Results 41 to 50 of about 746,971 (308)
Regulation of Neuronal Protein Trafficking and Translocation by SUMOylation
Biomolecules, 2012 Post-translational modifications of proteins are essential for cell function. Covalent modification by SUMO (small ubiquitin-like modifier) plays a role in multiple cell processes, including transcriptional regulation, DNA damage repair, protein ...
Jeremy M. Henley +2 more
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Doa10 is a membrane protein retrotranslocase in ER-associated protein degradation
eLife, 2020 In endoplasmic reticulum-associated protein degradation (ERAD), membrane proteins are ubiquitinated, extracted from the membrane, and degraded by the proteasome. The cytosolic ATPase Cdc48 drives extraction by pulling on polyubiquitinated substrates. How
Claudia C Schmidt +2 more
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Structure of a translocation signal domain mediating conjugative transfer by Type IV secretion systems [PDF]
, 2013 Relaxases are proteins responsible for the transfer of plasmid and chromosomal DNA from one bacterium to another during conjugation. They covalently react with a specific phosphodiester bond within DNA origin of transfer sequences, forming a nucleo ...
Gruber, C.J. +7 more
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Frontiers in Microbiology, 2022 Most motile bacteria utilize the flagellar type III secretion system (fT3SS) to construct the flagellum, which is a supramolecular motility machine consisting of basal body rings and an axial structure.
Tohru Minamino +4 more
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Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation [PDF]
, 2007 During cotranslational protein targeting, two guanosine triphosphatase (GTPase) in the signal recognition particle (SRP) and its receptor (SR) form a unique complex in which hydrolyses of both guanosine triphosphates (GTP) are activated in a shared ...
Chandrasekar, Sowmya +2 more
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Understanding protein import in diverse non-green plastids
Frontiers in Genetics, 2023 The spectacular diversity of plastids in non-green organs such as flowers, fruits, roots, tubers, and senescing leaves represents a Universe of metabolic processes in higher plants that remain to be completely characterized.
Ryan Christian +5 more
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Genetic Analysis of Protein Translocation. [PDF]
Protein J, 2019 Cells in all domains of life must translocate newly synthesized proteins both across membranes and into membranes. In eukaryotes, proteins are translocated into the lumen of the ER or the ER membrane. In prokaryotes, proteins are translocated into the cytoplasmic membrane or through the membrane into the periplasm for Gram-negative bacteria or the ...
Silhavy TJ, Mitchell AM.
europepmc +4 more sources
mBio, 2019 Helicobacter pylori colonizes about half of humans worldwide, and its presence in the gastric mucosa is associated with an increased risk of gastric adenocarcinoma, gastric lymphoma, and peptic ulcer disease. H.
Bo Hu +7 more
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Protein translocation machineries of peroxisomes [PDF]
FEBS Letters, 2001 Targeting of peroxisomal matrix and membrane proteins is performed by distinct transport machineries and requires the concerted action of at least 23 peroxins. Cargo recognition takes place in the cytosol and the multiple binding sites for peroxisomal signal sequence receptors at the peroxisomal membrane reflect the existence of an import cascade where
Holroyd, Claudia, Erdmann, Ralf
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Translocator protein mediates olfactory repulsion [PDF]
The FASEB Journal, 2019 Abstract Translocator protein (TSPO, 18kDa), which was previously known as a peripheral‐type benzodiazepine receptor, is associated with psychiatric disorders and acts as a neuroimaging biomarker. However, its function and mechanism in modulating behaviors are less well‐known.
Zongyuan, Ma, Xiaojiao, Guo, Jipeng, Liu
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