An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
MEMBANGUNKNOWLEDGE SHARINGBEHAVIOR: MENINGKATKANPERILAKU KERJA INOVATIFBERBASIS PERSON-ORGANIZATION FIT DAN PERSON-JOB FIT [PDF]
, 2019 Tujuan utama penelitian ini adalah untuk menguji pengaruh person-organization fit, person-job fit, dan knowledge sharing behaviorterhadap perilaku kerja inovatif.
SUNARSO, SUNARSO
core +1 more source
Happiness at Work: Organizational Values and Person-Organization Fit Impact
Paidéia (Ribeirão Preto), 2015 Despite the large quantity of research on person-organization (PO) fit, there is a lack of empirical research using axiological theories applicable to the value structure at the individual and organizational levels.
Juliana Moraes de Sousa +1 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Person Organization Fit dan Kinerja Karyawan Milenial [PDF]
Penelitian ini bertujuan untuk mengetahui hubungan antara person organization fit dengan kinerja karyawan milenial. Dalam penelitian ini menggunakan teknik quota sampling dan purposive sampling.
Novianita, Shintia
core +1 more source
The Impact of Career Adaptability on Career Plateau: The Mediating Role of Person-Job Fit and Person-Organization Fit [PDF]
فرایند مدیریت و توسعه, 2019 This research has been conducted to examine the impact of career adaptability on career plateau by explaining the mediating role of person-job fit and person-organization fit. In terms of purpose, the study is applied and it was conducted by descriptive /
Hojjat Taheri Goodarzi, Neda Norouzi
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
How Nurses' Person-Organization Fit Influences Organizational Loyalty. [PDF]
Risk Manag Healthc Policy, 2023 Sun M, Alam F, Ma C.
europepmc +1 more source