Results 41 to 50 of about 20,364 (275)

Pan-Cancer Analyses Confirmed the Ferroptosis-Related Gene SLC7A11 as a Prognostic Biomarker for Cancer

open access: yesInternational Journal of General Medicine, 2022
Yi Lin,1 Yubing Dong,2 Wanyu Liu,2 Xingyun Fan,2 Ying Sun3 1Department of Anesthesiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, 116011, People’s Republic of China; 2Department of Internal Medicine, First ...
Lin Y, Dong Y, Liu W, Fan X, Sun Y
doaj  

Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to SLC7A11 inhibition

open access: yes, 2021
Cancer-associated fibroblasts (CAF) are major contributors to pancreatic ductal adenocarcinoma (PDAC) progression through protumor signaling and the generation of fibrosis, the latter of which creates a physical barrier to drugs.
Youkhana, Janet   +40 more
core   +1 more source

Circ_0000140 Alters miR-527/SLC7A11-Mediated Ferroptosis to Influence Oral Squamous Cell Carcinoma Cell Resistance to DDP

open access: yesPharmacogenomics and Personalized Medicine, 2023
Yu Ma, Jinbo Gao, Hongning Guo Department of Stomatology, Tianjin Third Central Hospital, Tianjin, People’s Republic of ChinaCorrespondence: Yu Ma, Department of Stomatology, Tianjin Third Central Hospital, No.
Ma Y, Gao J, Guo H
doaj  

Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes

open access: yes, 2022
Chronic non-healing wounds are a major complication of diabetes, which affects 1 in 10 people worldwide. Dying cells in the wound perpetuate the inflammation and contribute to dysregulated tissue repair1-3.
Keçeli, Burcu Nur   +12 more
core   +1 more source

Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed

open access: yesJournal of Comparative Neurology, 2015
ABSTRACTThe cystine/glutamate antiporter or system exchanges cystine for glutamate, thereby supporting intracellular glutathione synthesis and nonvesicular glutamate release. The role of system in neurological disorders can be dual and remains a matter of debate. One important reason for the contradictory findings that have been reported to date is
Van Liefferinge, Joeri   +12 more
openaire   +3 more sources

Up-Regulation of circEIF6 Contributes to Pancreatic Cancer Development Through Targeting miR-557/SLC7A11/PI3K/AKT Signaling

open access: yesCancer Management and Research, 2021
Tiequan Zhang, Mi Li, Haofeng Lu, Tao Peng Department of Hepatobiliary Surgery, The First People’s Hospital of Jingzhou, Jingzhou 434000, People’s Republic of ChinaCorrespondence: Tiequan ZhangDepartment of Hepatobiliary Surgery, The First ...
Zhang T, Li M, Lu H, Peng T
doaj  

SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production

open access: yesFrontiers in Cell and Developmental Biology, 2021
In age-related macular degeneration (AMD), one of the principal sources of vascular endothelial growth factor (VEGF) is retinal pigment epithelium (RPE) cells under hypoxia or oxidative stress. Solute carrier family 7 member 11 (SLC7A11), a key component
Xiaohuan Zhao   +48 more
doaj   +1 more source

High SLC7A11 expression in normal skin of melanoma patients [PDF]

open access: yesCancer Epidemiology, 2019
Melanoma is one of the highest metastatic cancers and its incidence is rapidly increasing. A great effort has been devoted to determine gene mutations and expression profiles in melanoma cells, but less attention has been given to the possible influence of melanin synthesis in melanocytes on melanomagenesis.
Galván, Ismael   +5 more
openaire   +5 more sources

Table_1_MiR-27a-3p Promotes Non-Small Cell Lung Cancer Through SLC7A11-Mediated-Ferroptosis.docx

open access: yes, 2021
BackgroundFerroptosis is a newly generated regulatory cell death promoted by the accumulated lipid-based reactive oxygen species (ROS). Solute carrier family 7 member 11 (SLC7A11), the cystine/glutamate antiporter, is known as a ferroptosis executor that
Xinxin Ling (11556379)   +5 more
core   +1 more source

The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi‐omics study

open access: yesCancer Medicine, 2021
Background The ferroptosis inhibitory gene Solute carrier family 7 member 11 (SLC7A11) provides a new strategy for anticancer treatment. However, its function in renal cell carcinoma (RCC) remains elusive.
Fangshi Xu   +6 more
doaj   +1 more source

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