Results 31 to 40 of about 150,601 (174)
Metabolism of N-alkylated spermine analogues by polyamine and spermine oxidases [PDF]
Amino Acids, 2009 N-alkylated polyamine analogues have potential as anticancer and antiparasitic drugs. However, their metabolism in the host has remained incompletely defined thus potentially limiting their utility. Here, we have studied the degradation of three different spermine analogues N,N'-bis-(3-ethylaminopropyl)butane-1,4-diamine (DESPM), N-(3-benzyl ...
Merja R, Häkkinen +7 more
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Biomolecules, 2023 The triamine spermidine is a key metabolite of the polyamine pathway. It plays a crucial role in many infectious diseases caused by viral or parasitic infections.
Annette Kaiser
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Reactive Astrocytosis in a Mouse Model of Chronic Polyamine Catabolism Activation
Biomolecules, 2021 Background: In the brain, polyamines are mainly synthesized in neurons, but preferentially accumulated in astrocytes, and are proposed to be involved in neurodegenerative/neuroinflammatory disorders and neuron injury.
Chiara Cervetto +11 more
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Pentamines as Substrate for Human Spermine Oxidase
Biological and Pharmaceutical Bulletin, 2013 Substrate activities of various linear polyamines to human spermine oxidase (hSMO) were investigated. The activities were evaluated by monitoring the amount of H2O2 released from sample polyamines by hSMO. H2O2 was measured by a HPLC method that analyzed fluorescent dimers derived from the oxidation of homovanillic acid in the presence of horseradish ...
Takao, Koichi +5 more
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Animals, 2021 κ-Carrageenan is a plant polysaccharide derived from red seaweeds reported to possess potential medicinal and antioxidants activities. The present study aimed to identify the cryoprotective effects of κ-carrageenan on the quality of frozen-thawed canine ...
Eunji Kim +4 more
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Molecular Characteristics of Toxicity of Acrolein Produced from Spermine
Biomolecules, 2023 Acrolein (CH2=CH-CHO), an unsaturated aldehyde produced from spermine, is one of the major contributors to oxidative stress. Acrolein has been found to be more toxic than reactive oxygen species (H2O2 and •OH), and it can be easily conjugated with ...
Keiko Kashiwagi, Kazuei Igarashi
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Lack of Influence of Spermine or Diet on Calf Spermine Oxidase Formation
Journal of Dairy Science, 1965 Abstract Studies were conducted to ascertain the changes in blood plasma spermine oxidase activity in the young dairy calf as the animal developed. Results show that there is a steady increase in plasma spermine oxidase activity up until 40-60 days of age with no further increase.
E, UEYAMA, C L, DAVIS, M J, WOLIN
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Studia Universitatis Babes-Bolyai Chemia, 2020 Grass pea amine oxidase (GPAO) and oat polyamine oxidase (OPAO) were immobilized along with horseradish peroxidase (HRP) and an Os-redox polymer (Os-RP) onto the surface of a graphite electrode by cross-linking with poly(ethylenglycol) diglycidyl ether.
Laura AQUILANTE +5 more
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Heliyon, 2020 The polyamines spermidine, spermine and putrescine are essential for normal cellular functions. The contents of polyamines in tissue decreased in aged mice compared to young mice.
Takeshi Uemura +2 more
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EFFECT OF POLYAMINES PRETREATMENTS ON THE ACTIVITY OF ANTIOXIDANT ENZYMES IN SALT STRESSED WHEAT PLANTS [PDF]
Journal of Plant Production, 2010 A pot experiment was conducted to study the effect of polyamines pretreatments, putrescine (2, 4, 6, 8 &10 mM) or spermine ( 2,4, 6,8 & 10 mM),on the activity of catalas, peroxidase, and polyphenol oxidase in salt stressed wheat plants.
Abeer Mohamed, Eglal G., Fawzia Ebad
doaj +1 more source