Results 21 to 30 of about 9,094 (168)

2-Aminoetoksidifenil Borat’ ın Akut Serebral İskemi-Reperfüzyon Hasarı Üzerindeki Etkisi; Deneysel Bir Çalışma

open access: yesSakarya Tıp Dergisi, 2020
Amaç: Serebral İ/R hasarında hücre ölümüne neden olan faktörlerin başında hücre içi kalsiyum konsantrasyonundaki artış gelmektedir. Depo kontrollü Ca2+  girişi (Store operated Ca2+ entry, SOCE), hücre içine Ca2+ girişinden sorumludur ve Orai1, STIM1 ve ...
Tuba Demirci   +3 more
doaj   +1 more source

Stromal interaction molecule 2 regulates C2C12 myoblast differentiation

open access: yesIntegrative Medicine Research, 2015
Background: Enhanced intracellular Ca2+ signaling by stromal interaction molecule 1 (STIM1)-mediated store-operated Ca2+ entry (SOCE) is required for skeletal muscle differentiation. However, the contribution of STIM2, STIM1's analogue protein, on muscle
Tam Thi Thanh Phuong, Tong Mook Kang
doaj   +1 more source

CaMKII Potentiates Store-Operated Ca2+ Entry Through Enhancing STIM1 Aggregation and Interaction with Orai1

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Upon Ca2+ store depletion, stromal interaction molecule 1 (STIM1) oligomerizes, redistributes near plasmalemma to interact with Ca2+ selective channel-forming subunit (Orai1) and initiates store-operated Ca2+ entry (SOCE).
Shu Li   +9 more
doaj   +1 more source

N,N-Dimethyl-D-erythro-Sphingosine Inhibits Store-Operated Ca2+ Entry in U937 Monocytes

open access: yesJournal of Pharmacological Sciences, 2008
Calcium is a ubiquitous second messenger that controls a broad range of cellular functions, and store-operated calcium entry (SOCE) is the primary mechanism of regulated Ca2+ entry in non-excitable immunocytes. In this study, we found that N,N-dimethyl-D-
Ji-Yeong Jo   +6 more
doaj   +1 more source

Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells [PDF]

open access: yes, 2020
Calcium ions regulate a wide array of physiological functions including cell differentiation, proliferation, muscle contraction, neurotransmission, and fertilization.
Kandasamy, Palanivel   +19 more
core   +2 more sources

SOCE in the cardiomyocyte: the secret is in the chambers.

open access: yes, 2021
Store-operated Ca2+ entry (SOCE) is an ancient and ubiquitous Ca2+ signaling pathway that is present in virtually every cell type. Over the last two decades, many studies have implicated this non-voltage dependent Ca2+ entry pathway in cardiac physiology.
Wang, Chaojian   +3 more
core   +1 more source

Regulation of store-operated Ca2+ entry by Septins

open access: yesFrontiers in Cell and Developmental Biology, 2016
The mechanism of store-operated Ca2+entry (SOCE) brings extracellular Ca2+ into cells after depletion of intracellular Ca2+ stores. Regulation of Ca2+ homeostasis by SOCE helps control various intracellular signaling functions in both non-excitable and ...
Bipan Kumar Deb, Gaiti Hasan
doaj   +1 more source

A role of canonical transient receptor potential 5 channel in neuronal differentiation from A2B5 neural progenitor cells. [PDF]

open access: yesPLoS ONE, 2010
Store-operated Ca(2+) entry (SOCE) channels are the main pathway of Ca(2+) entry in non-excitable cells such as neural progenitor cells (NPCs). However, the role of SOCE channels has not been defined in the neuronal differentiation from NPCs.
Hye Young Shin   +9 more
doaj   +1 more source

Specific Upregulation of TRPC1 and TRPC5 Channels by Mineralocorticoid Pathway in Adult Rat Ventricular Cardiomyocytes

open access: yesCells, 2019
Whereas cardiac TRPC (transient receptor potential canonical) channels and the associated store-operated Ca2+ entry (SOCE) are abnormally elevated during cardiac hypertrophy and heart failure, the mechanism of this upregulation is not fully elucidated ...
Fiona Bartoli   +6 more
doaj   +1 more source

Store-operated calcium entry and the localisation of STIM1 and Orai1 proteins in isolated mouse sinoatrial node cells

open access: yesFrontiers in Physiology, 2015
In many nonexcitable and excitable cells, store-operated calcium entry (SOCE) represents an additional pathway for calcium entry upon Ca2+ store depletion.
Jie eLiu   +4 more
doaj   +1 more source

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