Results 81 to 90 of about 3,425 (209)
The Prorenin and (Pro)renin Receptor: New Players in the Brain Renin-Angiotensin System?
International Journal of Hypertension, 2012 It is well known that the brain renin-angiotensin (RAS) system plays an essential role in the development of hypertension, mainly through the modulation of autonomic activities and vasopressin release. However, how the brain synthesizes angiotensin (Ang)
Wencheng Li +3 more
doaj +1 more source
The effect of 30 min of supine rest on plasma renin concentrations in paediatric patients
Acta Paediatrica, Volume 113, Issue 11, Page 2473-2478, November 2024.Abstract Aim The aim of this study is to interpret plasma renin concentrations (PRCs) correctly in a clinical setting, it is essential to understand to what extent physical activity influences the concentration. Reference values for different postural positions exist for adults, but data for children are sparse.
D. F. Al‐Zoubaidi +3 more
wiley +1 more source
Activation of prorenin by proteases from polymorphonuclear leukocytes
, 1980 Inactive renin (prorenin) can be activated by certain proteases in human blood, of which a possible source in vivo is polymorphonuclear leukocytes (PMNs).
D.W. Cox +2 more
core +1 more source
Renin as a target of direct pharmacological block in arterial hypertension
Терапевтический архив, 2009 Renin is a basic component of renin-angiotensin-aldosteron system which contributes much to the activity of this system. Renin and its precursor prorenin can interact with prorenin receptors thus inducing hypertrophy and fibrogenesis in target tissues ...
Nikolay Alekseevich Mukhin +3 more
doaj
The Pathological Role of Pro(Renin) Receptor in Renal Inflammation
Journal of Experimental Pharmacology, 2021 Syed S Quadri,1 Caleb Cooper,2 Dawood Ghaffar,1 Hitesh Vaishnav,1 Ludmila Nahar3 1DeBusk College of Osteopathic Medicine, Lincoln Memorial University, Knoxville, TN, USA; 2DeBusk College of Osteopathic Medicine, Lincoln Memorial University, Harrogate, TN,
Quadri SS +4 more
doaj
Autophagy and the (pro)renin receptor
Frontiers in Endocrinology, 2013 The (pro)renin receptor (PRR) is a newly reported member of the renin-angiotensin system (RAS); a hormonal cascade responsible for regulating blood pressure.
Katrina Jean Binger, Dominik N Muller
doaj +1 more source
Cathepsin B in cardiovascular disease: Underlying mechanisms and therapeutic strategies
Journal of Cellular and Molecular Medicine, Volume 28, Issue 17, September 2024.Abstract Cathepsin B (CTSB) is a member of the cysteine protease family, primarily responsible for degrading unnecessary organelles and proteins within the acidic milieu of lysosomes to facilitate recycling. Recent research has revealed that CTSB plays a multifaceted role beyond its function as a proteolytic enzyme in lysosomes.
Zhulan Cai, Shunyao Xu, Chen Liu
wiley +1 more source
International Journal of Endocrinology, 2015 The intrauterine renin angiotensin system (RAS) is implicated in placentation and labour onset. Here we investigate whether promoter methylation of RAS genes changes with gestation or labour and if it affects gene expression.
Shane D. Sykes +5 more
doaj +1 more source
Lipids in Health and Disease, 2018 Background Hypertension may result from high-fat (HF) diet induced-obesity and overexposure to glucocorticoids in utero. Recent studies demonstrated the potent contribution of adipose tissue’s renin-angiotensin system (RAS) to systemic RAS, which plays a
Hong-Ren Yu +10 more
doaj +1 more source
Wnt signaling in cell adhesion, development, and colon cancer
IUBMB Life, Volume 76, Issue 7, Page 383-396, July 2024.Abstract Wnt signaling is essential for embryonic development, influencing processes such as axis formation, cell proliferation and differentiation, cell fate decisions, and axon guidance. It also plays a role in maintaining tissue homeostasis in adult organisms.
Nydia Tejeda‐Muñoz, Kuo‐Ching Mei
wiley +1 more source