Results 21 to 30 of about 876,735 (231)

Clinical consequences of relative biological effectiveness variations in proton radiotherapy of the prostate, brain and liver [PDF]

, 2013
Proton relative biological effectiveness (RBE) is known to depend on the (alpha/beta)(x) of irradiated tissues, with evidence of similar to 60% variation over (alpha/beta)(x) values from 1-10 Gy.
Carabe, Alejandro, Espana Palomares, Samuel, Grassberger, Clemens, Paganetti, Harald   +3 more
core   +1 more source

Evaluation of the Response of HNSCC Cell Lines to γ-Rays and 12C Ions: Can Radioresistant Tumors Be Identified and Selected for 12C Ion Radiotherapy?

Frontiers in Oncology, 2022
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Thirty percent of patients will experience locoregional recurrence for which median survival is less than 1 year.
Lianghao Ding, Brock J. Sishc, Elizabeth Polsdofer, John S. Yordy, Angelica Facoetti, Mario Ciocca, Debabrata Saha, Arnold Pompos, Anthony J. Davis, Michael D. Story   +9 more
doaj   +1 more source

Rapid RBE-Weighted Proton Radiation Dosimetry Risk Assessment [PDF]

, 2016
Proton therapy dose is affected by relative biological effectiveness differently than X-ray therapies. The current clinically accepted weighting factor is 1.1 at all positions along the depth–dose profile.
Buchsbaum, Jeffrey C., Klein, Susan B., Qutub, Mohammad A. Z.   +2 more
core   +1 more source

Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis (ORN) in Head and Neck Cancer Patients Treated With Pencil-Beam-Scanning Proton Therapy (PBSPT): A Retrospective, Case-Matched Cohort Study

Frontiers in Oncology, 2022
PurposeTo retrospectively investigate empirical relative biological effectiveness (RBE) for mandible osteoradionecrosis (ORN) in head and neck (H&N) cancer patients treated with pencil-beam-scanning proton therapy (PBSPT).MethodsWe included 1,266 H ...
Yunze Yang, Olivia M. Muller, Satomi Shiraishi, Matthew Harper, Adam C. Amundson, William W. Wong, Lisa A. McGee, Jean-Claude M. Rwigema, Steven E. Schild, Martin Bues, Mirek Fatyga, Justin D. Anderson, Samir H. Patel, Robert L. Foote, Wei Liu   +14 more
doaj   +1 more source

Radiobiological studies with monoenergetic neutrons [PDF]

, 1973
The Radiological Research Accelerator Facility (RARAF) has the capability of producing essentially monoenergetic neutron beams, ranging in energy from 16.4 MeV down to 220 keV.
Goodman, L. J., Hall, E. J., Kellerer, Albrecht M., Marino, S., Rossi, H. H.   +4 more
core   +1 more source

Genomic stability in response to high versus low linear energy transfer radiation in Arabidopsis thaliana. [PDF]

, 2014
Low linear energy transfer (LET) gamma rays and high LET HZE (high atomic weight, high energy) particles act as powerful mutagens in both plants and animals.
Britt, Anne B, Conklin, Phillip A, Friesner, Joanna D, Huefner, Neil D, Yoshiyama, Kaoru   +4 more
core   +1 more source

Absence of a dose-rate effect in the transformation of C3H 10T1/2 cells by α-particles [PDF]

, 1987
The findings of Hill et al. (1984) on the greatly enhanced transformation frequencies at very low dose rates of fission neutrons induced us to perform an analogous study with -particles at comparable dose rates. Transformation frequencies were determined
Balcer-Kubiczek E.K., Barendsen G.W, Barendsen G.W., Borek C., Burch P.R.J., Elkind M.M., Hall E.J., Han A., Han A., Hill C.K., Hill C.K., Hill C.K., Lloyd E.L., Miller R.C., Miller R.C., Reznikoff C., Robertson J.B., Roos H., Rossi H.H., Terzaghi M., Yang T.   +20 more
core   +1 more source

Relative Biological Effectiveness (RBE) of 131I Radiation Relative to 60Co Gamma Rays [PDF]

Cell Journal, 2013
Objective: To assess relative biological effectiveness (RBE) of 131I radiation relative to 60Co gamma rays in glioblastoma spheroid cells.Materials and Methods: In this experimental study, glioblastoma spheroid cells were exposed to 131I radiation and ...
Seyed Rabie Mahdavi, Ali Mahmoud Pashazadeh, Ali Neshasteh-Riz   +2 more
doaj  

Biophysical modeling and experimental validation of relative biological effectiveness (RBE) for 4He ion beam therapy

Radiation Oncology, 2019
Background Helium (4He) ion beam therapy provides favorable biophysical characteristics compared to currently administered particle therapies, i.e., reduced lateral scattering and enhanced biological damage to deep-seated tumors like heavier ions, while ...
Stewart Mein, Ivana Dokic, Carmen Klein, Thomas Tessonnier, Till Tobias Böhlen, Guiseppe Magro, Julia Bauer, Alfredo Ferrari, Katia Parodi, Thomas Haberer, Jürgen Debus, Amir Abdollahi, Andrea Mairani   +12 more
doaj   +1 more source

Estimating the Relative Biological Effectiveness of Auger Electron Emitter 123I in Human Lymphocytes

Frontiers in Physics, 2020
Auger electron emitters are considered to be a promising strategy for targeted radionuclide therapy of metastatic diseases, given their high linear energy transfer (LET) and short range in tissue which could potentially limit normal tissue toxicity ...
Hein Fourie, Shankari Nair, Xanthene Miles, Daniel Rossouw, Philip Beukes, Richard T. Newman, Jan Rijn Zeevaart, Charlot Vandevoorde, Jacobus Slabbert   +8 more
doaj   +1 more source