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Omega-3 and Sports: Focus on Inflammation [PDF]

Life
Inflammation is expected in sports, especially when practiced at a high level. The human body is pushed toward its limit, and this is perceived as a “stressogenic agent”.
Roberto Cannataro, Diana Marisol Abrego-Guandique, Natascia Straface, Erika Cione   +3 more
doaj   +2 more sources

Role of Resolvins in Inflammatory and Neuropathic Pain

Pharmaceuticals, 2023
Chronic pain is an unpleasant experience associated with actual or potential tissue damage. Inflammatory pain alerts the body to inflammation and promotes healing; however, unresolved inflammation can lead to chronic pain.
Jaeik Park, Jueun Roh, Jingying Pan, Yong Ho Kim, Chul-Kyu Park, Youn Yi Jo   +5 more
doaj   +1 more source

Immunomodulation of periodontitis with SPMs

Frontiers in Oral Health, 2023
Inflammation is a critical component in the pathophysiology of numerous disease processes, with most therapeutic modalities focusing on its inhibition in order to achieve treatment outcomes.
Vaibhav Sahni, Thomas E. Van Dyke, Thomas E. Van Dyke   +2 more
doaj   +1 more source

A combination treatment of low-dose dexamethasone and aspirin-triggered resolvin D1 reduces Sjögren syndrome–like features in a mouse modelWhy Is This Important?

JADA Foundational Science, 2023
Background: Sjögren syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration and diminished secretory function of the salivary glands. Dexamethasone (DEX) resolves dry mouth and lymphocytic infiltration; however, this treatment is
Harim Tavares dos Santos, DDS, PhD, Frank Maslow, BS, Kihoon Nam, PhD, Bryan Trump, DDS, Gary A. Weisman, PhD, Olga J. Baker, DDS, PhD   +5 more
doaj   +1 more source

The Impact of the Ca²⁺-Independent Phospholipase A₂β (iPLA₂β) on Immune Cells

Biomolecules, 2021
The Ca2+-independent phospholipase A2β (iPLA2β) is a member of the PLA2 family that has been proposed to have roles in multiple biological processes including membrane remodeling, cell proliferation, bone formation, male fertility, cell death, and ...
Tayleur D. White, Abdulaziz Almutairi, Ying Gai Tusing, Xiaoyong Lei, Sasanka Ramanadham   +4 more
doaj   +1 more source

Resolvins, Protectins, and Maresins: DHA-Derived Specialized Pro-Resolving Mediators, Biosynthetic Pathways, Synthetic Approaches, and Their Role in Inflammation

Molecules, 2022
Marine organisms are an important source of natural products with unique and diverse chemical structures that may hold the key for the development of novel drugs.
Inês Ferreira, Filipa Falcato, Narcisa Bandarra, Amélia P. Rauter   +3 more
doaj   +1 more source

Obesity-Driven Deficiencies of Specialized Pro-resolving Mediators May Drive Adverse Outcomes During SARS-CoV-2 Infection

Frontiers in Immunology, 2020
Obesity is a major independent risk factor for increased morbidity and mortality upon infection with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), which is responsible for the current coronavirus disease pandemic (COVID-19).
Anandita Pal, Kymberly M. Gowdy, Kenneth J. Oestreich, Melinda Beck, Saame Raza Shaikh   +4 more
doaj   +1 more source

Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins

Mediators of Inflammation, 2020
Acute inflammation has been described as a reactive dynamic process, promoted by the secretion of proinflammatory mediators, including lipid molecules like leukotrienes and prostaglandins, and counterbalanced by proresolving mediators including omega-3 ...
Sajad Chamani, Vanessa Bianconi, Aida Tasbandi, Matteo Pirro, George E. Barreto, Tannaz Jamialahmadi, Amirhossein Sahebkar   +6 more
doaj   +1 more source

Specialized Pro-Resolving Mediators in Neuroinflammation: Overview of Studies and Perspectives of Clinical Applications

Molecules, 2022
Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in the inflammation environment, preventing an overreaction of the organism and ...
Mariarosaria Valente, Marta Dentoni, Fabrizio Bellizzi, Fedra Kuris, Gian Luigi Gigli   +4 more
doaj   +1 more source

The Role of Endogenous Eicosapentaenoic Acid and Docosahexaenoic Acid-Derived Resolvins in Systemic Sclerosis

Frontiers in Immunology, 2020
Resolvins, the member of specialized pro-resolving mediators, are produced from omega-3 polyunsaturated fatty acids as a response to an acute inflammatory process in that termination and resolution of inflammation.
Aslıhan Avanoǧlu Güler, Aslıhan Avanoǧlu Güler, Francesca Wanda Rossi, Silvia Bellando-Randone, Nella Prevete, Abdurrahman Tufan, Mirko Manetti, Amato de Paulis, Marco Matucci-Cerinic   +8 more
doaj   +1 more source