan Dagli, Maria Lucia   +7 more
core   +1 more source

Role of connexins and pannexins in cardiovascular physiology [PDF]

, 2021
Connexins and pannexins form connexons, pannexons and membrane channels, which are critically involved in many aspects of cardiovascular physiology.
Duffy, Heather, Kwak, Brenda, Meens, Merlijn   +2 more
core  

Functional implications of calcium permeability of the channel formed by pannexin 1. [PDF]

, 2006
Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca(2+)-permeable gap ...
Ivanov, Dmitry, V, Panchin, YV, Vanden Abeele, F, Fabien Vanden Abeele, Panchin, Yuri V, Gordienko, D, Yuri V. Panchin, Baranova, AV, Skryma, R, Baranova, Ancha, V, Skryma, Roman, Gordienko, Dmitri, Gabriel Bidaux, Beck, Benjamin, Ivanov, DV, Prevarskaya, N, Ancha V. Baranova, Baranova, Ancha V, Natalia Prevarskaya, Benjamin Beck, Ivanov, Dmitry V, Panchin, Yuri, Ivanov, Dimitri, Prevarskaya, Natalia, Vanden Abeele, Fabien, Bidaux, G, Bidaux, Gabriel, Dmitry V. Ivanov, Beck, B, Panchin, Yuri, V, Roman Skryma, Dmitri Gordienko   +31 more
core   +1 more source

Prenatal nicotine exposure enhances Cx43 and Panx1 unopposed channel activity in brain cells of adult offspring mice fed a high-fat/cholesterol diet

Frontiers in Cellular Neuroscience, 2014
Nicotine, the most important neuroteratogen of tobacco smoke, can reproduce brain and cognitive disturbances per se when administered prenatally. However, it is still unknown if paracrine signaling among brain cells participates in prenatal nicotine ...
Juan Andrés Orellana, Dolores eBusso, Gigliola eRamirez, Marlys eCampos, Attilio eRigotti, Jaime eEugenin, Rommy eVon Bernhardi   +6 more
doaj   +1 more source

Pannexins and Connexins: Their Relevance for Oocyte Developmental Competence

, 2021
The oocyte is the major determinant of embryo developmental competence in all mammalian species. Although fundamental advances have been generated in the field of reproductive medicine and assisted reproductive technologies in the past three decades ...
Mariusz T. Skowronski, Paweł Kordowitzki, Agnieszka Skowronska, Marta Wasielak-Politowska, Gabriela Sokołowska   +4 more
core   +1 more source

Control of the neurovascular coupling by nitric oxide-dependent regulation of astrocytic Ca2+ signaling

Frontiers in Cellular Neuroscience, 2015
Neuronal activity must be tightly coordinated with blood flow to keep proper brain function, which is achieved by a mechanism known as neurovascular coupling. Then, an increase in synaptic activity leads to a dilation of local parenchymal arterioles that
Manuel Francisco Muñoz, Mariela ePuebla, Xavier eFigueroa   +2 more
doaj   +1 more source

Lymphatic Connexins and Pannexins in Health and Disease

, 2021
This review highlights current knowledge on the expression and function of connexins and pannexins, transmembrane channel proteins that play an important role in intercellular communication, in both the developing and mature lymphatic vasculature.
Avigail Ehrlich, Aurélie Hautefort, Molica, Filippo, Kwak, Brenda, Brenda R. Kwak, Hautefort, Aurélie, Filippo Molica, Ehrlich, Avigail   +7 more
core   +1 more source