Results 31 to 40 of about 1,937 (148)
Restraint stress increases hemichannel activity in hippocampal glial cells and neurons
Frontiers in Cellular Neuroscience, 2015 Stress affects brain areas involved in learning and emotional responses, which may contribute in the development of cognitive deficits associated with major depression.
Juan Andrés Orellana +6 more
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Communications Biology, 2022 The Panx1a and Panx1b (pannexin) ATP release channels exhibit pro- and anti-convulsant effects, respectively, in a zebrafish model, providing further insight into the role of pannexins in seizure development.
Paige Whyte-Fagundes +6 more
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Frontiers in Cellular Neuroscience, 2021 Electrical synaptic transmission is an essential form of interneuronal communication which is mediated by gap junctions that permit ion flow. Three gene families (connexins, innexins, and pannexins) have evolved to form gap junctional channels.
Qiqian Wang, Shenquan Liu
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Role of connexins and pannexins during ontogeny, regeneration, and pathologies of bone [PDF]
, 2016 International audienceElectron micrographs revealed the presence of gap junctions in osteoblastic cells over 40 years ago. These intercellular channels formed from connexins are present in bone forming osteoblasts, bone resorbing osteoclasts, and ...
Amédée, Joëlle +6 more
core +1 more source
The Role of Pannexin Hemichannels in Inflammation and Regeneration
Frontiers in Physiology, 2014 Tissue injury involves coordinated systemic responses including inflammatory response, targeted cell migration, cell-cell communication, stem cell activation and proliferation, and tissue regeneration.
Helen P. Makarenkova +2 more
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Frontiers in Cellular Neuroscience, 2019 A variety of glial cell functions are supported by connexin and pannexin proteins. These functions include the modulation of synaptic gain, the control of excitability through regulation of the ion and neurotransmitter composition of the extracellular ...
Lucila Brocardo +3 more
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Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function
Frontiers in Molecular Neuroscience, 2017 Panx1 forms plasma membrane channels in brain and several other organs, including the inner ear. Biophysical properties, activation mechanisms and modulators of Panx1 channels have been characterized in detail, however the impact of Panx1 on auditory ...
Veronica Zorzi +23 more
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Pannexins and gap junction protein diversity
, 2008 Gap junctions (GJs) are composed of proteins that form a channel connecting the cytoplasm of adjacent cells. Connexins were initially considered to be the only proteins capable of GJ formation. Another family of GJ proteins (innexins) were first found in
Shestopalov, V I, Panchin, Y
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Anti-parasitic drugs modulate the non-selective channels formed by connexins or pannexins
, 2021 The proteins connexins, innexins, and pannexins are the subunits of non-selective channels present in the cell membrane in vertebrates (connexins and pannexins) and invertebrates (innexins).
Gutiérrez, Camila +6 more
core +1 more source
Promises and pitfalls of a Pannexin1 transgenic mouse line.
Frontiers in Pharmacology, 2013 Gene targeting strategies have become a powerful technology for elucidating mammalian gene function. The recently generated knockout (KO)-first strategy produces a knockout at the RNA processing level and also allows for the generation of conditional KO ...
Regina eHanstein +7 more
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