Results 21 to 30 of about 6,543 (175)
FASEB BioAdvances, 2023 Store‐operated Ca2+ entry (SOCE) is indispensable for intracellular Ca2+ homeostasis in skeletal muscle, and constitutive activation of SOCE causes tubular aggregate myopathy (TAM). To understand the pathogenesis of TAM, we induced pluripotent stem cells
Fusako Sakai‐Takemura +8 more
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Celastrol inhibits store operated calcium entry and suppresses psoriasis
Frontiers in Pharmacology, 2023 Introduction: Psoriasis is an inflammatory autoimmune skin disease that is hard to cure and prone to relapse. Currently available global immunosuppressive agents for psoriasis may cause severe side effects, thus it is crucial to identify new therapeutic ...
Xiaoman Yuan +15 more
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Suppression of store-operated calcium entry causes dilated cardiomyopathy of the Drosophila heart
Biology Open, 2020 Store-operated Ca2+ entry (SOCE) is an essential Ca2+ signaling mechanism present in most animal cells. SOCE refers to Ca2+ influx that is activated by depletion of sarco/endoplasmic reticulum (S/ER) Ca2+ stores.
Courtney E. Petersen +2 more
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Sakarya Tıp Dergisi, 2020 Amaç: Serebral İ/R hasarında hücre ölümüne neden olan faktörlerin başında hücre içi kalsiyum konsantrasyonundaki artış gelmektedir. Depo kontrollü Ca2+ girişi (Store operated Ca2+ entry, SOCE), hücre içine Ca2+ girişinden sorumludur ve Orai1, STIM1 ve ...
Tuba Demirci +3 more
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Stromal interaction molecule 2 regulates C2C12 myoblast differentiation
Integrative Medicine Research, 2015 Background: Enhanced intracellular Ca2+ signaling by stromal interaction molecule 1 (STIM1)-mediated store-operated Ca2+ entry (SOCE) is required for skeletal muscle differentiation. However, the contribution of STIM2, STIM1's analogue protein, on muscle
Tam Thi Thanh Phuong, Tong Mook Kang
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Cellular Physiology and Biochemistry, 2018 Background/Aims: Upon Ca2+ store depletion, stromal interaction molecule 1 (STIM1) oligomerizes, redistributes near plasmalemma to interact with Ca2+ selective channel-forming subunit (Orai1) and initiates store-operated Ca2+ entry (SOCE).
Shu Li +9 more
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N,N-Dimethyl-D-erythro-Sphingosine Inhibits Store-Operated Ca2+ Entry in U937 Monocytes
Journal of Pharmacological Sciences, 2008 Calcium is a ubiquitous second messenger that controls a broad range of cellular functions, and store-operated calcium entry (SOCE) is the primary mechanism of regulated Ca2+ entry in non-excitable immunocytes. In this study, we found that N,N-dimethyl-D-
Ji-Yeong Jo +6 more
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STIM Proteins and Regulation of SOCE in ER-PM Junctions
Biomolecules, 2022 ER-PM junctions are membrane contact sites formed by the endoplasmic reticulum (ER) and plasma membrane (PM) in close apposition together. The formation and stability of these junctions are dependent on constitutive and dynamic enrichment of proteins, which either contribute to junctional stability or modulate the lipid levels of both ER and plasma ...
Moaz Ahmad +3 more
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Regulation of store-operated Ca2+ entry by Septins
Frontiers in Cell and Developmental Biology, 2016 The mechanism of store-operated Ca2+entry (SOCE) brings extracellular Ca2+ into cells after depletion of intracellular Ca2+ stores. Regulation of Ca2+ homeostasis by SOCE helps control various intracellular signaling functions in both non-excitable and ...
Bipan Kumar Deb, Gaiti Hasan
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Dental enamel cells express functional SOCE channels [PDF]
Scientific Reports, 2015 AbstractDental enamel formation requires large quantities of Ca2+ yet the mechanisms mediating Ca2+ dynamics in enamel cells are unclear. Store-operated Ca2+ entry (SOCE) channels are important Ca2+ influx mechanisms in many cells. SOCE involves release of Ca2+ from intracellular pools followed by Ca2+ entry.
Nurbaeva, MK +9 more
openaire +4 more sources