Results 41 to 50 of about 11,193 (162)

Is Lipid Metabolism of Value in Cancer Research and Treatment? Part II: Role of Specialized Pro-Resolving Mediators in Inflammation, Infections, and Cancer

Metabolites
Acute inflammation is the body’s first defense in response to pathogens or injury that is partially governed by a novel genus of endogenous lipid mediators that orchestrate the resolution of inflammation, coined specialized pro-resolving mediators (SPMs).
Muhammad Usman Babar, Ala F. Nassar, Xinxin Nie, Tianxiang Zhang, Jianwei He, Jacky Yeung, Paul Norris, Hideki Ogura, Anne Muldoon, Lieping Chen, Stephania Libreros   +10 more
doaj   +1 more source

Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair [PDF]

, 2017
High-fat diet-induced obesity is a major risk factor for osteoarthritis (OA) and diminished wound healing. The objective of this study was to determine the associations among serum and synovial fluid lipid levels with OA, synovitis, adipokine levels, and
Guilak, Farshid, Kimmerling, Kelly A, Little, Dianne, Wu, Chia-Lung   +3 more
core   +2 more sources

Inflammatory and Pro-resolving Lipids in Trypanosomatid Infections: A Key to Understanding Parasite Control

Frontiers in Microbiology, 2018
Pathogenic trypanosomatids (Trypanosoma cruzi, Trypanosoma brucei, and Leishmania spp.) are protozoan parasites that cause neglected diseases affecting millions of people in Africa, Asia, and the Americas.
Rodrigo A. López-Muñoz, Alfredo Molina-Berríos, Carolina Campos-Estrada, Carolina Campos-Estrada, Patricio Abarca-Sanhueza, Luis Urrutia-Llancaqueo, Miguel Peña-Espinoza, Juan D. Maya   +7 more
doaj   +1 more source

Comparison of effectiveness of low-dose aspirin versus omega-3 fatty acids as adjuvants to nonsurgical periodontal therapy in Type II diabetic patients with chronic periodontitis

Journal of Indian Society of Periodontology, 2019
Context: Periodontitis and diabetes are universally prevalent diseases which are interlinked with each other. Inflammatory products released both by the microorganisms, and the host plays a pivotal role in causing both the diseases.
Prathyusha Rampally, Rekha Rani Koduganti, Sastri Nadiminty Ganapathi, Veerendranath Reddy Panthula, Prasanna Jammula Surya   +4 more
doaj   +1 more source

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis [PDF]

, 2017
National Institutes of Health grants GM-38765 and P50-DE016191 (C.N.S.), Welcome Trust Programme grant 086867/Z/08/Z (R.J.F. and M.P.) and Project grant 085903/Z/08 (R.J.F.) and Arthritis Research Campaign UK fellowships 18445 and 18103 (to L.V.N.
AR Rodriguez, BE Chatterjee, C Weber, Charles N. Serhan, CN Serhan, CN Serhan, CN Serhan, D Cooper, D Rittirsch, D Rittirsch, DG Souza, Dianne Cooper, DM Mosser, DW Gilroy, JA Buras, Lisa Summers, LR Farolan, Lucy V. Norling, M Bucci, MA Flierl, Matthew Spite, Mauro Perretti, MF Osuchowski, MJ Paul-Clark, Nicos A. Petasis, P Kubes, P Singer, R Haworth, Roderick J. Flower, Rong Yang, RS Hotchkiss, S Hong, S Moncada, SM Prescott, T Shimizu, T Shimizu, T Takano, TT Pluess, V Litvak, VY Dombrovskiy, X Huang   +40 more
core   +1 more source

Specialized Pro-resolving Lipid Mediators: Modulation of Diabetes-Associated Cardio-, Reno-, and Retino-Vascular Complications

Frontiers in Pharmacology, 2018
Diabetes and its associated chronic complications present a healthcare challenge on a global scale. Despite improvements in the management of chronic complications of the micro-/macro-vasculature, their growing prevalence and incidence highlights the ...
Monica de Gaetano, Caitriona McEvoy, Caitriona McEvoy, Darrell Andrews, Antonino Cacace, Jonathan Hunter, Eoin Brennan, Catherine Godson   +7 more
doaj   +1 more source

Current experimental methods to investigate the impact of specialized pro-resolving lipid mediators on Sjögren’s syndrome

Frontiers in Immunology, 2023
Sjögren’s syndrome is a chronic inflammatory autoimmune disease characterized by diminished secretory function of the exocrine glands. Although extensive investigation has been done to understand Sjögren’s syndrome, the causes of the disease are as yet ...
Harim T. dos Santos, Harim T. dos Santos, Kihoon Nam, Kihoon Nam, Diana Gil, Diana Gil, Diana Gil, Venkata Yellepeddi, Venkata Yellepeddi, Olga J. Baker, Olga J. Baker, Olga J. Baker   +11 more
doaj   +1 more source

The impact of fish oil fatty-acids on post-prandial vascular reactivity. [PDF]

, 2014
Progressive loss of vascular reactivity and increased vascular tone with age are being increasingly recognised as significant cardiovascular disease (CVD) risk factors.
Mcmanus, Sean
core  

Stress during slaughter increases lipid metabolites and decreases oxidative stability of farmed rainbow trout (Oncorhynchus mykiss) during frozen storage [PDF]

, 2016
6 páginas, 1 figura, 3 tablasThe consequences of slaughter on the formation of lipid metabolites and oxidative stability of fish muscle during long term frozen storage (−10 °C) were evaluated using farmed rainbow trout killed by asphyxia in air or ...
Dasilva, Gabriel, Medina, Isabel, Parisi, Giuliana, Secci, G.   +3 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source