Results 21 to 30 of about 17,501 (228)

Pan-Cancer Analyses Confirmed the Ferroptosis-Related Gene SLC7A11 as a Prognostic Biomarker for Cancer

International Journal of General Medicine, 2022
Yi Lin,1 Yubing Dong,2 Wanyu Liu,2 Xingyun Fan,2 Ying Sun3 1Department of Anesthesiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, 116011, People’s Republic of China; 2Department of Internal Medicine, First ...
Lin Y, Dong Y, Liu W, Fan X, Sun Y
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Hsa_circ_0070440 promotes lung adenocarcinoma progression by SLC7A11-mediated-ferroptosis.

Histology and histopathology, 2023
Circular RNA (circRNA) has recently emerged as having a key role in cancer initiation and progression. A prior study exhibited that hsa_circ_0070440 (circ_0070440) was significantly up-regulated in lung cancer cells, but the role and molecular mechanism of circ_0070440 during lung adenocarcinoma (LUAD) development remain unclear.Quantitative real-time ...
Zhao, Yong, Cui, Qichen, Shen, Jian, Shen, Weihong, Weng, Yuan   +4 more
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BAP1 suppresses tumor development by inducing ferroptosis upon SLC7A11 repression

Molecular & Cellular Oncology, 2019
The tumor suppressor BRCA1-associated protein 1 (BAP1) is a deubiquitinase that removes histone 2A ubiquitination. How BAP1 suppresses tumor development remains elusive.
Yilei Zhang, Li Zhuang, Boyi Gan
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The N6‐methyladenosine modification enhances ferroptosis resistance through inhibiting SLC7A11 mRNA deadenylation in hepatoblastoma

Clinical and Translational Medicine, 2022
Background Solute carrier family 7 member 11 (SLC7A11) is overexpressed in multiple human tumours and functions as a transporter importing cystine for glutathione biosynthesis.
Li Liu, Jiangtu He, Guifeng Sun, Nan Huang, Zhixuan Bian, Chang Xu, Yue Zhang, Zhongqi Cui, Wenqiang Xu, Fenyong Sun, Chengle Zhuang, Qiuhong Man, Song Gu   +12 more
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SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production

Frontiers in Cell and Developmental Biology, 2021
In age-related macular degeneration (AMD), one of the principal sources of vascular endothelial growth factor (VEGF) is retinal pigment epithelium (RPE) cells under hypoxia or oxidative stress. Solute carrier family 7 member 11 (SLC7A11), a key component
Xiaohuan Zhao, Xiaohuan Zhao, Xiaohuan Zhao, Xiaohuan Zhao, Min Gao, Min Gao, Min Gao, Min Gao, Jian Liang, Jian Liang, Jian Liang, Jian Liang, Yuhong Chen, Yuhong Chen, Yuhong Chen, Yuhong Chen, Yimin Wang, Yimin Wang, Yimin Wang, Yimin Wang, Yuwei Wang, Yuwei Wang, Yuwei Wang, Yuwei Wang, Yushu Xiao, Yushu Xiao, Yushu Xiao, Yushu Xiao, Zhenzhen Zhao, Zhenzhen Zhao, Zhenzhen Zhao, Zhenzhen Zhao, Xiaoling Wan, Xiaoling Wan, Xiaoling Wan, Xiaoling Wan, Mei Jiang, Mei Jiang, Mei Jiang, Mei Jiang, Xueting Luo, Xueting Luo, Xueting Luo, Xueting Luo, Feng Wang, Xiaodong Sun, Xiaodong Sun, Xiaodong Sun, Xiaodong Sun   +48 more
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SLC7A11 as a Gateway of Metabolic Perturbation and Ferroptosis Vulnerability in Cancer

Antioxidants, 2022
SLC7A11 is a cell transmembrane protein composing the light chain of system xc−, transporting extracellular cystine into cells for cysteine production and GSH biosynthesis.
Jaewang Lee, Jong-Lyel Roh
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Slc7a11 modulated by POU2F1 is involved in pigmentation in rabbit [PDF]

International Journal of Molecular Sciences, 2019
AbstractSolute carrier family 7 member 11 (Slc7a11) codes for a cystine/glutamate xCT transporter and can control production of pheomelanin pigment to change fur and skin colors of animals. Previous studies found that the skin expression levels of Slc7a11 varied significantly with the fur colors of the Rex Rabbit.
Chen, Yang, Hu, Shuaishuai, Mu, Lin, Zhao, Bohao, Wang, Manman, Yang, Naisu, Bao, Guolian, Zhu, Cigen, Wu, Xinsheng   +8 more
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RBMS1 regulates lung cancer ferroptosis through translational control of SLC7A11 [PDF]

Journal of Clinical Investigation, 2021
Ferroptosis, an iron-dependent nonapoptotic cell death, is a highly regulated tumor suppressing process. However, functions and mechanisms of RNA-binding proteins in regulation of evasion of ferroptosis during lung cancer progression are still largely unknown.
Wenjing Zhang, Yu Sun, Lu Bai, Lili Zhi, Yun Yang, Qingzhi Zhao, Chaoqun Chen, Yangfan Qi, Wenting Gao, Wenxia He, Luning Wang, Dan Chen, Shujun Fan, Huan Chen, Hai-Long Piao, Qinglong Qiao, Zhaochao Xu, Jinrui Zhang, Jinyao Zhao, Sirui Zhang, Yue Yin, Chao Peng, Xiaoling Li, Quentin Liu, Han Liu, Yang Wang   +25 more
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The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi‐omics study

Cancer Medicine, 2021
Background The ferroptosis inhibitory gene Solute carrier family 7 member 11 (SLC7A11) provides a new strategy for anticancer treatment. However, its function in renal cell carcinoma (RCC) remains elusive.
Fangshi Xu, Yibing Guan, Li Xue, Peng Zhang, Mingrui Li, Mei Gao, Tie Chong   +6 more
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Circ_0000140 Alters miR-527/SLC7A11-Mediated Ferroptosis to Influence Oral Squamous Cell Carcinoma Cell Resistance to DDP

Pharmacogenomics and Personalized Medicine, 2023
Yu Ma, Jinbo Gao, Hongning Guo Department of Stomatology, Tianjin Third Central Hospital, Tianjin, People’s Republic of ChinaCorrespondence: Yu Ma, Department of Stomatology, Tianjin Third Central Hospital, No.
Ma Y, Gao J, Guo H
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