Results 31 to 40 of about 11,193 (162)

Resolution of inflammation in obesity-induced liver disease [PDF]

, 2012
Low-grade inflammation in adipose tissue is recognized as a critical event in the development of obesity-related co-morbidities. This chronic inflammation is powerfully augmented through the infiltration of macrophages, which together with adipocytes ...
Ana González-Périz, Bibiana Rius, Cristina López-Vicario, Esther Titos, Eva Morán-Salvador, Joan Clária, Verónica García-Alonso   +6 more
core   +1 more source

Intake and metabolism of omega-3 and omega-6 polyunsaturated fatty acids: nutritional implications for cardiometabolic diseases [PDF]

, 2020
Prospective observational studies support the use of long-chain omega-3 polyunsaturated fatty acids (PUFAs) in the primary prevention of atherosclerotic cardiovascular disease; however, randomised controlled trials, have often reported neutral findings ...
Abdelhamid, Abdelhamid, Al-Hilal, Allayee, Armstrong, Aung, Baylin, Bhatt, Bjermo, Bosch, Bowman, Brown, Burdge, Burr, Cannon, Chavez, Cho, Chowdhury, Colazzo, Contreras, Cormier, Das, Dayton, de Toro-Martin, Demetz, Dorris, Draisma, Dumont, Dumont, Dupuis, Dwyer, Farvid, Fezeu, Floegel, Floegel, Forouhi, Frantz, Fretts, Fumagalli, Gabbs, Gammelmark, Gammelmark, Gillingham, Gol, Gromovsky, Guan, Hamley, Harris, Harris, Harris, Heemskerk, Hellstrand, Hilvo, Hooper, Hu, Illig, Imamura, Innes, Jakobsen, Jamieson, Johnson, Juan, Jäger, Jäger, Keaney, Kemp, Kromhout, Kröger, Kröger, Lankinen, Lemaitre, Leren, Li, Ligthart, Liu, Lu, Mahajan, Maki, Manson, Marklund, Marklund, McManus, Micha, Miettinen, Moltó-Puigmartí, Monk, Monteiro, Mozaffarian, Mozaffarian, Mozaffarian, Nelson, Nicholls, O'Neill, Pan, Piepoli, Powell, Ramsden, Ramsden, Ramsden, Ratnayake, Rimm, Risérus, Rizos, Roncaglioni, Rosqvist, Ross, Sarwar, Serhan, Simopoulos, Sioen, Siscovick, Skeaff, Skulas-Ray, Smith, Standl, Stephensen, Stoffel, Sudmant, Sun, Takkunen, Trumbo, Turpeinen, Wang, Wang, Wei, White, Willer, Woodhill, Wu, Wu, Wu, Xue, Yamagishi, Ye, Yokoyama, Yuan, Zhang   +136 more
core   +1 more source

The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections

Frontiers in Immunology, 2020
G-protein-coupled receptor 40 (GPR40) is known to play a role in the regulation of fatty acids, insulin secretion, and inflammation. However, the function of this receptor in human neutrophils, one of the first leukocytes to arrive at the site of ...
Patricia R. Souza, Mary E. Walker, Nicolas J. Goulding, Jesmond Dalli, Jesmond Dalli, Mauro Perretti, Mauro Perretti, Lucy V. Norling, Lucy V. Norling   +8 more
doaj   +1 more source

Infection, Inflammation, and Immunity in Sepsis

Biomolecules, 2023
Sepsis is triggered by microbial infection, injury, or even major surgery. Both innate and adaptive immune systems are involved in its pathogenesis. Cytoplasmic presence of DNA or RNA of the invading organisms or damaged nuclear material (in the form of ...
Undurti N. Das
doaj   +1 more source

Infection Regulates Pro-Resolving Mediators that Lower Antibiotic Requirements [PDF]

, 2012
Underlying mechanisms for how bacterial infections contribute to active resolution of acute inflammation are unknown. Here, we performed exudate leukocyte trafficking and mediator-metabololipidomics of murine peritoneal Escherichia coli (E.
Bäckhed, Fredrik, Chiang, Nan, Fredman, Gabrielle, Oh, Sungwhan, Schmidt, Birgitta A R, Serhan, Charles Nicholas, Vickery, Thad   +6 more
core   +1 more source

Targeting the D-series resolvin receptor system for the treatment of osteoarthritic pain [PDF]

, 2016
Objective: Pain is a major symptom of osteoarthritis (OA); current analgesics either do not offer adequate pain relief or are associated with serious side effects.
Ashraf, Sadaf, Barrett, David A., Bennett, Andrew J., Burston, James J., Chapman, Victoria, Huang, Junting, Li, Li, Mapp, Paul I., Pousinis, Petros, Ravipati, Srinivasarao, Scammell, Brigitte E.   +10 more
core   +4 more sources

Restoration of Proresolution Pathway with Exogenous Resolvin D1 Prevents Sevoflurane-Induced Cognitive Decline by Attenuating Neuroinflammation in the Hippocampus in Rats with Type 2 Diabetes Mellitus

Frontiers in Pharmacology, 2021
Sevoflurane (SEV), a commonly used volatile anesthetic, has been shown to cause cognitive decline in diabetic rats by aggregating neuroinflammation in the hippocampus, but the underlying mechanisms are unknown.
Qingmei Sun, Hongdan Yan, Falong Chen, Fen Jiang, Wenjuan Chen, Dongliang Li, Yongmin Guo   +6 more
doaj   +1 more source

Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

Journal of Lipid Research, 2013
Placental inflammation is associated with several pregnancy disorders. Inflammation is limited by anti-inflammatory and proresolving mechanisms, the latter partly mediated by resolvins and protectins derived from omega-3 polyunsaturated fatty acids (n ...
Megan L. Jones, Peter J. Mark, Jeffrey A. Keelan, Anne Barden, Emilie Mas, Trevor A. Mori, Brendan J. Waddell   +6 more
doaj   +1 more source

Role of Resolvins in the Inflammatory Resolution of Neurological Diseases

Frontiers in Pharmacology, 2020
The occurrence of neurological diseases including neurodegenerative disorders, neuroimmune diseases, and cerebrovascular disorders is closely related to neuroinflammation. Inflammation is a response against infection or injury. Genetic abnormalities, the
Chunrong Li, Xiujuan Wu, Shan Liu, Donghui Shen, Jie Zhu, Jie Zhu, Kangding Liu   +6 more
doaj   +1 more source

Can essential fatty acids reduce the burden of disease(s)? [PDF]

, 2008
Coronary heart disease, stroke, diabetes mellitus, hypertension, cancer, depression schizophrenia, Alzheimer's disease, and collagen vascular diseases are low-grade systemic inflammatory conditions that are a severe burden on health care resources ...
Undurti N Das
core   +2 more sources